Integrated vector management targeting Anopheles darlingi populations decreases malaria incidence in an unstable transmission area, in the rural Brazilian Amazon

Detalhes bibliográficos
Autor(a) principal: Martins-Campos, Keillen M.
Data de Publicação: 2012
Outros Autores: Pinheiro, Waléria Dasso, Vítor-Silva, Sheila, Siqueira, Andre M., Melo, Gisely Cardoso de, Rodrigues, Íria C., Fé, Nelson Ferreira, Barbosa, Maria das Graças Vale, Tadei, Wanderli Pedro, Guinovart, Caterina, Bassat, Quique, Alonso, Pedro Luís, Lacerda, Marcus V. G., Monteiro, Wuelton Marcelo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional do INPA
Texto Completo: https://repositorio.inpa.gov.br/handle/1/16104
Resumo: Background: Studies on vector behaviour should be conducted in order to evaluate the effectiveness of vector control measures on malaria protection in endemic areas of Latin America, where P. vivax predominates. This work aims to investigate the fauna of anopheline mosquitoes and verify the impact of integrated vector management in two colonization projects in the Careiro Municipality, Western Brazilian Amazon. Methods. Four mosquitoes captures were carried out from August 2008 to March 2010, with an interval of six months between each collection. Since September 2009 a large programme to reduce the burden of malaria has started in the two communities by distribution of insecticide-treated bed nets (ITN) and intensification of indoor residual spraying (IRS). Human biting rates (HBRs), entomological inoculation rates (EIRs), malaria incidence rate (MIR) and Plasmodium carriers prevalence were used as outcomes to estimate the impact of the control measures. Results: A total of 3,189 anophelines were collected, belonging to 13 species. Anopheles darlingi was the predominant species in the period (42.6%), followed by Anopheles albitarsis (38.4%). An. darlingi HBRs showed a notable decreasing trend from the start to the end of the study. Conversely, An. albitarsis increased its contribution to overall HBRs throughout the study. For An. darlingi there was a significant positive correlation between HBRs and MIR (p=0.002). Anopheles albitarsis HBRs showed a significant negative correlation with the corresponding MIR (p=0.045). EIR from total anophelines and from An. darlingi and An. albitarsis presented decreasing patterns in the successive collections. Four species of anophelines (An. darlingi, An. albitarsis, Anopheles braziliensis and Anopheles nuneztovari) were naturally infected with Plasmodium, albeit at very low infection rates. There were a decrease in the MIR for both vivax and falciparum malaria and in the prevalence of Plasmodium vivax and Plasmodium falciparum carriers during the period of study. Conclusions: There is strong evidence of association between the density of An. darlingi and the incidence of malaria in the studies sites, further highlighting the importance of this vector in malaria transmission in this region. An. darlingi susceptibility to control using ITN and IRS is likely to be high in the rural settlements studied. © 2012 Martins-Campos et al.
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spelling Martins-Campos, Keillen M.Pinheiro, Waléria DassoVítor-Silva, SheilaSiqueira, Andre M.Melo, Gisely Cardoso deRodrigues, Íria C.Fé, Nelson FerreiraBarbosa, Maria das Graças ValeTadei, Wanderli PedroGuinovart, CaterinaBassat, QuiqueAlonso, Pedro LuísLacerda, Marcus V. G.Monteiro, Wuelton Marcelo2020-05-24T21:19:38Z2020-05-24T21:19:38Z2012https://repositorio.inpa.gov.br/handle/1/1610410.1186/1475-2875-11-351Background: Studies on vector behaviour should be conducted in order to evaluate the effectiveness of vector control measures on malaria protection in endemic areas of Latin America, where P. vivax predominates. This work aims to investigate the fauna of anopheline mosquitoes and verify the impact of integrated vector management in two colonization projects in the Careiro Municipality, Western Brazilian Amazon. Methods. Four mosquitoes captures were carried out from August 2008 to March 2010, with an interval of six months between each collection. Since September 2009 a large programme to reduce the burden of malaria has started in the two communities by distribution of insecticide-treated bed nets (ITN) and intensification of indoor residual spraying (IRS). Human biting rates (HBRs), entomological inoculation rates (EIRs), malaria incidence rate (MIR) and Plasmodium carriers prevalence were used as outcomes to estimate the impact of the control measures. Results: A total of 3,189 anophelines were collected, belonging to 13 species. Anopheles darlingi was the predominant species in the period (42.6%), followed by Anopheles albitarsis (38.4%). An. darlingi HBRs showed a notable decreasing trend from the start to the end of the study. Conversely, An. albitarsis increased its contribution to overall HBRs throughout the study. For An. darlingi there was a significant positive correlation between HBRs and MIR (p=0.002). Anopheles albitarsis HBRs showed a significant negative correlation with the corresponding MIR (p=0.045). EIR from total anophelines and from An. darlingi and An. albitarsis presented decreasing patterns in the successive collections. Four species of anophelines (An. darlingi, An. albitarsis, Anopheles braziliensis and Anopheles nuneztovari) were naturally infected with Plasmodium, albeit at very low infection rates. There were a decrease in the MIR for both vivax and falciparum malaria and in the prevalence of Plasmodium vivax and Plasmodium falciparum carriers during the period of study. Conclusions: There is strong evidence of association between the density of An. darlingi and the incidence of malaria in the studies sites, further highlighting the importance of this vector in malaria transmission in this region. An. darlingi susceptibility to control using ITN and IRS is likely to be high in the rural settlements studied. © 2012 Martins-Campos et al.Volume 11Attribution-NonCommercial-NoDerivs 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-nd/3.0/br/info:eu-repo/semantics/openAccessInsecticideInsecticideAnophelesAnopheles AlbitarsisAnopheles BraziliensisAnopheles DarlingiAnopheles NuneztovariBed NetBiteBrasilChemical Pest ControlDisease CarrierDisease TransmissionHumanIndoor Residual SprayingInfection RateInoculationMalariaMosquitoPlasmodiumPlasmodium FalciparumPlasmodium VivaxPrevalenceAnimalsBrasilClassificationDrug EffectGrowth, Development And AgingHealth Services ResearchHeterozygoteIncidenceMethodologyMosquitoRural PopulationUtilization ReviewAnimalAnophelesBrasilCarrier StateHealth Services ResearchHumansIncidenceInsecticide-treated BednetsInsecticidesMalariaMosquito ControlRural PopulationIntegrated vector management targeting Anopheles darlingi populations decreases malaria incidence in an unstable transmission area, in the rural Brazilian Amazoninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleMalaria Journalengreponame:Repositório Institucional do INPAinstname:Instituto Nacional de Pesquisas da Amazônia (INPA)instacron:INPAORIGINALartigo-inpa.pdfartigo-inpa.pdfapplication/pdf1347686https://repositorio.inpa.gov.br/bitstream/1/16104/1/artigo-inpa.pdf0ebd8995d489bda9de75e44842bf784bMD511/161042020-05-24 17:25:44.979oai:repositorio:1/16104Repositório de PublicaçõesPUBhttps://repositorio.inpa.gov.br/oai/requestopendoar:2020-05-24T21:25:44Repositório Institucional do INPA - Instituto Nacional de Pesquisas da Amazônia (INPA)false
dc.title.en.fl_str_mv Integrated vector management targeting Anopheles darlingi populations decreases malaria incidence in an unstable transmission area, in the rural Brazilian Amazon
title Integrated vector management targeting Anopheles darlingi populations decreases malaria incidence in an unstable transmission area, in the rural Brazilian Amazon
spellingShingle Integrated vector management targeting Anopheles darlingi populations decreases malaria incidence in an unstable transmission area, in the rural Brazilian Amazon
Martins-Campos, Keillen M.
Insecticide
Insecticide
Anopheles
Anopheles Albitarsis
Anopheles Braziliensis
Anopheles Darlingi
Anopheles Nuneztovari
Bed Net
Bite
Brasil
Chemical Pest Control
Disease Carrier
Disease Transmission
Human
Indoor Residual Spraying
Infection Rate
Inoculation
Malaria
Mosquito
Plasmodium
Plasmodium Falciparum
Plasmodium Vivax
Prevalence
Animals
Brasil
Classification
Drug Effect
Growth, Development And Aging
Health Services Research
Heterozygote
Incidence
Methodology
Mosquito
Rural Population
Utilization Review
Animal
Anopheles
Brasil
Carrier State
Health Services Research
Humans
Incidence
Insecticide-treated Bednets
Insecticides
Malaria
Mosquito Control
Rural Population
title_short Integrated vector management targeting Anopheles darlingi populations decreases malaria incidence in an unstable transmission area, in the rural Brazilian Amazon
title_full Integrated vector management targeting Anopheles darlingi populations decreases malaria incidence in an unstable transmission area, in the rural Brazilian Amazon
title_fullStr Integrated vector management targeting Anopheles darlingi populations decreases malaria incidence in an unstable transmission area, in the rural Brazilian Amazon
title_full_unstemmed Integrated vector management targeting Anopheles darlingi populations decreases malaria incidence in an unstable transmission area, in the rural Brazilian Amazon
title_sort Integrated vector management targeting Anopheles darlingi populations decreases malaria incidence in an unstable transmission area, in the rural Brazilian Amazon
author Martins-Campos, Keillen M.
author_facet Martins-Campos, Keillen M.
Pinheiro, Waléria Dasso
Vítor-Silva, Sheila
Siqueira, Andre M.
Melo, Gisely Cardoso de
Rodrigues, Íria C.
Fé, Nelson Ferreira
Barbosa, Maria das Graças Vale
Tadei, Wanderli Pedro
Guinovart, Caterina
Bassat, Quique
Alonso, Pedro Luís
Lacerda, Marcus V. G.
Monteiro, Wuelton Marcelo
author_role author
author2 Pinheiro, Waléria Dasso
Vítor-Silva, Sheila
Siqueira, Andre M.
Melo, Gisely Cardoso de
Rodrigues, Íria C.
Fé, Nelson Ferreira
Barbosa, Maria das Graças Vale
Tadei, Wanderli Pedro
Guinovart, Caterina
Bassat, Quique
Alonso, Pedro Luís
Lacerda, Marcus V. G.
Monteiro, Wuelton Marcelo
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Martins-Campos, Keillen M.
Pinheiro, Waléria Dasso
Vítor-Silva, Sheila
Siqueira, Andre M.
Melo, Gisely Cardoso de
Rodrigues, Íria C.
Fé, Nelson Ferreira
Barbosa, Maria das Graças Vale
Tadei, Wanderli Pedro
Guinovart, Caterina
Bassat, Quique
Alonso, Pedro Luís
Lacerda, Marcus V. G.
Monteiro, Wuelton Marcelo
dc.subject.eng.fl_str_mv Insecticide
Insecticide
Anopheles
Anopheles Albitarsis
Anopheles Braziliensis
Anopheles Darlingi
Anopheles Nuneztovari
Bed Net
Bite
Brasil
Chemical Pest Control
Disease Carrier
Disease Transmission
Human
Indoor Residual Spraying
Infection Rate
Inoculation
Malaria
Mosquito
Plasmodium
Plasmodium Falciparum
Plasmodium Vivax
Prevalence
Animals
Brasil
Classification
Drug Effect
Growth, Development And Aging
Health Services Research
Heterozygote
Incidence
Methodology
Mosquito
Rural Population
Utilization Review
Animal
Anopheles
Brasil
Carrier State
Health Services Research
Humans
Incidence
Insecticide-treated Bednets
Insecticides
Malaria
Mosquito Control
Rural Population
topic Insecticide
Insecticide
Anopheles
Anopheles Albitarsis
Anopheles Braziliensis
Anopheles Darlingi
Anopheles Nuneztovari
Bed Net
Bite
Brasil
Chemical Pest Control
Disease Carrier
Disease Transmission
Human
Indoor Residual Spraying
Infection Rate
Inoculation
Malaria
Mosquito
Plasmodium
Plasmodium Falciparum
Plasmodium Vivax
Prevalence
Animals
Brasil
Classification
Drug Effect
Growth, Development And Aging
Health Services Research
Heterozygote
Incidence
Methodology
Mosquito
Rural Population
Utilization Review
Animal
Anopheles
Brasil
Carrier State
Health Services Research
Humans
Incidence
Insecticide-treated Bednets
Insecticides
Malaria
Mosquito Control
Rural Population
description Background: Studies on vector behaviour should be conducted in order to evaluate the effectiveness of vector control measures on malaria protection in endemic areas of Latin America, where P. vivax predominates. This work aims to investigate the fauna of anopheline mosquitoes and verify the impact of integrated vector management in two colonization projects in the Careiro Municipality, Western Brazilian Amazon. Methods. Four mosquitoes captures were carried out from August 2008 to March 2010, with an interval of six months between each collection. Since September 2009 a large programme to reduce the burden of malaria has started in the two communities by distribution of insecticide-treated bed nets (ITN) and intensification of indoor residual spraying (IRS). Human biting rates (HBRs), entomological inoculation rates (EIRs), malaria incidence rate (MIR) and Plasmodium carriers prevalence were used as outcomes to estimate the impact of the control measures. Results: A total of 3,189 anophelines were collected, belonging to 13 species. Anopheles darlingi was the predominant species in the period (42.6%), followed by Anopheles albitarsis (38.4%). An. darlingi HBRs showed a notable decreasing trend from the start to the end of the study. Conversely, An. albitarsis increased its contribution to overall HBRs throughout the study. For An. darlingi there was a significant positive correlation between HBRs and MIR (p=0.002). Anopheles albitarsis HBRs showed a significant negative correlation with the corresponding MIR (p=0.045). EIR from total anophelines and from An. darlingi and An. albitarsis presented decreasing patterns in the successive collections. Four species of anophelines (An. darlingi, An. albitarsis, Anopheles braziliensis and Anopheles nuneztovari) were naturally infected with Plasmodium, albeit at very low infection rates. There were a decrease in the MIR for both vivax and falciparum malaria and in the prevalence of Plasmodium vivax and Plasmodium falciparum carriers during the period of study. Conclusions: There is strong evidence of association between the density of An. darlingi and the incidence of malaria in the studies sites, further highlighting the importance of this vector in malaria transmission in this region. An. darlingi susceptibility to control using ITN and IRS is likely to be high in the rural settlements studied. © 2012 Martins-Campos et al.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2020-05-24T21:19:38Z
dc.date.available.fl_str_mv 2020-05-24T21:19:38Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://repositorio.inpa.gov.br/handle/1/16104
dc.identifier.doi.none.fl_str_mv 10.1186/1475-2875-11-351
url https://repositorio.inpa.gov.br/handle/1/16104
identifier_str_mv 10.1186/1475-2875-11-351
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Volume 11
dc.rights.driver.fl_str_mv Attribution-NonCommercial-NoDerivs 3.0 Brazil
http://creativecommons.org/licenses/by-nc-nd/3.0/br/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivs 3.0 Brazil
http://creativecommons.org/licenses/by-nc-nd/3.0/br/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Malaria Journal
publisher.none.fl_str_mv Malaria Journal
dc.source.none.fl_str_mv reponame:Repositório Institucional do INPA
instname:Instituto Nacional de Pesquisas da Amazônia (INPA)
instacron:INPA
instname_str Instituto Nacional de Pesquisas da Amazônia (INPA)
instacron_str INPA
institution INPA
reponame_str Repositório Institucional do INPA
collection Repositório Institucional do INPA
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