NEW TREATMENTS FOR TYPE 2 DIABETES MELLITUS

• Autor(a) principal: Moraes, Andressa
• Data de Publicação: 2021
• Outros Autores: Belido, Bianca, Azevedo, Raphael, Haddad Kury, Charbell Miguel
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Científica da Faculdade de Medicina de Campos
• Texto Completo: https://www.fmc.br/ojs/index.php/RCFMC/article/view/506
• topic: diabetes mellitus tipo 2, tratamento, agonistas dos receptores da GLP-1, inibidores da DPP-4, inibidores da SGLT-2; type 2 diabetes mellitus, treatment, GLP-1 receptor agonists, DPP-4 inhibitors, SGLT-2 inhibitors

Introduction:  Type 2 diabetes mellitus is a chronic disease that presents high blood glucose levels and can lead to complications, requiring a change in lifestyle and the use of medications. Objectives: This is a literature review study, for which a survey of studies on new treatments of type 2 diabetes mellitus was carried out in the Google Scholar, Scientific Electronic Library Online (Scielo), PubMed and important organs databases in the area like the Brazilian Society of Diabetes and the Brazilian Society of Endocrinology and Metabology. Methods: Primarily, the diabetic patient should start a non-medication treatment with a balanced diet and physical activity. After this change, if necessary, drugs are added to help control the disease, such as metformin, sulfonylureas and thiazolinediones. These drugs can be prescribed as monotherapy or associated with other hypoglycemic agents. If the disease is not controlled with these drugs, you can include insulin supplementation or opt for the new treatments available. Conclusion: When addressing treatments for type 2 diabetes mellitus, emphasizing new therapeutic options, such as GLP-1 receptor agonists, DPP-4 inhibitors and SGLT-2 inhibitors, it is the observable the importance of studying new drugs that in addition to regulating blood glucose, it can bring other benefits such as weight loss and cardiorenal protection, depending on the medication. In this review, we emphasize the importance of changing lifestyle, in addition to adherence to drug treatment so that the damages caused by decompensating the disease do not exist or are minimized.