Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT)

Detalhes bibliográficos
Autor(a) principal: Lastória, Joel Carlos
Data de Publicação: 2006
Outros Autores: Putinatti, Maria Stella Mello Ayres, Diório, Suzana Madeira, Trino, Lazara Moreira, Padovan, Carlos Roberto
Tipo de documento: Artigo
Idioma: por
Título da fonte: Hansenologia Internationalis (Online)
Texto Completo: https://periodicos.saude.sp.gov.br/hansenologia/article/view/35211
Resumo: Leprosy is a chronic infectious disease caused by Mycobacterium leprae, highly prevalent in Brazil. The recommended treatment for the multibacillary forms is the 12 months of the multidrugtherapy, afterwards patients are discharged without any need of bacteriological evaluation. The authors evaluated 73 multibacillary leprosy patients and evaluated the  orphologic index before and after treatment. All borderline forms were negative and 20.54% of the bacilloscopic indexes were positive in the lepromatous form. These patients continued to receive the medication up to 24 months, and still 6.97% were positive. The authors suggest that the bacilloscopic and morphologic indexes should be done at the end of the treatment and in the positive morphologic index cases. Such patients should continue receiving the medication for 24 months, avoiding thus possible relapses and transmission. The same is recommended for immunosupressed patients.
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spelling Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT)Índices baciloscópicos e morfológico na hanseníase após doze doses do esquema poliquimioterápico (PQT/OMS)hanseníasetratamentoíndice morfológicoleprosytreatmentmorphologic indexLeprosy is a chronic infectious disease caused by Mycobacterium leprae, highly prevalent in Brazil. The recommended treatment for the multibacillary forms is the 12 months of the multidrugtherapy, afterwards patients are discharged without any need of bacteriological evaluation. The authors evaluated 73 multibacillary leprosy patients and evaluated the  orphologic index before and after treatment. All borderline forms were negative and 20.54% of the bacilloscopic indexes were positive in the lepromatous form. These patients continued to receive the medication up to 24 months, and still 6.97% were positive. The authors suggest that the bacilloscopic and morphologic indexes should be done at the end of the treatment and in the positive morphologic index cases. Such patients should continue receiving the medication for 24 months, avoiding thus possible relapses and transmission. The same is recommended for immunosupressed patients.A hanseníase é uma doença infecciosa crônica causada pelo Mycobacterium leprae e que ainda apresenta altas taxas de prevalência nas regiões norte, nordeste e centro-oeste do Brasil. Atualmente, o esquema poliquimioterápico (PQT) preconizado para os pacientes multibacilares tem duração de 12 meses; após o término da última dose esses pacientes recebem alta, sem a necessidade de qualquer avaliação bacteriológica. No presente estudo avaliou-se os índices baciloscópico (IB) e morfológico (IM) de 73 pacientes multibacilares, no momento do diagnóstico e ao final de 12 doses da PQT. Após o término das 12 doses, o IM foi positivo em 20,54% deles, sendo todos virchovianos; esses pacientes continuaram a receber a medicação até 24 meses, persistindo a positividade em 4,11% deles; estes continuaram com a medicação até a negativação do IM. Neste sentido, os autores sugerem que os IB e IM deveriam ser realizados ao final do tratamento e, nos casos de positividade do IM, os pacientes poderiam continuar recebendo a medicação por 24 meses ou mais, evitando, assim, possíveis recidivas e transmissão. A mesma recomendação é feita para pacientes portadores de alguma imunodeficiência.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo2006-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3521110.47878/hi.2006.v31.35211Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 31 No. 1 (2006); 15-21Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 31 n. 1 (2006); 15-211982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLporhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/35211/33673Lastória, Joel CarlosPutinatti, Maria Stella Mello AyresDiório, Suzana MadeiraTrino, Lazara MoreiraPadovan, Carlos Robertoinfo:eu-repo/semantics/openAccess2021-05-19T21:25:38Zoai:ojs.periodicos.saude.sp.gov.br:article/35211Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2021-05-19T21:25:38Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false
dc.title.none.fl_str_mv Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT)
Índices baciloscópicos e morfológico na hanseníase após doze doses do esquema poliquimioterápico (PQT/OMS)
title Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT)
spellingShingle Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT)
Lastória, Joel Carlos
hanseníase
tratamento
índice morfológico
leprosy
treatment
morphologic index
title_short Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT)
title_full Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT)
title_fullStr Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT)
title_full_unstemmed Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT)
title_sort Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT)
author Lastória, Joel Carlos
author_facet Lastória, Joel Carlos
Putinatti, Maria Stella Mello Ayres
Diório, Suzana Madeira
Trino, Lazara Moreira
Padovan, Carlos Roberto
author_role author
author2 Putinatti, Maria Stella Mello Ayres
Diório, Suzana Madeira
Trino, Lazara Moreira
Padovan, Carlos Roberto
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Lastória, Joel Carlos
Putinatti, Maria Stella Mello Ayres
Diório, Suzana Madeira
Trino, Lazara Moreira
Padovan, Carlos Roberto
dc.subject.por.fl_str_mv hanseníase
tratamento
índice morfológico
leprosy
treatment
morphologic index
topic hanseníase
tratamento
índice morfológico
leprosy
treatment
morphologic index
description Leprosy is a chronic infectious disease caused by Mycobacterium leprae, highly prevalent in Brazil. The recommended treatment for the multibacillary forms is the 12 months of the multidrugtherapy, afterwards patients are discharged without any need of bacteriological evaluation. The authors evaluated 73 multibacillary leprosy patients and evaluated the  orphologic index before and after treatment. All borderline forms were negative and 20.54% of the bacilloscopic indexes were positive in the lepromatous form. These patients continued to receive the medication up to 24 months, and still 6.97% were positive. The authors suggest that the bacilloscopic and morphologic indexes should be done at the end of the treatment and in the positive morphologic index cases. Such patients should continue receiving the medication for 24 months, avoiding thus possible relapses and transmission. The same is recommended for immunosupressed patients.
publishDate 2006
dc.date.none.fl_str_mv 2006-06-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/35211
10.47878/hi.2006.v31.35211
url https://periodicos.saude.sp.gov.br/hansenologia/article/view/35211
identifier_str_mv 10.47878/hi.2006.v31.35211
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/35211/33673
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
dc.source.none.fl_str_mv Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 31 No. 1 (2006); 15-21
Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 31 n. 1 (2006); 15-21
1982-5161
reponame:Hansenologia Internationalis (Online)
instname:Instituto Lauro de Souza Lima (ILSL)
instacron:ILSL
instname_str Instituto Lauro de Souza Lima (ILSL)
instacron_str ILSL
institution ILSL
reponame_str Hansenologia Internationalis (Online)
collection Hansenologia Internationalis (Online)
repository.name.fl_str_mv Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)
repository.mail.fl_str_mv hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br
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