Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei

Detalhes bibliográficos
Autor(a) principal: Gauch, Lurdete Maria Rocha
Data de Publicação: 2014
Outros Autores: Pedrosa, Simone Soares, Esteves, Renata Antunes, Gomes, Fabíola Silveira, Gurgel, Ely Simone Cajueiro, Arruda, Alberto Cardoso, Silva, Silvia Helena Marques da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
Texto Completo: https://patua.iec.gov.br/handle/iec/2981
Resumo: The antifungal and anti-germ tube formation activity of Rosmarinus officinalis Linn. essential oil was tested against four Candida strains (C. albicans, C. dubliniensis, C. parapsilosis and C. krusei). Inhibition halo sizes and minimal inhibitory concentrations (MIC) were obtained using radial diffusion and micro dilution tests, respectively. The minimal fungicidal concentration (MFC) was obtained from the MIC assay. Additionally, the effect of the essential oil on germ tube formation in C. albicans and C. dubliniensis was evaluated. The MIC50 ranged from 0.5% to 2%, while the MFC ranged from 1% to 2%. We observed total inhibition of germ tube formation in C. albicans and C. dubliniensis. The R. officinalis Linn. essential oil displayed powerful inhibitory and fungicidal activity against specific Candida strains.
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spelling Gauch, Lurdete Maria RochaPedrosa, Simone SoaresEsteves, Renata AntunesGomes, Fabíola SilveiraGurgel, Ely Simone CajueiroArruda, Alberto CardosoSilva, Silvia Helena Marques da2018-02-20T16:29:56Z2018-02-20T16:29:56Z2014GAUCH, Lurdete Maria Rocha et al. Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei. Revista Pan-Amazônica de Saúde, v. 5, n. 1, p. 61-66, mar. 2014. Disponível em: < http://scielo.iec.pa.gov.br/scielo.php?script=sci_arttext&pid=S2176-62232014000100007&lng=pt&nrm=iso&tlng=en>. Acesso em: 26 fev. 2018.2176-6223https://patua.iec.gov.br/handle/iec/298110.5123/S2176-62232014000100007The antifungal and anti-germ tube formation activity of Rosmarinus officinalis Linn. essential oil was tested against four Candida strains (C. albicans, C. dubliniensis, C. parapsilosis and C. krusei). Inhibition halo sizes and minimal inhibitory concentrations (MIC) were obtained using radial diffusion and micro dilution tests, respectively. The minimal fungicidal concentration (MFC) was obtained from the MIC assay. Additionally, the effect of the essential oil on germ tube formation in C. albicans and C. dubliniensis was evaluated. The MIC50 ranged from 0.5% to 2%, while the MFC ranged from 1% to 2%. We observed total inhibition of germ tube formation in C. albicans and C. dubliniensis. The R. officinalis Linn. essential oil displayed powerful inhibitory and fungicidal activity against specific Candida strains.A atividade de formação do tubo antifúngico e antigerme do óleo essencial de Rosmarinus officinalis Linn. foi testado contra quatro cepas de Candida (C. albicans, C. dubliniensis, C. parapsilosis e C. krusei). Halos de inibição e concentração inibitória mínima (MIC) foram obtidos utilizando os testes de difusão radial e de microdiluição, respectivamente. A concentração fungicida mínima (MFC) foi obtida por meio de ensaio da MIC. Além disso, o efeito do óleo essencial na formação do tubo germinativo de C. albicans e C. dubliniensi foi avaliado. A MIC50 variou de 0,5% a 2%, enquanto a MFC variou de 1% a 2%. Observou-se a inibição total do crescimento do tubo germinativo em C. albicans e C. dubliniensis. O óleo essencial de R. officinalis Linn. demonstrou potente atividade inibitória e fungicida contra cepas específicas de Candida.Universidade Federal do Pará. Instituto de Ciências Biológicas. Programa de Pós-graduação em Biologia de Agentes Infecciosos e Parasitários. Belém, PA, Brasil / Universidade Federal do Pará. Instituto de Ciências da Saúde. Faculdade de Odontologia. Belém, PA, Brasil.Universidade Federal do Pará. Instituto de Ciências da Saúde. Faculdade de Odontologia. Belém, PA, Brasil.Universidade Federal do Pará. Instituto de Ciências da Saúde. Faculdade de Odontologia. Belém, PA, Brasil.Universidade Federal do Pará. Instituto de Ciências Biológicas. Programa de Pós-graduação em Biologia de Agentes Infecciosos e Parasitários. Belém, PA, Brasil.Museu Paraense Emílio Goeldi. Laboratório de Botânica. Belém, PA, Brasil.Universidade Federal do Pará. Instituto de Ciências Exatas e Naturais. Laboratório de Extração. Belém, PA, BrasilMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.engInstituto Evandro ChagasAntifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida kruseiAtividade antifúngica de Rosmarinus officinalis Linn. óleo essencial contra Candida albicans, Candida dubliniensis, Candida parapsilosis e Candida kruseiActividad antifúngica de Rosmarinus officinalis Linn. aceite esencial contra Candida albicans, Candida dubliniensis, Candida parapsilosis y Candida kruseiinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleCandida / imunologiaRosmarinus officinalis / uso terapêuticoÓleos Voláteis / uso terapêuticoRosmarinus officinalis / farmacologiainfo:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALAntifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei.pdfAntifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei.pdfapplication/pdf357315https://patua.iec.gov.br/bitstreams/25f9e5a9-88ab-49f9-b828-0ae8a23d052d/download350f7a5b3092ada60a52aad0f332d26eMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-871https://patua.iec.gov.br/bitstreams/60e7111a-ba52-4ddf-a873-34301d13d715/download52f1732ea66fbd1123abe39f5373b797MD52TEXTAntifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei.pdf.txtAntifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei.pdf.txtExtracted texttext/plain23315https://patua.iec.gov.br/bitstreams/b8feb9c6-9fac-466c-a3f0-164faffd25a5/download6f7c2e0121132ef35585159211b7a82fMD55THUMBNAILAntifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei.pdf.jpgAntifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei.pdf.jpgGenerated Thumbnailimage/jpeg5599https://patua.iec.gov.br/bitstreams/8c68ab5a-ef53-4c97-8ee9-933f031a4711/download2e8b029acc0fec347a35752dca73cd77MD56iec/29812022-10-20 21:15:24.595oai:patua.iec.gov.br:iec/2981https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2022-10-20T21:15:24Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC)falseVG9kb3Mgb3MgZG9jdW1lbnRvcyBkZXNzYSBjb2xlw6fDo28gc2VndWVtIGEgTGljZW7Dp2EgQ3JlYXRpdmUgY29tbW9ucy4=
dc.title.en_US.fl_str_mv Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei
dc.title.alternative.pt_BR.fl_str_mv Atividade antifúngica de Rosmarinus officinalis Linn. óleo essencial contra Candida albicans, Candida dubliniensis, Candida parapsilosis e Candida krusei
Actividad antifúngica de Rosmarinus officinalis Linn. aceite esencial contra Candida albicans, Candida dubliniensis, Candida parapsilosis y Candida krusei
title Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei
spellingShingle Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei
Gauch, Lurdete Maria Rocha
Candida / imunologia
Rosmarinus officinalis / uso terapêutico
Óleos Voláteis / uso terapêutico
Rosmarinus officinalis / farmacologia
title_short Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei
title_full Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei
title_fullStr Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei
title_full_unstemmed Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei
title_sort Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei
author Gauch, Lurdete Maria Rocha
author_facet Gauch, Lurdete Maria Rocha
Pedrosa, Simone Soares
Esteves, Renata Antunes
Gomes, Fabíola Silveira
Gurgel, Ely Simone Cajueiro
Arruda, Alberto Cardoso
Silva, Silvia Helena Marques da
author_role author
author2 Pedrosa, Simone Soares
Esteves, Renata Antunes
Gomes, Fabíola Silveira
Gurgel, Ely Simone Cajueiro
Arruda, Alberto Cardoso
Silva, Silvia Helena Marques da
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gauch, Lurdete Maria Rocha
Pedrosa, Simone Soares
Esteves, Renata Antunes
Gomes, Fabíola Silveira
Gurgel, Ely Simone Cajueiro
Arruda, Alberto Cardoso
Silva, Silvia Helena Marques da
dc.subject.decsPrimary.pt_BR.fl_str_mv Candida / imunologia
Rosmarinus officinalis / uso terapêutico
Óleos Voláteis / uso terapêutico
Rosmarinus officinalis / farmacologia
topic Candida / imunologia
Rosmarinus officinalis / uso terapêutico
Óleos Voláteis / uso terapêutico
Rosmarinus officinalis / farmacologia
description The antifungal and anti-germ tube formation activity of Rosmarinus officinalis Linn. essential oil was tested against four Candida strains (C. albicans, C. dubliniensis, C. parapsilosis and C. krusei). Inhibition halo sizes and minimal inhibitory concentrations (MIC) were obtained using radial diffusion and micro dilution tests, respectively. The minimal fungicidal concentration (MFC) was obtained from the MIC assay. Additionally, the effect of the essential oil on germ tube formation in C. albicans and C. dubliniensis was evaluated. The MIC50 ranged from 0.5% to 2%, while the MFC ranged from 1% to 2%. We observed total inhibition of germ tube formation in C. albicans and C. dubliniensis. The R. officinalis Linn. essential oil displayed powerful inhibitory and fungicidal activity against specific Candida strains.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2018-02-20T16:29:56Z
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dc.identifier.citation.fl_str_mv GAUCH, Lurdete Maria Rocha et al. Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei. Revista Pan-Amazônica de Saúde, v. 5, n. 1, p. 61-66, mar. 2014. Disponível em: < http://scielo.iec.pa.gov.br/scielo.php?script=sci_arttext&pid=S2176-62232014000100007&lng=pt&nrm=iso&tlng=en>. Acesso em: 26 fev. 2018.
dc.identifier.uri.fl_str_mv https://patua.iec.gov.br/handle/iec/2981
dc.identifier.issn.-.fl_str_mv 2176-6223
dc.identifier.doi.-.fl_str_mv 10.5123/S2176-62232014000100007
identifier_str_mv GAUCH, Lurdete Maria Rocha et al. Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei. Revista Pan-Amazônica de Saúde, v. 5, n. 1, p. 61-66, mar. 2014. Disponível em: < http://scielo.iec.pa.gov.br/scielo.php?script=sci_arttext&pid=S2176-62232014000100007&lng=pt&nrm=iso&tlng=en>. Acesso em: 26 fev. 2018.
2176-6223
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