Conversion of the C3 component of complement in sera of hanseniasis patients

Detalhes bibliográficos
Autor(a) principal: Kliemann, Teresa A. E.
Data de Publicação: 1983
Outros Autores: Martinez, Ednir L. W., Irulegu, Ione, Souza, Zóia W. Telles de, Cavalcanti, Zélia Maria de O.I
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Hansenologia Internationalis (Online)
Texto Completo: https://periodicos.saude.sp.gov.br/hansenologia/article/view/35578
Resumo: The levels of total C3 (native C3 plus its degradation products) and the degree of conversion of native C3 into its breakdown products were studied in sera of Virchowian (V), tuberculoid (T), indeterminate (I), and Virchowian with erythema nodosum Hansenicum (ENH) patients. Sera from normal individuals (N) were also analysed. While the levels of total C3 were not significantly different among the groups, the percentage of conversion of C3 into its degradation products was significantly higher in V and ENH sera. The activation of the complement system and the involvement of immune complexes (IC) are discussed.
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spelling Conversion of the C3 component of complement in sera of hanseniasis patientsHanseníaseComplemento 3HanseniasiComplement 3The levels of total C3 (native C3 plus its degradation products) and the degree of conversion of native C3 into its breakdown products were studied in sera of Virchowian (V), tuberculoid (T), indeterminate (I), and Virchowian with erythema nodosum Hansenicum (ENH) patients. Sera from normal individuals (N) were also analysed. While the levels of total C3 were not significantly different among the groups, the percentage of conversion of C3 into its degradation products was significantly higher in V and ENH sera. The activation of the complement system and the involvement of immune complexes (IC) are discussed.Os níveis de C3 total (C3 nativo mais seus produtos de degradação) e o grau de conversão do C3 nativo em seus produtos de degradação foram estudados em soros de pacientes V, T, I e de V com ENH. Soros de indivíduos normais foram também analisados, enquanto os níveis de C3 total não diferiram significativamente entre os grupos, a conversão de C3 em seus produtos de degradação foi significativamente maior nos soros de pacientes V e naqueles com ENH. A ativação do sistema complemento e o envolvimento dos IC neste processo são discutidos.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo1983-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3557810.47878/hi.1983.v8.35578Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 8 No. 1 (1983); 5-8Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 8 n. 1 (1983); 5-81982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLenghttps://periodicos.saude.sp.gov.br/hansenologia/article/view/35578/33981Kliemann, Teresa A. E.Martinez, Ednir L. W.Irulegu, IoneSouza, Zóia W. Telles deCavalcanti, Zélia Maria de O.Iinfo:eu-repo/semantics/openAccess2021-11-23T16:55:37Zoai:ojs.periodicos.saude.sp.gov.br:article/35578Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2021-11-23T16:55:37Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false
dc.title.none.fl_str_mv Conversion of the C3 component of complement in sera of hanseniasis patients
title Conversion of the C3 component of complement in sera of hanseniasis patients
spellingShingle Conversion of the C3 component of complement in sera of hanseniasis patients
Kliemann, Teresa A. E.
Hanseníase
Complemento 3
Hanseniasi
Complement 3
title_short Conversion of the C3 component of complement in sera of hanseniasis patients
title_full Conversion of the C3 component of complement in sera of hanseniasis patients
title_fullStr Conversion of the C3 component of complement in sera of hanseniasis patients
title_full_unstemmed Conversion of the C3 component of complement in sera of hanseniasis patients
title_sort Conversion of the C3 component of complement in sera of hanseniasis patients
author Kliemann, Teresa A. E.
author_facet Kliemann, Teresa A. E.
Martinez, Ednir L. W.
Irulegu, Ione
Souza, Zóia W. Telles de
Cavalcanti, Zélia Maria de O.I
author_role author
author2 Martinez, Ednir L. W.
Irulegu, Ione
Souza, Zóia W. Telles de
Cavalcanti, Zélia Maria de O.I
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Kliemann, Teresa A. E.
Martinez, Ednir L. W.
Irulegu, Ione
Souza, Zóia W. Telles de
Cavalcanti, Zélia Maria de O.I
dc.subject.por.fl_str_mv Hanseníase
Complemento 3
Hanseniasi
Complement 3
topic Hanseníase
Complemento 3
Hanseniasi
Complement 3
description The levels of total C3 (native C3 plus its degradation products) and the degree of conversion of native C3 into its breakdown products were studied in sera of Virchowian (V), tuberculoid (T), indeterminate (I), and Virchowian with erythema nodosum Hansenicum (ENH) patients. Sera from normal individuals (N) were also analysed. While the levels of total C3 were not significantly different among the groups, the percentage of conversion of C3 into its degradation products was significantly higher in V and ENH sera. The activation of the complement system and the involvement of immune complexes (IC) are discussed.
publishDate 1983
dc.date.none.fl_str_mv 1983-06-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/35578
10.47878/hi.1983.v8.35578
url https://periodicos.saude.sp.gov.br/hansenologia/article/view/35578
identifier_str_mv 10.47878/hi.1983.v8.35578
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/35578/33981
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
dc.source.none.fl_str_mv Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 8 No. 1 (1983); 5-8
Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 8 n. 1 (1983); 5-8
1982-5161
reponame:Hansenologia Internationalis (Online)
instname:Instituto Lauro de Souza Lima (ILSL)
instacron:ILSL
instname_str Instituto Lauro de Souza Lima (ILSL)
instacron_str ILSL
institution ILSL
reponame_str Hansenologia Internationalis (Online)
collection Hansenologia Internationalis (Online)
repository.name.fl_str_mv Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)
repository.mail.fl_str_mv hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br
_version_ 1796797579773607937

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