Antinociceptive action of Light Emitting Diode in an experimental model with hyperalgesia by capsaicin

• Autor(a) principal: Kerppers,Ivo Ilvan
• Data de Publicação: 2014
• Outros Autores: Paz,Isabel de Almeida, Pires,Juliana Aparecida Wosch, Ribeiro,Larissa Gulogurski, Rolão,Marcos Paulo Polowei, Furmann,Meiriélly, Oliveira,Thais Barbosa de, Eltchechem,Camila da Luz, Pereira,Mario César da Silva, Fréz,Andersom Ricardo
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: MedicalExpress (São Paulo. Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2358-04292014000500268
• topic: Light Emitting Diode; nociception; pain measurement

OBJECTIVE: To assess the antinociceptive effect of a light emitting diode (LED) in the acute phase of pain induced by capsaicin. METHOD: Twelve Wistar rats were used, divided into a control and an experimental group. The pain process was induced in both groups by applying 50 microliters of a 2% capsaicin solution in the plantar region of the right hind limb. In the experimental group, a single application of LED 627nm (70mw, 7 Joules/cm2 dose) was also applied. Nociception was assessed 30 minutes and 24 hours after LED application using a digital analgesymeter (Von Frey). RESULTS: Twenty four hours after irradiation, an increase in the nociceptive threshold was observed in the LED group in comparison to the 30 min level, as well as in the inter-group comparison. CONCLUSIONS: The use of LED can be considered as a non-invasive analgesic method as it increases of the nociceptive threshold 24 hours after pain is induced.