Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in mice
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Psychology & Neuroscience (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882010000200015 |
Resumo: | Nepeta cataria (catnip) is a plant used in pet toys and to treat human diseases. Catnip has also been used in the treatment of some depressive disorders. In this paper, we studied the antidepressant, anxiogenic, and motor activity effects of acute and repeated feeding of chow enriched with 10% N. cataria leaves and the acute and repeated administration of apolar and polar extracts of N. cataria leaves in male mice. The results showed that repeated feeding and acute and repeated administration with the apolar extract reduced immobility in the behavioral despair test but did not alter elevated plus maze and open-field parameters. Acute feeding and the acute and repeated administration of the polar extracts of N. cataria leaves did not alter the behavior of mice. These data suggest that N. cataria has antidepressant properties. Moreover, this antidepressant activity was present in the apolar extract. |
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Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in miceopen fieldelevated plus mazebehavioral despair testNepeta cataria (catnip) is a plant used in pet toys and to treat human diseases. Catnip has also been used in the treatment of some depressive disorders. In this paper, we studied the antidepressant, anxiogenic, and motor activity effects of acute and repeated feeding of chow enriched with 10% N. cataria leaves and the acute and repeated administration of apolar and polar extracts of N. cataria leaves in male mice. The results showed that repeated feeding and acute and repeated administration with the apolar extract reduced immobility in the behavioral despair test but did not alter elevated plus maze and open-field parameters. Acute feeding and the acute and repeated administration of the polar extracts of N. cataria leaves did not alter the behavior of mice. These data suggest that N. cataria has antidepressant properties. Moreover, this antidepressant activity was present in the apolar extract.Pontificia Universidade Católica do Rio de JaneiroUniversidade de BrasíliaUniversidade de São Paulo2010-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882010000200015Psychology & Neuroscience v.3 n.2 2010reponame:Psychology & Neuroscience (Online)instname:Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)instacron:PUCRJ10.3922/j.psns.2010.2.015info:eu-repo/semantics/openAccessBernardi,Maria MarthaKirsten,Thiago BertiSalzgeber,Simone AngélicaRicci,Esther LopesRomoff,PauleteLago,João Henrique GuilardiLourenço,Lygia Mendeseng2011-03-21T00:00:00Zoai:scielo:S1983-32882010000200015Revistahttps://www.apa.org/pubs/journals/pnePRIhttps://old.scielo.br/oai/scielo-oai.phppsycneuro@psycneuro.org1983-32881984-3054opendoar:2011-03-21T00:00Psychology & Neuroscience (Online) - Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)false |
dc.title.none.fl_str_mv |
Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in mice |
title |
Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in mice |
spellingShingle |
Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in mice Bernardi,Maria Martha open field elevated plus maze behavioral despair test |
title_short |
Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in mice |
title_full |
Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in mice |
title_fullStr |
Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in mice |
title_full_unstemmed |
Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in mice |
title_sort |
Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in mice |
author |
Bernardi,Maria Martha |
author_facet |
Bernardi,Maria Martha Kirsten,Thiago Berti Salzgeber,Simone Angélica Ricci,Esther Lopes Romoff,Paulete Lago,João Henrique Guilardi Lourenço,Lygia Mendes |
author_role |
author |
author2 |
Kirsten,Thiago Berti Salzgeber,Simone Angélica Ricci,Esther Lopes Romoff,Paulete Lago,João Henrique Guilardi Lourenço,Lygia Mendes |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Bernardi,Maria Martha Kirsten,Thiago Berti Salzgeber,Simone Angélica Ricci,Esther Lopes Romoff,Paulete Lago,João Henrique Guilardi Lourenço,Lygia Mendes |
dc.subject.por.fl_str_mv |
open field elevated plus maze behavioral despair test |
topic |
open field elevated plus maze behavioral despair test |
description |
Nepeta cataria (catnip) is a plant used in pet toys and to treat human diseases. Catnip has also been used in the treatment of some depressive disorders. In this paper, we studied the antidepressant, anxiogenic, and motor activity effects of acute and repeated feeding of chow enriched with 10% N. cataria leaves and the acute and repeated administration of apolar and polar extracts of N. cataria leaves in male mice. The results showed that repeated feeding and acute and repeated administration with the apolar extract reduced immobility in the behavioral despair test but did not alter elevated plus maze and open-field parameters. Acute feeding and the acute and repeated administration of the polar extracts of N. cataria leaves did not alter the behavior of mice. These data suggest that N. cataria has antidepressant properties. Moreover, this antidepressant activity was present in the apolar extract. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882010000200015 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882010000200015 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.3922/j.psns.2010.2.015 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Pontificia Universidade Católica do Rio de Janeiro Universidade de Brasília Universidade de São Paulo |
publisher.none.fl_str_mv |
Pontificia Universidade Católica do Rio de Janeiro Universidade de Brasília Universidade de São Paulo |
dc.source.none.fl_str_mv |
Psychology & Neuroscience v.3 n.2 2010 reponame:Psychology & Neuroscience (Online) instname:Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC) instacron:PUCRJ |
instname_str |
Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC) |
instacron_str |
PUCRJ |
institution |
PUCRJ |
reponame_str |
Psychology & Neuroscience (Online) |
collection |
Psychology & Neuroscience (Online) |
repository.name.fl_str_mv |
Psychology & Neuroscience (Online) - Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC) |
repository.mail.fl_str_mv |
psycneuro@psycneuro.org |
_version_ |
1754821072391241728 |