The Efficacy of Nasal Steroids in Treatment of Otitis Media with Effusion: A Comparative Study

Detalhes bibliográficos
Autor(a) principal: El-Anwar,Mohammad Waheed
Data de Publicação: 2015
Outros Autores: Nofal,Ahmad Abdel-Fattah, Khazbak,Alaa Omar, Sayed,Ahmad Ebrahim El, Hassan,Mohammad Ramadan
Tipo de documento: Artigo
Idioma: eng
Título da fonte: International Archives of Otorhinolaryngology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-48642015000400298
Resumo: Introduction Otitis media with effusion (OME) continues to be an important pediatric clinical problem, and more studies are needed to decide the proper treatment for it. Objective To assess the efficacy of nasal steroids in the management of OME by comparing its results with that of oral steroid and that of nasal saline spray as placebo. Methods This study was carried on 60 patients with OME who were divided into three groups: in group 1, 20 patients received mometasone furoate spray, one puff in each nostril daily, for 3 months; in group 2, 20 patients received oral prednisolone, 5 mg three times per day for the first 3 weeks; in group 3, 20 patients received nasal saline spray, one puff in each nostril daily for 3 months. Results A highly significant difference between systemic or topical (nasal spray) steroid therapy and saline nasal spray was detected (p < 0.001), and the difference between systemic and topical steroid was nonsignificant (p > 0.05). Conclusion Nasal steroid spray can be used as an effective treatment for OME, giving a significant result similar to systemic steroid. Further studies are needed to investigate its use for longer duration and in recurrent cases.
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spelling The Efficacy of Nasal Steroids in Treatment of Otitis Media with Effusion: A Comparative Studyotitis media with effusionnasal steroidstympanometry Introduction Otitis media with effusion (OME) continues to be an important pediatric clinical problem, and more studies are needed to decide the proper treatment for it. Objective To assess the efficacy of nasal steroids in the management of OME by comparing its results with that of oral steroid and that of nasal saline spray as placebo. Methods This study was carried on 60 patients with OME who were divided into three groups: in group 1, 20 patients received mometasone furoate spray, one puff in each nostril daily, for 3 months; in group 2, 20 patients received oral prednisolone, 5 mg three times per day for the first 3 weeks; in group 3, 20 patients received nasal saline spray, one puff in each nostril daily for 3 months. Results A highly significant difference between systemic or topical (nasal spray) steroid therapy and saline nasal spray was detected (p < 0.001), and the difference between systemic and topical steroid was nonsignificant (p > 0.05). Conclusion Nasal steroid spray can be used as an effective treatment for OME, giving a significant result similar to systemic steroid. Further studies are needed to investigate its use for longer duration and in recurrent cases.Fundação Otorrinolaringologia2015-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-48642015000400298International Archives of Otorhinolaryngology v.19 n.4 2015reponame:International Archives of Otorhinolaryngologyinstname:Fundação Otorrinolaringologia (FORL)instacron:FORL10.1055/s-0035-1548535info:eu-repo/semantics/openAccessEl-Anwar,Mohammad WaheedNofal,Ahmad Abdel-FattahKhazbak,Alaa OmarSayed,Ahmad Ebrahim ElHassan,Mohammad Ramadaneng2015-12-11T00:00:00Zoai:scielo:S1809-48642015000400298Revistahttps://www.scielo.br/j/iao/https://old.scielo.br/oai/scielo-oai.php||iaorl@iaorl.org||archives@internationalarchivesent.org||arquivos@forl.org.br1809-48641809-4864opendoar:2015-12-11T00:00International Archives of Otorhinolaryngology - Fundação Otorrinolaringologia (FORL)false
dc.title.none.fl_str_mv The Efficacy of Nasal Steroids in Treatment of Otitis Media with Effusion: A Comparative Study
title The Efficacy of Nasal Steroids in Treatment of Otitis Media with Effusion: A Comparative Study
spellingShingle The Efficacy of Nasal Steroids in Treatment of Otitis Media with Effusion: A Comparative Study
El-Anwar,Mohammad Waheed
otitis media with effusion
nasal steroids
tympanometry
title_short The Efficacy of Nasal Steroids in Treatment of Otitis Media with Effusion: A Comparative Study
title_full The Efficacy of Nasal Steroids in Treatment of Otitis Media with Effusion: A Comparative Study
title_fullStr The Efficacy of Nasal Steroids in Treatment of Otitis Media with Effusion: A Comparative Study
title_full_unstemmed The Efficacy of Nasal Steroids in Treatment of Otitis Media with Effusion: A Comparative Study
title_sort The Efficacy of Nasal Steroids in Treatment of Otitis Media with Effusion: A Comparative Study
author El-Anwar,Mohammad Waheed
author_facet El-Anwar,Mohammad Waheed
Nofal,Ahmad Abdel-Fattah
Khazbak,Alaa Omar
Sayed,Ahmad Ebrahim El
Hassan,Mohammad Ramadan
author_role author
author2 Nofal,Ahmad Abdel-Fattah
Khazbak,Alaa Omar
Sayed,Ahmad Ebrahim El
Hassan,Mohammad Ramadan
author2_role author
author
author
author
dc.contributor.author.fl_str_mv El-Anwar,Mohammad Waheed
Nofal,Ahmad Abdel-Fattah
Khazbak,Alaa Omar
Sayed,Ahmad Ebrahim El
Hassan,Mohammad Ramadan
dc.subject.por.fl_str_mv otitis media with effusion
nasal steroids
tympanometry
topic otitis media with effusion
nasal steroids
tympanometry
description Introduction Otitis media with effusion (OME) continues to be an important pediatric clinical problem, and more studies are needed to decide the proper treatment for it. Objective To assess the efficacy of nasal steroids in the management of OME by comparing its results with that of oral steroid and that of nasal saline spray as placebo. Methods This study was carried on 60 patients with OME who were divided into three groups: in group 1, 20 patients received mometasone furoate spray, one puff in each nostril daily, for 3 months; in group 2, 20 patients received oral prednisolone, 5 mg three times per day for the first 3 weeks; in group 3, 20 patients received nasal saline spray, one puff in each nostril daily for 3 months. Results A highly significant difference between systemic or topical (nasal spray) steroid therapy and saline nasal spray was detected (p < 0.001), and the difference between systemic and topical steroid was nonsignificant (p > 0.05). Conclusion Nasal steroid spray can be used as an effective treatment for OME, giving a significant result similar to systemic steroid. Further studies are needed to investigate its use for longer duration and in recurrent cases.
publishDate 2015
dc.date.none.fl_str_mv 2015-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-48642015000400298
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-48642015000400298
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1055/s-0035-1548535
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Fundação Otorrinolaringologia
publisher.none.fl_str_mv Fundação Otorrinolaringologia
dc.source.none.fl_str_mv International Archives of Otorhinolaryngology v.19 n.4 2015
reponame:International Archives of Otorhinolaryngology
instname:Fundação Otorrinolaringologia (FORL)
instacron:FORL
instname_str Fundação Otorrinolaringologia (FORL)
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institution FORL
reponame_str International Archives of Otorhinolaryngology
collection International Archives of Otorhinolaryngology
repository.name.fl_str_mv International Archives of Otorhinolaryngology - Fundação Otorrinolaringologia (FORL)
repository.mail.fl_str_mv ||iaorl@iaorl.org||archives@internationalarchivesent.org||arquivos@forl.org.br
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