Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT)
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Hansenologia Internationalis (Online) |
Texto Completo: | https://periodicos.saude.sp.gov.br/hansenologia/article/view/35211 |
Resumo: | Leprosy is a chronic infectious disease caused by Mycobacterium leprae, highly prevalent in Brazil. The recommended treatment for the multibacillary forms is the 12 months of the multidrugtherapy, afterwards patients are discharged without any need of bacteriological evaluation. The authors evaluated 73 multibacillary leprosy patients and evaluated the orphologic index before and after treatment. All borderline forms were negative and 20.54% of the bacilloscopic indexes were positive in the lepromatous form. These patients continued to receive the medication up to 24 months, and still 6.97% were positive. The authors suggest that the bacilloscopic and morphologic indexes should be done at the end of the treatment and in the positive morphologic index cases. Such patients should continue receiving the medication for 24 months, avoiding thus possible relapses and transmission. The same is recommended for immunosupressed patients. |
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Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT)Índices baciloscópicos e morfológico na hanseníase após doze doses do esquema poliquimioterápico (PQT/OMS)hanseníasetratamentoíndice morfológicoleprosytreatmentmorphologic indexLeprosy is a chronic infectious disease caused by Mycobacterium leprae, highly prevalent in Brazil. The recommended treatment for the multibacillary forms is the 12 months of the multidrugtherapy, afterwards patients are discharged without any need of bacteriological evaluation. The authors evaluated 73 multibacillary leprosy patients and evaluated the orphologic index before and after treatment. All borderline forms were negative and 20.54% of the bacilloscopic indexes were positive in the lepromatous form. These patients continued to receive the medication up to 24 months, and still 6.97% were positive. The authors suggest that the bacilloscopic and morphologic indexes should be done at the end of the treatment and in the positive morphologic index cases. Such patients should continue receiving the medication for 24 months, avoiding thus possible relapses and transmission. The same is recommended for immunosupressed patients.A hanseníase é uma doença infecciosa crônica causada pelo Mycobacterium leprae e que ainda apresenta altas taxas de prevalência nas regiões norte, nordeste e centro-oeste do Brasil. Atualmente, o esquema poliquimioterápico (PQT) preconizado para os pacientes multibacilares tem duração de 12 meses; após o término da última dose esses pacientes recebem alta, sem a necessidade de qualquer avaliação bacteriológica. No presente estudo avaliou-se os índices baciloscópico (IB) e morfológico (IM) de 73 pacientes multibacilares, no momento do diagnóstico e ao final de 12 doses da PQT. Após o término das 12 doses, o IM foi positivo em 20,54% deles, sendo todos virchovianos; esses pacientes continuaram a receber a medicação até 24 meses, persistindo a positividade em 4,11% deles; estes continuaram com a medicação até a negativação do IM. Neste sentido, os autores sugerem que os IB e IM deveriam ser realizados ao final do tratamento e, nos casos de positividade do IM, os pacientes poderiam continuar recebendo a medicação por 24 meses ou mais, evitando, assim, possíveis recidivas e transmissão. A mesma recomendação é feita para pacientes portadores de alguma imunodeficiência.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo2006-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3521110.47878/hi.2006.v31.35211Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 31 No. 1 (2006); 15-21Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 31 n. 1 (2006); 15-211982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLporhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/35211/33673Lastória, Joel CarlosPutinatti, Maria Stella Mello AyresDiório, Suzana MadeiraTrino, Lazara MoreiraPadovan, Carlos Robertoinfo:eu-repo/semantics/openAccess2021-05-19T21:25:38Zoai:ojs.periodicos.saude.sp.gov.br:article/35211Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2021-05-19T21:25:38Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false |
dc.title.none.fl_str_mv |
Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT) Índices baciloscópicos e morfológico na hanseníase após doze doses do esquema poliquimioterápico (PQT/OMS) |
title |
Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT) |
spellingShingle |
Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT) Lastória, Joel Carlos hanseníase tratamento índice morfológico leprosy treatment morphologic index |
title_short |
Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT) |
title_full |
Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT) |
title_fullStr |
Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT) |
title_full_unstemmed |
Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT) |
title_sort |
Bacilloscopic and morphologic indexes in leprosy after twelve doses of multidrug therapy (WHO/MDT) |
author |
Lastória, Joel Carlos |
author_facet |
Lastória, Joel Carlos Putinatti, Maria Stella Mello Ayres Diório, Suzana Madeira Trino, Lazara Moreira Padovan, Carlos Roberto |
author_role |
author |
author2 |
Putinatti, Maria Stella Mello Ayres Diório, Suzana Madeira Trino, Lazara Moreira Padovan, Carlos Roberto |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Lastória, Joel Carlos Putinatti, Maria Stella Mello Ayres Diório, Suzana Madeira Trino, Lazara Moreira Padovan, Carlos Roberto |
dc.subject.por.fl_str_mv |
hanseníase tratamento índice morfológico leprosy treatment morphologic index |
topic |
hanseníase tratamento índice morfológico leprosy treatment morphologic index |
description |
Leprosy is a chronic infectious disease caused by Mycobacterium leprae, highly prevalent in Brazil. The recommended treatment for the multibacillary forms is the 12 months of the multidrugtherapy, afterwards patients are discharged without any need of bacteriological evaluation. The authors evaluated 73 multibacillary leprosy patients and evaluated the orphologic index before and after treatment. All borderline forms were negative and 20.54% of the bacilloscopic indexes were positive in the lepromatous form. These patients continued to receive the medication up to 24 months, and still 6.97% were positive. The authors suggest that the bacilloscopic and morphologic indexes should be done at the end of the treatment and in the positive morphologic index cases. Such patients should continue receiving the medication for 24 months, avoiding thus possible relapses and transmission. The same is recommended for immunosupressed patients. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-06-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35211 10.47878/hi.2006.v31.35211 |
url |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35211 |
identifier_str_mv |
10.47878/hi.2006.v31.35211 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35211/33673 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
dc.source.none.fl_str_mv |
Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 31 No. 1 (2006); 15-21 Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 31 n. 1 (2006); 15-21 1982-5161 reponame:Hansenologia Internationalis (Online) instname:Instituto Lauro de Souza Lima (ILSL) instacron:ILSL |
instname_str |
Instituto Lauro de Souza Lima (ILSL) |
instacron_str |
ILSL |
institution |
ILSL |
reponame_str |
Hansenologia Internationalis (Online) |
collection |
Hansenologia Internationalis (Online) |
repository.name.fl_str_mv |
Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL) |
repository.mail.fl_str_mv |
hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br |
_version_ |
1796797578893852672 |