Oxidative profile of patients with osteoarthrosis undergoing total knee arthroplasty
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Fisioterapia em Movimento |
Texto Completo: | https://periodicos.pucpr.br/fisio/article/view/21654 |
Resumo: | Introduction: Total knee arthroplasty may be the most appropriate method of treatment in several cases of osteoarthritis. This disease causes tissue damage, which is closely related to the production of free radicals, leading to oxidative stress and to lipid damage. Because of that, the body has several antioxidative defense systems involved in detoxification (antioxidants). Objective: Based on the previous information, the goal of this study was to establish the systemic and local oxidative profile of individuals with osteoarthritis submitted to total knee arthroplasty. Materials and methods: The sample consisted of four female patients (65.5 ± 0.7 years) with osteoarthritis of the knee. Blood and synovial fluid (SF) samples were collected from the patients 15 minutes before surgery. The concentrations of flavonoids, catalase, and TBARS were then quantified. Results: The results indicate a higher catalase activity in the SF than in the serum (S), (SF = 1 S = 14.3 ± 3.1 ± 0.8). The concentration of TBARS proved to be higher in the SF (SF = 0.29 ± 0.02 S = 0.09 ± 0.05), whereas the concentration of phenols was higher in the serum (SF = 3.2 S = 5.2 ± 0.2 ± 0.6). Conclusion: Osteoarthritis is a disease that increases the oxidative stress markers in the serum and in the SF. |
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Fisioterapia em Movimento |
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Oxidative profile of patients with osteoarthrosis undergoing total knee arthroplastyIntroduction: Total knee arthroplasty may be the most appropriate method of treatment in several cases of osteoarthritis. This disease causes tissue damage, which is closely related to the production of free radicals, leading to oxidative stress and to lipid damage. Because of that, the body has several antioxidative defense systems involved in detoxification (antioxidants). Objective: Based on the previous information, the goal of this study was to establish the systemic and local oxidative profile of individuals with osteoarthritis submitted to total knee arthroplasty. Materials and methods: The sample consisted of four female patients (65.5 ± 0.7 years) with osteoarthritis of the knee. Blood and synovial fluid (SF) samples were collected from the patients 15 minutes before surgery. The concentrations of flavonoids, catalase, and TBARS were then quantified. Results: The results indicate a higher catalase activity in the SF than in the serum (S), (SF = 1 S = 14.3 ± 3.1 ± 0.8). The concentration of TBARS proved to be higher in the SF (SF = 0.29 ± 0.02 S = 0.09 ± 0.05), whereas the concentration of phenols was higher in the serum (SF = 3.2 S = 5.2 ± 0.2 ± 0.6). Conclusion: Osteoarthritis is a disease that increases the oxidative stress markers in the serum and in the SF.Editora PUCPRESS2017-09-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.pucpr.br/fisio/article/view/2165410.1590/0103-5150.027.002.AO01Fisioterapia em Movimento (Physical Therapy in Movement); Vol. 27 No. 2 (2014)Fisioterapia em Movimento; v. 27 n. 2 (2014)1980-5918reponame:Fisioterapia em Movimentoinstname:Pontifícia Universidade Católica do Paraná (PUC-PR)instacron:PUC_PRenghttps://periodicos.pucpr.br/fisio/article/view/21654/20775Copyright (c) 2022 PUCPRESSinfo:eu-repo/semantics/openAccessPierezan, BrunaWebber, BrunaVidmar, Marlon Francysde Quadros Martins, César Antôniode Almeida, Carlos Rafaelde Oliveira Siqueira, Luciano2022-03-07T19:01:04Zoai:ojs.periodicos.pucpr.br:article/21654Revistahttps://periodicos.pucpr.br/fisioPRIhttps://periodicos.pucpr.br/fisio/oairubia.farias@pucpr.br||revista.fisioterapia@pucpr.br1980-59180103-5150opendoar:2022-03-07T19:01:04Fisioterapia em Movimento - Pontifícia Universidade Católica do Paraná (PUC-PR)false |
dc.title.none.fl_str_mv |
Oxidative profile of patients with osteoarthrosis undergoing total knee arthroplasty |
title |
Oxidative profile of patients with osteoarthrosis undergoing total knee arthroplasty |
spellingShingle |
Oxidative profile of patients with osteoarthrosis undergoing total knee arthroplasty Pierezan, Bruna |
title_short |
Oxidative profile of patients with osteoarthrosis undergoing total knee arthroplasty |
title_full |
Oxidative profile of patients with osteoarthrosis undergoing total knee arthroplasty |
title_fullStr |
Oxidative profile of patients with osteoarthrosis undergoing total knee arthroplasty |
title_full_unstemmed |
Oxidative profile of patients with osteoarthrosis undergoing total knee arthroplasty |
title_sort |
Oxidative profile of patients with osteoarthrosis undergoing total knee arthroplasty |
author |
Pierezan, Bruna |
author_facet |
Pierezan, Bruna Webber, Bruna Vidmar, Marlon Francys de Quadros Martins, César Antônio de Almeida, Carlos Rafael de Oliveira Siqueira, Luciano |
author_role |
author |
author2 |
Webber, Bruna Vidmar, Marlon Francys de Quadros Martins, César Antônio de Almeida, Carlos Rafael de Oliveira Siqueira, Luciano |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Pierezan, Bruna Webber, Bruna Vidmar, Marlon Francys de Quadros Martins, César Antônio de Almeida, Carlos Rafael de Oliveira Siqueira, Luciano |
description |
Introduction: Total knee arthroplasty may be the most appropriate method of treatment in several cases of osteoarthritis. This disease causes tissue damage, which is closely related to the production of free radicals, leading to oxidative stress and to lipid damage. Because of that, the body has several antioxidative defense systems involved in detoxification (antioxidants). Objective: Based on the previous information, the goal of this study was to establish the systemic and local oxidative profile of individuals with osteoarthritis submitted to total knee arthroplasty. Materials and methods: The sample consisted of four female patients (65.5 ± 0.7 years) with osteoarthritis of the knee. Blood and synovial fluid (SF) samples were collected from the patients 15 minutes before surgery. The concentrations of flavonoids, catalase, and TBARS were then quantified. Results: The results indicate a higher catalase activity in the SF than in the serum (S), (SF = 1 S = 14.3 ± 3.1 ± 0.8). The concentration of TBARS proved to be higher in the SF (SF = 0.29 ± 0.02 S = 0.09 ± 0.05), whereas the concentration of phenols was higher in the serum (SF = 3.2 S = 5.2 ± 0.2 ± 0.6). Conclusion: Osteoarthritis is a disease that increases the oxidative stress markers in the serum and in the SF. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-09-18 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.pucpr.br/fisio/article/view/21654 10.1590/0103-5150.027.002.AO01 |
url |
https://periodicos.pucpr.br/fisio/article/view/21654 |
identifier_str_mv |
10.1590/0103-5150.027.002.AO01 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://periodicos.pucpr.br/fisio/article/view/21654/20775 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 PUCPRESS info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 PUCPRESS |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Editora PUCPRESS |
publisher.none.fl_str_mv |
Editora PUCPRESS |
dc.source.none.fl_str_mv |
Fisioterapia em Movimento (Physical Therapy in Movement); Vol. 27 No. 2 (2014) Fisioterapia em Movimento; v. 27 n. 2 (2014) 1980-5918 reponame:Fisioterapia em Movimento instname:Pontifícia Universidade Católica do Paraná (PUC-PR) instacron:PUC_PR |
instname_str |
Pontifícia Universidade Católica do Paraná (PUC-PR) |
instacron_str |
PUC_PR |
institution |
PUC_PR |
reponame_str |
Fisioterapia em Movimento |
collection |
Fisioterapia em Movimento |
repository.name.fl_str_mv |
Fisioterapia em Movimento - Pontifícia Universidade Católica do Paraná (PUC-PR) |
repository.mail.fl_str_mv |
rubia.farias@pucpr.br||revista.fisioterapia@pucpr.br |
_version_ |
1799138747119304704 |