Hepatobiliary alterations in massive biliary ascariasis: histopathological aspects of an autopsy case
Autor(a) principal: | |
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Data de Publicação: | 1990 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/28717 |
Resumo: | Hepatobiliary alterations found in an autopsy case of massive Biliary Ascariasis, are reported on histological grounds. Severe cholangitis was the main finding, but other changes were also detected, such as pyloric and intestinal metaplasia, hyperplasia of the epithelial lining, with intraductal papillomas and adenomatous proliferation. Remnants of the worm were observed tightly adhered to the epithelium, forming microscopic intrahepatic calculi. Mucopolysaccharides, especially acid, showed to be strongly positive on the luminal border, and in proliferated glands around the ducts. The authors discuss the similarity between such findings and Oriental Cholangiohepatitis, and suggest that inflammation and the presence of the parasitic remnants are responsible for the hyperplastic and metaplastic changes, similarly with what occurs in chlonorchiasis, fascioliasis and schistosomiasis. |
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Hepatobiliary alterations in massive biliary ascariasis: histopathological aspects of an autopsy case Lesões hepatobiliares em ascaridíase biliar maciça: aspectos histopatológicos em um caso de autópsia AscariasisRecurrent Pyogenic CholangitisBile DuctsHelminthic Infection Hepatobiliary alterations found in an autopsy case of massive Biliary Ascariasis, are reported on histological grounds. Severe cholangitis was the main finding, but other changes were also detected, such as pyloric and intestinal metaplasia, hyperplasia of the epithelial lining, with intraductal papillomas and adenomatous proliferation. Remnants of the worm were observed tightly adhered to the epithelium, forming microscopic intrahepatic calculi. Mucopolysaccharides, especially acid, showed to be strongly positive on the luminal border, and in proliferated glands around the ducts. The authors discuss the similarity between such findings and Oriental Cholangiohepatitis, and suggest that inflammation and the presence of the parasitic remnants are responsible for the hyperplastic and metaplastic changes, similarly with what occurs in chlonorchiasis, fascioliasis and schistosomiasis. Os autores apresentam os aspectos histopatológicos encontrados no fígado de um caso de autópsia de Ascaridíase Biliar maciça. A intensa colangite foi o aspecto predominante, mas outras lesões também foram encontradas, tais como metaplasia pilórica e intestinal, hiperplasia epitelial com papilomas intraductais, e por vezes padrão adenomatoso. Restos do helminto foram encontrados fortemente aderidos ao epitélio, sendo intensa a positividade de mucopolissacárides, principalmente ácidos, na borda luminal do epitélio ductal e em glândulas proliferadas ao redor dos ductos. Os autores discutem a semelhança da Ascaridíase Biliar com a Colangio Hepatite Oriental, e sugerem que o processo inflamatório e a presença de restos do verme são responsáveis pelas alterações hiperplásicas e metaplásicas, analogamente ao que ocorre na clonorquíase, fasciolíase e esquistossomose. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1990-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/28717Revista do Instituto de Medicina Tropical de São Paulo; Vol. 32 No. 2 (1990); 91-95 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 32 Núm. 2 (1990); 91-95 Revista do Instituto de Medicina Tropical de São Paulo; v. 32 n. 2 (1990); 91-95 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/28717/30570Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessGayotto, Luiz Carlos da CostaMuszkat, Regina Maria LeitãoSouza, Irene Vieira2012-07-02T01:27:35Zoai:revistas.usp.br:article/28717Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:50:28.149791Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
Hepatobiliary alterations in massive biliary ascariasis: histopathological aspects of an autopsy case Lesões hepatobiliares em ascaridíase biliar maciça: aspectos histopatológicos em um caso de autópsia |
title |
Hepatobiliary alterations in massive biliary ascariasis: histopathological aspects of an autopsy case |
spellingShingle |
Hepatobiliary alterations in massive biliary ascariasis: histopathological aspects of an autopsy case Gayotto, Luiz Carlos da Costa Ascariasis Recurrent Pyogenic Cholangitis Bile Ducts Helminthic Infection |
title_short |
Hepatobiliary alterations in massive biliary ascariasis: histopathological aspects of an autopsy case |
title_full |
Hepatobiliary alterations in massive biliary ascariasis: histopathological aspects of an autopsy case |
title_fullStr |
Hepatobiliary alterations in massive biliary ascariasis: histopathological aspects of an autopsy case |
title_full_unstemmed |
Hepatobiliary alterations in massive biliary ascariasis: histopathological aspects of an autopsy case |
title_sort |
Hepatobiliary alterations in massive biliary ascariasis: histopathological aspects of an autopsy case |
author |
Gayotto, Luiz Carlos da Costa |
author_facet |
Gayotto, Luiz Carlos da Costa Muszkat, Regina Maria Leitão Souza, Irene Vieira |
author_role |
author |
author2 |
Muszkat, Regina Maria Leitão Souza, Irene Vieira |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Gayotto, Luiz Carlos da Costa Muszkat, Regina Maria Leitão Souza, Irene Vieira |
dc.subject.por.fl_str_mv |
Ascariasis Recurrent Pyogenic Cholangitis Bile Ducts Helminthic Infection |
topic |
Ascariasis Recurrent Pyogenic Cholangitis Bile Ducts Helminthic Infection |
description |
Hepatobiliary alterations found in an autopsy case of massive Biliary Ascariasis, are reported on histological grounds. Severe cholangitis was the main finding, but other changes were also detected, such as pyloric and intestinal metaplasia, hyperplasia of the epithelial lining, with intraductal papillomas and adenomatous proliferation. Remnants of the worm were observed tightly adhered to the epithelium, forming microscopic intrahepatic calculi. Mucopolysaccharides, especially acid, showed to be strongly positive on the luminal border, and in proliferated glands around the ducts. The authors discuss the similarity between such findings and Oriental Cholangiohepatitis, and suggest that inflammation and the presence of the parasitic remnants are responsible for the hyperplastic and metaplastic changes, similarly with what occurs in chlonorchiasis, fascioliasis and schistosomiasis. |
publishDate |
1990 |
dc.date.none.fl_str_mv |
1990-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/28717 |
url |
https://www.revistas.usp.br/rimtsp/article/view/28717 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/28717/30570 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 32 No. 2 (1990); 91-95 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 32 Núm. 2 (1990); 91-95 Revista do Instituto de Medicina Tropical de São Paulo; v. 32 n. 2 (1990); 91-95 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
_version_ |
1798951638301409280 |