MALT lymphoma in rectum: complete regression after R-CHOP chemotherapy

• Autor(a) principal: de Azevedo, Leandro Rangel
• Data de Publicação: 2015
• Outros Autores: Souto Filho, João Tadeu Damian, Machado, Enilton Monteiro, de Andrade, Inêz Barcellos
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Científica da Faculdade de Medicina de Campos
• Texto Completo: https://www.fmc.br/ojs/index.php/RCFMC/article/view/29
• topic: linfoma MALT; linfoma reto; quimioterapia; R-CHOP; MALT lymphoma; rectal lymphoma; chemotherapy; R-CHOP

The mucosa-associated lymphoid tissue (MALT) lymphomas are B-cell non-Hodgkin that can arise in a number of extra nodal areas, being more frequent in the stomach. The primary presentation in the rectum is particularly rare, with few case reports. Because of its rarity, there is no consensus on the best treatment. Objective: To describe a case of MALT lymphoma in the rectum, in a female patient and their response to R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone). Methods: Descriptive study as a case report and literature review. Case report: A Woman with 55 yearsold began 4 years ago with hematochezia and tenesmus, associated with abdominal distension and feeling fullness. The patient developed asthenia and pain of weak intensity in the left upper quadrant. Had breast cancer history treated surgically and with chemotherapy for 7 years. After investigation, we performed the diagnosis of MALT lymphoma of the rectum, classified with stage II by Ann Arbor classification. Patient received 8 cycles of R-CHOP chemotherapy regimen and achieved complete remission. Conclusions: Given the rarity of presentation of MALT primary lymphoma of the rectum and the lack of consensus on the optimal treatment, we found that, through the present case, the chemotherapy treatment with R-CHOP protocol allows achieving complete remission effectively and safe.