MHC structure and function − antigen presentation. Part 2

Detalhes bibliográficos
Autor(a) principal: Goldberg,Anna Carla
Data de Publicação: 2015
Outros Autores: Rizzo,Luiz Vicente
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Einstein (São Paulo)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000100028
Resumo: The second part of this review deals with the molecules and processes involved in the processing and presentation of the antigenic fragments to the T-cell receptor. Though the nature of the antigens presented varies, the most significant class of antigens is proteins, processed within the cell to be then recognized in the form of peptides, a mechanism that confers an extraordinary degree of precision to this mode of immune response. The efficiency and accuracy of this system is also the result of the myriad of mechanisms involved in the processing of proteins and production of peptides, in addition to the capture and recycling of alternative sources aiming to generate further diversity in the presentation to T-cells.
id IIEPAE-1_3116e5f745f2eacc1231f92ecbf693a6
oai_identifier_str oai:scielo:S1679-45082015000100028
network_acronym_str IIEPAE-1
network_name_str Einstein (São Paulo)
repository_id_str
spelling MHC structure and function − antigen presentation. Part 2Major histocompatibility complexAntigen presentation; HLA genesImmune responseThe second part of this review deals with the molecules and processes involved in the processing and presentation of the antigenic fragments to the T-cell receptor. Though the nature of the antigens presented varies, the most significant class of antigens is proteins, processed within the cell to be then recognized in the form of peptides, a mechanism that confers an extraordinary degree of precision to this mode of immune response. The efficiency and accuracy of this system is also the result of the myriad of mechanisms involved in the processing of proteins and production of peptides, in addition to the capture and recycling of alternative sources aiming to generate further diversity in the presentation to T-cells.Instituto Israelita de Ensino e Pesquisa Albert Einstein2015-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000100028einstein (São Paulo) v.13 n.1 2015reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.1590/S1679-45082015RB3123info:eu-repo/semantics/openAccessGoldberg,Anna CarlaRizzo,Luiz Vicenteeng2015-08-03T00:00:00Zoai:scielo:S1679-45082015000100028Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2015-08-03T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false
dc.title.none.fl_str_mv MHC structure and function − antigen presentation. Part 2
title MHC structure and function − antigen presentation. Part 2
spellingShingle MHC structure and function − antigen presentation. Part 2
Goldberg,Anna Carla
Major histocompatibility complex
Antigen presentation; HLA genes
Immune response
title_short MHC structure and function − antigen presentation. Part 2
title_full MHC structure and function − antigen presentation. Part 2
title_fullStr MHC structure and function − antigen presentation. Part 2
title_full_unstemmed MHC structure and function − antigen presentation. Part 2
title_sort MHC structure and function − antigen presentation. Part 2
author Goldberg,Anna Carla
author_facet Goldberg,Anna Carla
Rizzo,Luiz Vicente
author_role author
author2 Rizzo,Luiz Vicente
author2_role author
dc.contributor.author.fl_str_mv Goldberg,Anna Carla
Rizzo,Luiz Vicente
dc.subject.por.fl_str_mv Major histocompatibility complex
Antigen presentation; HLA genes
Immune response
topic Major histocompatibility complex
Antigen presentation; HLA genes
Immune response
description The second part of this review deals with the molecules and processes involved in the processing and presentation of the antigenic fragments to the T-cell receptor. Though the nature of the antigens presented varies, the most significant class of antigens is proteins, processed within the cell to be then recognized in the form of peptides, a mechanism that confers an extraordinary degree of precision to this mode of immune response. The efficiency and accuracy of this system is also the result of the myriad of mechanisms involved in the processing of proteins and production of peptides, in addition to the capture and recycling of alternative sources aiming to generate further diversity in the presentation to T-cells.
publishDate 2015
dc.date.none.fl_str_mv 2015-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000100028
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000100028
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1679-45082015RB3123
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
dc.source.none.fl_str_mv einstein (São Paulo) v.13 n.1 2015
reponame:Einstein (São Paulo)
instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron:IIEPAE
instname_str Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron_str IIEPAE
institution IIEPAE
reponame_str Einstein (São Paulo)
collection Einstein (São Paulo)
repository.name.fl_str_mv Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
repository.mail.fl_str_mv ||revista@einstein.br
_version_ 1752129908303200256

Registros relacionados