Prevalence of comorbidities in patients and mortality cases affected by SARS-CoV2: a systematic review and meta-analysis
Autor(a) principal: | |
---|---|
Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/172428 |
Resumo: | The new coronavirus, COVID-19 was declared a pandemic by the World Health Organization on March 11, 2020. Risk factors associated with this disease are age, sex, and the presence of comorbidities, the most common being hypertension, diabetes, and heart disease. The aim of this meta-analysis was to calculate the prevalence and geographical distribution of comorbidities in all patients admitted to intensive care units (ICUs), and the mortality rate of COVID-19. We selected studies based upon epidemiological and clinical descriptions of the patients and mortality from the disease to determine the pooled prevalence of comorbidities in all patients and in mortality cases due to COVID-19. The pooled prevalence was estimated using the random effects model, and odds ratios were used to measure the probability of death for a patient with a comorbidity. The total prevalence of comorbidities in patients with COVID-19 was 42% (95% CI: 25-60), 61% (95% CI: 42-80) in those admitted to the ICU, and 77% (95% CI: 68-86) among death cases; males were the most affected. Hypertension was the most prevalent comorbidity in all three groups studied, accounting for 32%, 26%, and 35%, respectively. The odds ratio of death for a patient with a comorbidity compared to one with no comorbidity was 2.4 (P < 0.0001). The higher the prevalence of comorbidities the higher the odds that the COVID-19 patient will need intensive care or will die, especially if the pre-existing disease is hypertension, heart disease, or diabetes. |
id |
IMT-1_3079e2b46ed85009d02dfb0febc8c4f5 |
---|---|
oai_identifier_str |
oai:revistas.usp.br:article/172428 |
network_acronym_str |
IMT-1 |
network_name_str |
Revista do Instituto de Medicina Tropical de São Paulo |
repository_id_str |
|
spelling |
Prevalence of comorbidities in patients and mortality cases affected by SARS-CoV2: a systematic review and meta-analysisCOVID-19SARS-CoV2PrevalenceComorbidityMortalityMeta-analysisThe new coronavirus, COVID-19 was declared a pandemic by the World Health Organization on March 11, 2020. Risk factors associated with this disease are age, sex, and the presence of comorbidities, the most common being hypertension, diabetes, and heart disease. The aim of this meta-analysis was to calculate the prevalence and geographical distribution of comorbidities in all patients admitted to intensive care units (ICUs), and the mortality rate of COVID-19. We selected studies based upon epidemiological and clinical descriptions of the patients and mortality from the disease to determine the pooled prevalence of comorbidities in all patients and in mortality cases due to COVID-19. The pooled prevalence was estimated using the random effects model, and odds ratios were used to measure the probability of death for a patient with a comorbidity. The total prevalence of comorbidities in patients with COVID-19 was 42% (95% CI: 25-60), 61% (95% CI: 42-80) in those admitted to the ICU, and 77% (95% CI: 68-86) among death cases; males were the most affected. Hypertension was the most prevalent comorbidity in all three groups studied, accounting for 32%, 26%, and 35%, respectively. The odds ratio of death for a patient with a comorbidity compared to one with no comorbidity was 2.4 (P < 0.0001). The higher the prevalence of comorbidities the higher the odds that the COVID-19 patient will need intensive care or will die, especially if the pre-existing disease is hypertension, heart disease, or diabetes.Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2020-07-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/xmlhttps://www.revistas.usp.br/rimtsp/article/view/17242810.1590/s1678-9946202062043Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e43Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e43Revista do Instituto de Medicina Tropical de São Paulo; v. 62 (2020); e431678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/172428/162022https://www.revistas.usp.br/rimtsp/article/view/172428/162023Copyright (c) 2020 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessEspinosa, Omar ArielZanetti, Andernice dos SantosAntunes, Ednardo FornanciariLonghi, Fabiana GulinMatos, Tatiane Amorim deBattaglini, Paula Franciene2020-10-26T17:39:25Zoai:revistas.usp.br:article/172428Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:52:52.999324Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
Prevalence of comorbidities in patients and mortality cases affected by SARS-CoV2: a systematic review and meta-analysis |
title |
Prevalence of comorbidities in patients and mortality cases affected by SARS-CoV2: a systematic review and meta-analysis |
spellingShingle |
Prevalence of comorbidities in patients and mortality cases affected by SARS-CoV2: a systematic review and meta-analysis Espinosa, Omar Ariel COVID-19 SARS-CoV2 Prevalence Comorbidity Mortality Meta-analysis |
title_short |
Prevalence of comorbidities in patients and mortality cases affected by SARS-CoV2: a systematic review and meta-analysis |
title_full |
Prevalence of comorbidities in patients and mortality cases affected by SARS-CoV2: a systematic review and meta-analysis |
title_fullStr |
Prevalence of comorbidities in patients and mortality cases affected by SARS-CoV2: a systematic review and meta-analysis |
title_full_unstemmed |
Prevalence of comorbidities in patients and mortality cases affected by SARS-CoV2: a systematic review and meta-analysis |
title_sort |
Prevalence of comorbidities in patients and mortality cases affected by SARS-CoV2: a systematic review and meta-analysis |
author |
Espinosa, Omar Ariel |
author_facet |
Espinosa, Omar Ariel Zanetti, Andernice dos Santos Antunes, Ednardo Fornanciari Longhi, Fabiana Gulin Matos, Tatiane Amorim de Battaglini, Paula Franciene |
author_role |
author |
author2 |
Zanetti, Andernice dos Santos Antunes, Ednardo Fornanciari Longhi, Fabiana Gulin Matos, Tatiane Amorim de Battaglini, Paula Franciene |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Espinosa, Omar Ariel Zanetti, Andernice dos Santos Antunes, Ednardo Fornanciari Longhi, Fabiana Gulin Matos, Tatiane Amorim de Battaglini, Paula Franciene |
dc.subject.por.fl_str_mv |
COVID-19 SARS-CoV2 Prevalence Comorbidity Mortality Meta-analysis |
topic |
COVID-19 SARS-CoV2 Prevalence Comorbidity Mortality Meta-analysis |
description |
The new coronavirus, COVID-19 was declared a pandemic by the World Health Organization on March 11, 2020. Risk factors associated with this disease are age, sex, and the presence of comorbidities, the most common being hypertension, diabetes, and heart disease. The aim of this meta-analysis was to calculate the prevalence and geographical distribution of comorbidities in all patients admitted to intensive care units (ICUs), and the mortality rate of COVID-19. We selected studies based upon epidemiological and clinical descriptions of the patients and mortality from the disease to determine the pooled prevalence of comorbidities in all patients and in mortality cases due to COVID-19. The pooled prevalence was estimated using the random effects model, and odds ratios were used to measure the probability of death for a patient with a comorbidity. The total prevalence of comorbidities in patients with COVID-19 was 42% (95% CI: 25-60), 61% (95% CI: 42-80) in those admitted to the ICU, and 77% (95% CI: 68-86) among death cases; males were the most affected. Hypertension was the most prevalent comorbidity in all three groups studied, accounting for 32%, 26%, and 35%, respectively. The odds ratio of death for a patient with a comorbidity compared to one with no comorbidity was 2.4 (P < 0.0001). The higher the prevalence of comorbidities the higher the odds that the COVID-19 patient will need intensive care or will die, especially if the pre-existing disease is hypertension, heart disease, or diabetes. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-07-14 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/172428 10.1590/s1678-9946202062043 |
url |
https://www.revistas.usp.br/rimtsp/article/view/172428 |
identifier_str_mv |
10.1590/s1678-9946202062043 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/172428/162022 https://www.revistas.usp.br/rimtsp/article/view/172428/162023 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2020 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2020 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/xml |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e43 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e43 Revista do Instituto de Medicina Tropical de São Paulo; v. 62 (2020); e43 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
_version_ |
1798951652710940672 |