Hemochromatosis-like disease in Brazilian tapirs (Tapirus terrestris) in Pará state, Brazil
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Acta Amazonica |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672022000400303 |
Resumo: | ABSTRACT We report two cases of hemochromatosis-like disease in captive Brazilian tapirs, Tapirus terrestris in Pará state, Brazil. Both animals presented symptoms of chronic hepatopathy associated with marked accumulation of hemosiderin. The coloration of Perls demonstrated pronounced iron accumulation in macrophages in the portal space, Kupffer cells, and, to a lesser extent, in the hepatocytes of the periportal region. Marked portal fibrosis was evidenced by Masson’s trichrome. The pathological mechanisms of this disease in tapirs are not yet well established. It has been suggested that the species may have different mechanisms of iron absorption and elimination, rendering them sensitive to elevation in dietary levels of this metal. Two previous reports of this disease in T. terrestris exist from zoos in Australia and Scotland. This is the first report of this disease in tapirs in Brazil based on histopathological and histochemical findings. |
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Hemochromatosis-like disease in Brazilian tapirs (Tapirus terrestris) in Pará state, BrazilhepatopathyhemosiderinPerissodactylaAmazoniaABSTRACT We report two cases of hemochromatosis-like disease in captive Brazilian tapirs, Tapirus terrestris in Pará state, Brazil. Both animals presented symptoms of chronic hepatopathy associated with marked accumulation of hemosiderin. The coloration of Perls demonstrated pronounced iron accumulation in macrophages in the portal space, Kupffer cells, and, to a lesser extent, in the hepatocytes of the periportal region. Marked portal fibrosis was evidenced by Masson’s trichrome. The pathological mechanisms of this disease in tapirs are not yet well established. It has been suggested that the species may have different mechanisms of iron absorption and elimination, rendering them sensitive to elevation in dietary levels of this metal. Two previous reports of this disease in T. terrestris exist from zoos in Australia and Scotland. This is the first report of this disease in tapirs in Brazil based on histopathological and histochemical findings.Instituto Nacional de Pesquisas da Amazônia2022-12-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672022000400303Acta Amazonica v.52 n.4 2022reponame:Acta Amazonicainstname:Instituto Nacional de Pesquisas da Amazônia (INPA)instacron:INPA10.1590/1809-4392202103581info:eu-repo/semantics/openAccessLIMA,Adrielli Heloise dos AnjosNETO,Américo MeirellesCARDOSO,Rosekelly de JesusSARMENTO,Natalia Maxine F. P.OLIVEIRA,Arieli Sousa deMOURA,Márcio Alan OliveiraGONZALEZ,Gerson Bladimir EscobarRIET-CORREA,GabrielaSOARES,Manoel Ananis LopesBEZERRA JUNIOR,Pedro SoaresAMARAL,Alessandra ScofieldCERQUEIRA,Valíria Duarteeng2022-11-30T00:00:00Zoai:scielo:S0044-59672022000400303Revistahttps://acta.inpa.gov.br/PUBhttps://old.scielo.br/oai/scielo-oai.phpacta@inpa.gov.br||acta@inpa.gov.br1809-43920044-5967opendoar:2022-11-30T00:00Acta Amazonica - Instituto Nacional de Pesquisas da Amazônia (INPA)false |
dc.title.none.fl_str_mv |
Hemochromatosis-like disease in Brazilian tapirs (Tapirus terrestris) in Pará state, Brazil |
title |
Hemochromatosis-like disease in Brazilian tapirs (Tapirus terrestris) in Pará state, Brazil |
spellingShingle |
Hemochromatosis-like disease in Brazilian tapirs (Tapirus terrestris) in Pará state, Brazil LIMA,Adrielli Heloise dos Anjos hepatopathy hemosiderin Perissodactyla Amazonia |
title_short |
Hemochromatosis-like disease in Brazilian tapirs (Tapirus terrestris) in Pará state, Brazil |
title_full |
Hemochromatosis-like disease in Brazilian tapirs (Tapirus terrestris) in Pará state, Brazil |
title_fullStr |
Hemochromatosis-like disease in Brazilian tapirs (Tapirus terrestris) in Pará state, Brazil |
title_full_unstemmed |
Hemochromatosis-like disease in Brazilian tapirs (Tapirus terrestris) in Pará state, Brazil |
title_sort |
Hemochromatosis-like disease in Brazilian tapirs (Tapirus terrestris) in Pará state, Brazil |
author |
LIMA,Adrielli Heloise dos Anjos |
author_facet |
LIMA,Adrielli Heloise dos Anjos NETO,Américo Meirelles CARDOSO,Rosekelly de Jesus SARMENTO,Natalia Maxine F. P. OLIVEIRA,Arieli Sousa de MOURA,Márcio Alan Oliveira GONZALEZ,Gerson Bladimir Escobar RIET-CORREA,Gabriela SOARES,Manoel Ananis Lopes BEZERRA JUNIOR,Pedro Soares AMARAL,Alessandra Scofield CERQUEIRA,Valíria Duarte |
author_role |
author |
author2 |
NETO,Américo Meirelles CARDOSO,Rosekelly de Jesus SARMENTO,Natalia Maxine F. P. OLIVEIRA,Arieli Sousa de MOURA,Márcio Alan Oliveira GONZALEZ,Gerson Bladimir Escobar RIET-CORREA,Gabriela SOARES,Manoel Ananis Lopes BEZERRA JUNIOR,Pedro Soares AMARAL,Alessandra Scofield CERQUEIRA,Valíria Duarte |
author2_role |
author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
LIMA,Adrielli Heloise dos Anjos NETO,Américo Meirelles CARDOSO,Rosekelly de Jesus SARMENTO,Natalia Maxine F. P. OLIVEIRA,Arieli Sousa de MOURA,Márcio Alan Oliveira GONZALEZ,Gerson Bladimir Escobar RIET-CORREA,Gabriela SOARES,Manoel Ananis Lopes BEZERRA JUNIOR,Pedro Soares AMARAL,Alessandra Scofield CERQUEIRA,Valíria Duarte |
dc.subject.por.fl_str_mv |
hepatopathy hemosiderin Perissodactyla Amazonia |
topic |
hepatopathy hemosiderin Perissodactyla Amazonia |
description |
ABSTRACT We report two cases of hemochromatosis-like disease in captive Brazilian tapirs, Tapirus terrestris in Pará state, Brazil. Both animals presented symptoms of chronic hepatopathy associated with marked accumulation of hemosiderin. The coloration of Perls demonstrated pronounced iron accumulation in macrophages in the portal space, Kupffer cells, and, to a lesser extent, in the hepatocytes of the periportal region. Marked portal fibrosis was evidenced by Masson’s trichrome. The pathological mechanisms of this disease in tapirs are not yet well established. It has been suggested that the species may have different mechanisms of iron absorption and elimination, rendering them sensitive to elevation in dietary levels of this metal. Two previous reports of this disease in T. terrestris exist from zoos in Australia and Scotland. This is the first report of this disease in tapirs in Brazil based on histopathological and histochemical findings. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672022000400303 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672022000400303 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1809-4392202103581 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Nacional de Pesquisas da Amazônia |
publisher.none.fl_str_mv |
Instituto Nacional de Pesquisas da Amazônia |
dc.source.none.fl_str_mv |
Acta Amazonica v.52 n.4 2022 reponame:Acta Amazonica instname:Instituto Nacional de Pesquisas da Amazônia (INPA) instacron:INPA |
instname_str |
Instituto Nacional de Pesquisas da Amazônia (INPA) |
instacron_str |
INPA |
institution |
INPA |
reponame_str |
Acta Amazonica |
collection |
Acta Amazonica |
repository.name.fl_str_mv |
Acta Amazonica - Instituto Nacional de Pesquisas da Amazônia (INPA) |
repository.mail.fl_str_mv |
acta@inpa.gov.br||acta@inpa.gov.br |
_version_ |
1752129841628446720 |