Possible solutions to the shortcomings of the Yale-Brown Obsessive-Compulsive Scale

Detalhes bibliográficos
Autor(a) principal: Diniz,Juliana
Data de Publicação: 2015
Outros Autores: Fossaluza,Victor, Belotto-Silva,Cristina, Shavitt,Roseli Gedanke, Pereira,Carlos Alberto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: MedicalExpress (São Paulo. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2358-04292015000400003
Resumo: OBJECTIVE: The Yale-Brown Obsessive-Compulsive Scale is the most frequently used instrument to measure obsessive-compulsive symptom severity. We describe its shortcomings and propose new methods of evaluating current severity and treatment response. METHOD: The Yale-Brown Obsessive-Compulsive Scale total and subscale scores were pooled from one cross-sectional study database containing information on 1,000 obsessive-compulsive disorder patients from seven specialized mental health care centers. Additional longitudinal data were pooled for 155 patients who participated in a 12-week trial that evaluated the effectiveness of fluoxetine vs. cognitive-behavior therapy as first-line treatment options. All patients were followed by a clinician who provided a clinical opinion of improvement. Neither patients nor clinicians were aware of the classifications proposed in this study. New methods for using the severity scores were compared with the clinical opinion of improvement. RESULTS: In the Yale-Brown Obsessive-compulsive scale, the summing-up of subscale scores to compose a total score does not accurately reflect clinical severity. In addition, the reduction of scores with treatment does not usually reach score zero in either subscale. To overcome such problems, we suggest (a) use of the maximum score of any of the subscales; (b) use of a minimum score of 4 in each subscale or 5 for the maximum in any subscale as the goal after treatment. This method performed better than traditional ones regarding sensitivity and specificity against the gold standard represented by the clinical opinion of improvement. CONCLUSION: The new proposed response criteria are coherent with the clinical opinion of improvement and perform better than the traditional methodology.
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spelling Possible solutions to the shortcomings of the Yale-Brown Obsessive-Compulsive ScaleObsessive/compulsive disorderClinical trialsObsessive/compulsive disorder evaluationInstruments OBJECTIVE: The Yale-Brown Obsessive-Compulsive Scale is the most frequently used instrument to measure obsessive-compulsive symptom severity. We describe its shortcomings and propose new methods of evaluating current severity and treatment response. METHOD: The Yale-Brown Obsessive-Compulsive Scale total and subscale scores were pooled from one cross-sectional study database containing information on 1,000 obsessive-compulsive disorder patients from seven specialized mental health care centers. Additional longitudinal data were pooled for 155 patients who participated in a 12-week trial that evaluated the effectiveness of fluoxetine vs. cognitive-behavior therapy as first-line treatment options. All patients were followed by a clinician who provided a clinical opinion of improvement. Neither patients nor clinicians were aware of the classifications proposed in this study. New methods for using the severity scores were compared with the clinical opinion of improvement. RESULTS: In the Yale-Brown Obsessive-compulsive scale, the summing-up of subscale scores to compose a total score does not accurately reflect clinical severity. In addition, the reduction of scores with treatment does not usually reach score zero in either subscale. To overcome such problems, we suggest (a) use of the maximum score of any of the subscales; (b) use of a minimum score of 4 in each subscale or 5 for the maximum in any subscale as the goal after treatment. This method performed better than traditional ones regarding sensitivity and specificity against the gold standard represented by the clinical opinion of improvement. CONCLUSION: The new proposed response criteria are coherent with the clinical opinion of improvement and perform better than the traditional methodology.Mavera Edições Técnicas e Científicas Ltda2015-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2358-04292015000400003MedicalExpress v.2 n.4 2015reponame:MedicalExpress (São Paulo. Online)instname:Mavera Edições Científicas e Técnicas Ltda-MEinstacron:METC10.5935/MedicalExpress.2015.04.03info:eu-repo/semantics/openAccessDiniz,JulianaFossaluza,VictorBelotto-Silva,CristinaShavitt,Roseli GedankePereira,Carlos Albertoeng2016-03-08T00:00:00Zoai:scielo:S2358-04292015000400003Revistahttp://www.medicalexpress.net.brhttps://old.scielo.br/oai/scielo-oai.php||medicalexpress@me.net.br2358-04292318-8111opendoar:2016-03-08T00:00MedicalExpress (São Paulo. Online) - Mavera Edições Científicas e Técnicas Ltda-MEfalse
dc.title.none.fl_str_mv Possible solutions to the shortcomings of the Yale-Brown Obsessive-Compulsive Scale
title Possible solutions to the shortcomings of the Yale-Brown Obsessive-Compulsive Scale
spellingShingle Possible solutions to the shortcomings of the Yale-Brown Obsessive-Compulsive Scale
Diniz,Juliana
Obsessive/compulsive disorder
Clinical trials
Obsessive/compulsive disorder evaluation
Instruments
title_short Possible solutions to the shortcomings of the Yale-Brown Obsessive-Compulsive Scale
title_full Possible solutions to the shortcomings of the Yale-Brown Obsessive-Compulsive Scale
title_fullStr Possible solutions to the shortcomings of the Yale-Brown Obsessive-Compulsive Scale
title_full_unstemmed Possible solutions to the shortcomings of the Yale-Brown Obsessive-Compulsive Scale
title_sort Possible solutions to the shortcomings of the Yale-Brown Obsessive-Compulsive Scale
author Diniz,Juliana
author_facet Diniz,Juliana
Fossaluza,Victor
Belotto-Silva,Cristina
Shavitt,Roseli Gedanke
Pereira,Carlos Alberto
author_role author
author2 Fossaluza,Victor
Belotto-Silva,Cristina
Shavitt,Roseli Gedanke
Pereira,Carlos Alberto
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Diniz,Juliana
Fossaluza,Victor
Belotto-Silva,Cristina
Shavitt,Roseli Gedanke
Pereira,Carlos Alberto
dc.subject.por.fl_str_mv Obsessive/compulsive disorder
Clinical trials
Obsessive/compulsive disorder evaluation
Instruments
topic Obsessive/compulsive disorder
Clinical trials
Obsessive/compulsive disorder evaluation
Instruments
description OBJECTIVE: The Yale-Brown Obsessive-Compulsive Scale is the most frequently used instrument to measure obsessive-compulsive symptom severity. We describe its shortcomings and propose new methods of evaluating current severity and treatment response. METHOD: The Yale-Brown Obsessive-Compulsive Scale total and subscale scores were pooled from one cross-sectional study database containing information on 1,000 obsessive-compulsive disorder patients from seven specialized mental health care centers. Additional longitudinal data were pooled for 155 patients who participated in a 12-week trial that evaluated the effectiveness of fluoxetine vs. cognitive-behavior therapy as first-line treatment options. All patients were followed by a clinician who provided a clinical opinion of improvement. Neither patients nor clinicians were aware of the classifications proposed in this study. New methods for using the severity scores were compared with the clinical opinion of improvement. RESULTS: In the Yale-Brown Obsessive-compulsive scale, the summing-up of subscale scores to compose a total score does not accurately reflect clinical severity. In addition, the reduction of scores with treatment does not usually reach score zero in either subscale. To overcome such problems, we suggest (a) use of the maximum score of any of the subscales; (b) use of a minimum score of 4 in each subscale or 5 for the maximum in any subscale as the goal after treatment. This method performed better than traditional ones regarding sensitivity and specificity against the gold standard represented by the clinical opinion of improvement. CONCLUSION: The new proposed response criteria are coherent with the clinical opinion of improvement and perform better than the traditional methodology.
publishDate 2015
dc.date.none.fl_str_mv 2015-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv 10.5935/MedicalExpress.2015.04.03
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dc.publisher.none.fl_str_mv Mavera Edições Técnicas e Científicas Ltda
publisher.none.fl_str_mv Mavera Edições Técnicas e Científicas Ltda
dc.source.none.fl_str_mv MedicalExpress v.2 n.4 2015
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reponame_str MedicalExpress (São Paulo. Online)
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