No difference in leprosy treatment outcomes comparing 12- and 24-dose multidrug regimens: a preliminary study

Detalhes bibliográficos
Autor(a) principal: Sales, Anna Maria
Data de Publicação: 2007
Outros Autores: Sabroza, Paulo Chagastelles, Nery, José Augusto da Costa, Dupprè, Nádia Cristina, Sarno, Euzenir Nunes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Cadernos de Saúde Pública
Texto Completo: https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3178
Resumo: A comparative study was performed on the initial and final bacillary indexes of 213 multibacillary leprosy patients who received 12 doses (Group 1: 128 patients) or 24 doses (Group 2: 85 patients) of multidrug therapy (MDT/WHO) to measure the effectiveness of the two regimens. All patients were evaluated at treatment baseline, 12 months, and 24 months. The reduction in bacillary levels and mean bacillary indexes at 24 months was similar in the two groups. No statistical difference in reaction rates was observed between the two treatment regimens.
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spelling No difference in leprosy treatment outcomes comparing 12- and 24-dose multidrug regimens: a preliminary studyLeprosyDrug TherapyComparative StudyA comparative study was performed on the initial and final bacillary indexes of 213 multibacillary leprosy patients who received 12 doses (Group 1: 128 patients) or 24 doses (Group 2: 85 patients) of multidrug therapy (MDT/WHO) to measure the effectiveness of the two regimens. All patients were evaluated at treatment baseline, 12 months, and 24 months. The reduction in bacillary levels and mean bacillary indexes at 24 months was similar in the two groups. No statistical difference in reaction rates was observed between the two treatment regimens.Foi realizado um estudo comparativo de dois grupos de pacientes definidos de acordo com o esquema terapêutico, a fim de se avaliarem os índices baciloscópicos: PQT/12 doses (Grupo 1: 128 pacientes) e PQT/24 doses (Grupo 2: 85 pacientes). Todos os pacientes foram avaliados no início do tratamento, aos 12 meses, e novamente aos 24 meses. Ao final dos 24 meses, observou-se uma redução das médias dos índices baciloscópicos, semelhantes nos dois grupos. Não houve diferença estatística na avaliação da freqüência de quadros reacionais nos dois esquemas terapêuticos.Reports in Public HealthCadernos de Saúde Pública2007-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlapplication/pdfhttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3178Reports in Public Health; Vol. 23 No. 4 (2007): AprilCadernos de Saúde Pública; v. 23 n. 4 (2007): Abril1678-44640102-311Xreponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZenghttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3178/6418https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3178/6419Sales, Anna MariaSabroza, Paulo ChagastellesNery, José Augusto da CostaDupprè, Nádia CristinaSarno, Euzenir Nunesinfo:eu-repo/semantics/openAccess2024-03-06T15:27:26Zoai:ojs.teste-cadernos.ensp.fiocruz.br:article/3178Revistahttps://cadernos.ensp.fiocruz.br/ojs/index.php/csphttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/oaicadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2024-03-06T13:03:41.925647Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)true
dc.title.none.fl_str_mv No difference in leprosy treatment outcomes comparing 12- and 24-dose multidrug regimens: a preliminary study
title No difference in leprosy treatment outcomes comparing 12- and 24-dose multidrug regimens: a preliminary study
spellingShingle No difference in leprosy treatment outcomes comparing 12- and 24-dose multidrug regimens: a preliminary study
Sales, Anna Maria
Leprosy
Drug Therapy
Comparative Study
title_short No difference in leprosy treatment outcomes comparing 12- and 24-dose multidrug regimens: a preliminary study
title_full No difference in leprosy treatment outcomes comparing 12- and 24-dose multidrug regimens: a preliminary study
title_fullStr No difference in leprosy treatment outcomes comparing 12- and 24-dose multidrug regimens: a preliminary study
title_full_unstemmed No difference in leprosy treatment outcomes comparing 12- and 24-dose multidrug regimens: a preliminary study
title_sort No difference in leprosy treatment outcomes comparing 12- and 24-dose multidrug regimens: a preliminary study
author Sales, Anna Maria
author_facet Sales, Anna Maria
Sabroza, Paulo Chagastelles
Nery, José Augusto da Costa
Dupprè, Nádia Cristina
Sarno, Euzenir Nunes
author_role author
author2 Sabroza, Paulo Chagastelles
Nery, José Augusto da Costa
Dupprè, Nádia Cristina
Sarno, Euzenir Nunes
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Sales, Anna Maria
Sabroza, Paulo Chagastelles
Nery, José Augusto da Costa
Dupprè, Nádia Cristina
Sarno, Euzenir Nunes
dc.subject.por.fl_str_mv Leprosy
Drug Therapy
Comparative Study
topic Leprosy
Drug Therapy
Comparative Study
description A comparative study was performed on the initial and final bacillary indexes of 213 multibacillary leprosy patients who received 12 doses (Group 1: 128 patients) or 24 doses (Group 2: 85 patients) of multidrug therapy (MDT/WHO) to measure the effectiveness of the two regimens. All patients were evaluated at treatment baseline, 12 months, and 24 months. The reduction in bacillary levels and mean bacillary indexes at 24 months was similar in the two groups. No statistical difference in reaction rates was observed between the two treatment regimens.
publishDate 2007
dc.date.none.fl_str_mv 2007-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3178
url https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3178
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3178/6418
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3178/6419
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
application/pdf
dc.publisher.none.fl_str_mv Reports in Public Health
Cadernos de Saúde Pública
publisher.none.fl_str_mv Reports in Public Health
Cadernos de Saúde Pública
dc.source.none.fl_str_mv Reports in Public Health; Vol. 23 No. 4 (2007): April
Cadernos de Saúde Pública; v. 23 n. 4 (2007): Abril
1678-4464
0102-311X
reponame:Cadernos de Saúde Pública
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Cadernos de Saúde Pública
collection Cadernos de Saúde Pública
repository.name.fl_str_mv Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br
_version_ 1798943359511822336

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