Conversion of the C3 component of complement in sera of hanseniasis patients
Autor(a) principal: | |
---|---|
Data de Publicação: | 1983 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Hansenologia Internationalis (Online) |
Texto Completo: | https://periodicos.saude.sp.gov.br/hansenologia/article/view/35578 |
Resumo: | The levels of total C3 (native C3 plus its degradation products) and the degree of conversion of native C3 into its breakdown products were studied in sera of Virchowian (V), tuberculoid (T), indeterminate (I), and Virchowian with erythema nodosum Hansenicum (ENH) patients. Sera from normal individuals (N) were also analysed. While the levels of total C3 were not significantly different among the groups, the percentage of conversion of C3 into its degradation products was significantly higher in V and ENH sera. The activation of the complement system and the involvement of immune complexes (IC) are discussed. |
id |
ILSL-1_d00aa9c6b16aa2da60dfea9a3039fb91 |
---|---|
oai_identifier_str |
oai:ojs.periodicos.saude.sp.gov.br:article/35578 |
network_acronym_str |
ILSL-1 |
network_name_str |
Hansenologia Internationalis (Online) |
repository_id_str |
|
spelling |
Conversion of the C3 component of complement in sera of hanseniasis patientsHanseníaseComplemento 3HanseniasiComplement 3The levels of total C3 (native C3 plus its degradation products) and the degree of conversion of native C3 into its breakdown products were studied in sera of Virchowian (V), tuberculoid (T), indeterminate (I), and Virchowian with erythema nodosum Hansenicum (ENH) patients. Sera from normal individuals (N) were also analysed. While the levels of total C3 were not significantly different among the groups, the percentage of conversion of C3 into its degradation products was significantly higher in V and ENH sera. The activation of the complement system and the involvement of immune complexes (IC) are discussed.Os níveis de C3 total (C3 nativo mais seus produtos de degradação) e o grau de conversão do C3 nativo em seus produtos de degradação foram estudados em soros de pacientes V, T, I e de V com ENH. Soros de indivíduos normais foram também analisados, enquanto os níveis de C3 total não diferiram significativamente entre os grupos, a conversão de C3 em seus produtos de degradação foi significativamente maior nos soros de pacientes V e naqueles com ENH. A ativação do sistema complemento e o envolvimento dos IC neste processo são discutidos.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo1983-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3557810.47878/hi.1983.v8.35578Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 8 No. 1 (1983); 5-8Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 8 n. 1 (1983); 5-81982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLenghttps://periodicos.saude.sp.gov.br/hansenologia/article/view/35578/33981Kliemann, Teresa A. E.Martinez, Ednir L. W.Irulegu, IoneSouza, Zóia W. Telles deCavalcanti, Zélia Maria de O.Iinfo:eu-repo/semantics/openAccess2021-11-23T16:55:37Zoai:ojs.periodicos.saude.sp.gov.br:article/35578Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2021-11-23T16:55:37Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false |
dc.title.none.fl_str_mv |
Conversion of the C3 component of complement in sera of hanseniasis patients |
title |
Conversion of the C3 component of complement in sera of hanseniasis patients |
spellingShingle |
Conversion of the C3 component of complement in sera of hanseniasis patients Kliemann, Teresa A. E. Hanseníase Complemento 3 Hanseniasi Complement 3 |
title_short |
Conversion of the C3 component of complement in sera of hanseniasis patients |
title_full |
Conversion of the C3 component of complement in sera of hanseniasis patients |
title_fullStr |
Conversion of the C3 component of complement in sera of hanseniasis patients |
title_full_unstemmed |
Conversion of the C3 component of complement in sera of hanseniasis patients |
title_sort |
Conversion of the C3 component of complement in sera of hanseniasis patients |
author |
Kliemann, Teresa A. E. |
author_facet |
Kliemann, Teresa A. E. Martinez, Ednir L. W. Irulegu, Ione Souza, Zóia W. Telles de Cavalcanti, Zélia Maria de O.I |
author_role |
author |
author2 |
Martinez, Ednir L. W. Irulegu, Ione Souza, Zóia W. Telles de Cavalcanti, Zélia Maria de O.I |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Kliemann, Teresa A. E. Martinez, Ednir L. W. Irulegu, Ione Souza, Zóia W. Telles de Cavalcanti, Zélia Maria de O.I |
dc.subject.por.fl_str_mv |
Hanseníase Complemento 3 Hanseniasi Complement 3 |
topic |
Hanseníase Complemento 3 Hanseniasi Complement 3 |
description |
The levels of total C3 (native C3 plus its degradation products) and the degree of conversion of native C3 into its breakdown products were studied in sera of Virchowian (V), tuberculoid (T), indeterminate (I), and Virchowian with erythema nodosum Hansenicum (ENH) patients. Sera from normal individuals (N) were also analysed. While the levels of total C3 were not significantly different among the groups, the percentage of conversion of C3 into its degradation products was significantly higher in V and ENH sera. The activation of the complement system and the involvement of immune complexes (IC) are discussed. |
publishDate |
1983 |
dc.date.none.fl_str_mv |
1983-06-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35578 10.47878/hi.1983.v8.35578 |
url |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35578 |
identifier_str_mv |
10.47878/hi.1983.v8.35578 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35578/33981 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
dc.source.none.fl_str_mv |
Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 8 No. 1 (1983); 5-8 Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 8 n. 1 (1983); 5-8 1982-5161 reponame:Hansenologia Internationalis (Online) instname:Instituto Lauro de Souza Lima (ILSL) instacron:ILSL |
instname_str |
Instituto Lauro de Souza Lima (ILSL) |
instacron_str |
ILSL |
institution |
ILSL |
reponame_str |
Hansenologia Internationalis (Online) |
collection |
Hansenologia Internationalis (Online) |
repository.name.fl_str_mv |
Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL) |
repository.mail.fl_str_mv |
hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br |
_version_ |
1796797579773607937 |