Influence of ethanol consumption in salivary glands [Abstract in English]

Detalhes bibliográficos
Autor(a) principal: Carrard, Vinicius Coelho
Data de Publicação: 2008
Outros Autores: Mendez, Marina, Nolde, Josué, Alves, Luciana Duarte, Fossati, Anna Christina Medeiros, Sant'Ana Filho, Manoel
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Scientia Medica (Porto Alegre. Online)
Texto Completo: https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1646
Resumo: Aims: To perform a literature review about alcohol effects on salivary gland. Source of data: Articles were retrieved from Medline data base using the key-words alcohol/ethanol and salivary glands. Summary of findings: Increase in ethanol consumption has been observed in people, and it causes alterations in several systems. Enlargement of salivary glands and salivary flow decrease have been observed in alcoholics. The decreased salivary flow results in increased susceptibility of injuries to the mouth, like those related to caries and periodontitis, because saliva has protective properties. Morphology alterations like adipocytes infiltration, ductal hyperplasia and decrease in acinar cells ratio can be observed. The ethanol consumption reduces salivary flow, and immunoglobulins and antioxidants levels decrease in saliva. Ethanol degradation generates toxic metabolites, like acetaldehyde, that can modify the salivary gland function. There is a possibility that saliva helps on acetaldehyde distribution in the mouth, improving ethanol consumption damage. In addition, other mechanisms are included in this damage like decrease in prostaglandins, malnutrition, immune system alterations and oxidative stress. Oxidative stress may be involved in pathogenesis of several chronicdegenerative diseases, like cancer. Conclusions: The alcoholics must receive a special attention in oral care because its local and systemic conditions improve susceptibility to oral illnesses, such as caries, periodontitis and cancer. KEY WORDS: SALIVARY GLAND/pathology; ETHANOL; ALCOHOL-RELATED DISORDERS ; MOUTH DISEASES; METAANALYSIS.
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spelling Influence of ethanol consumption in salivary glands [Abstract in English]Influência do Consumo de Etanol nas Glândulas SalivaresGlândula SalivarEtanolBocaAims: To perform a literature review about alcohol effects on salivary gland. Source of data: Articles were retrieved from Medline data base using the key-words alcohol/ethanol and salivary glands. Summary of findings: Increase in ethanol consumption has been observed in people, and it causes alterations in several systems. Enlargement of salivary glands and salivary flow decrease have been observed in alcoholics. The decreased salivary flow results in increased susceptibility of injuries to the mouth, like those related to caries and periodontitis, because saliva has protective properties. Morphology alterations like adipocytes infiltration, ductal hyperplasia and decrease in acinar cells ratio can be observed. The ethanol consumption reduces salivary flow, and immunoglobulins and antioxidants levels decrease in saliva. Ethanol degradation generates toxic metabolites, like acetaldehyde, that can modify the salivary gland function. There is a possibility that saliva helps on acetaldehyde distribution in the mouth, improving ethanol consumption damage. In addition, other mechanisms are included in this damage like decrease in prostaglandins, malnutrition, immune system alterations and oxidative stress. Oxidative stress may be involved in pathogenesis of several chronicdegenerative diseases, like cancer. Conclusions: The alcoholics must receive a special attention in oral care because its local and systemic conditions improve susceptibility to oral illnesses, such as caries, periodontitis and cancer. KEY WORDS: SALIVARY GLAND/pathology; ETHANOL; ALCOHOL-RELATED DISORDERS ; MOUTH DISEASES; METAANALYSIS.Objetivos: Realizar uma revisão da literatura sobre os efeitos do consumo de etanol nas glândulas salivares. Fonte de dados: Foi realizada uma busca no banco de dados Medline, utilizando as palavras alcohol/ ethanol, salivary glands. Síntese dos dados: Tem sido observada na população uma elevação no consumo de bebidas alcoólicas pela população, ocasionando alterações em diversos sistemas. Aumento de volume das glândulas salivares e redução do fluxo salivar são freqüentes em indivíduos alcoolistas. Como a saliva tem propriedades protetoras, a redução do fluxo torna a boca mais suscetível a injúrias, como as relacionadas à cárie e à periodontite. Podem ser observadas alterações morfológicas, como acúmulo de tecido adiposo, hiperplasia dos ductos e redução da proporção de células acinares. O consumo de etanol é responsável ainda pela redução dos níveis de imunoglobulinas presentes na saliva. A degradação do etanol gera metabólitos tóxicos, como o acetaldeído, que podem modificar a função das glândulas salivares. Existe a possibilidade de a saliva redistribuir o acetaldeído na boca, potencializando o dano produzido pelo consumo de etanol. Além disso, outros mecanismos podem estar presentes, como redução das prostaglandinas, desnutrição, alterações do sistema imune e estresse oxidativo, este último envolvido na patogênese de uma série de doenças crônico-degenerativas, entre elas o câncer. Conclusões: Os pacientes alcoolistas devem receber uma atenção especial em relação aos cuidados bucais, pois suas condições locais e sistêmicas os tornam mais suscetíveis a doenças da boca, como cárie, periodontite e câncer. DESCRITORES: GLÂNDULAS SALIVARES/patologia; ETANOL; TRANSTORNOS RELACIONADOS AO USO DE ÁLCOOL; MANIFESTAÇÕES BUCAIS; METANÁLISE.Editora da PUCRS - ediPUCRS2008-01-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRevisão de Literaturaapplication/pdfapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/1646Scientia Medica; Vol. 17 No. 2 (2007); 93-96Scientia Medica; v. 17 n. 2 (2007); 93-961980-61081806-5562reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSporenghttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/1646/1903https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1646/7884Carrard, Vinicius CoelhoMendez, MarinaNolde, JosuéAlves, Luciana DuarteFossati, Anna Christina MedeirosSant'Ana Filho, Manoelinfo:eu-repo/semantics/openAccess2013-07-17T13:30:50Zoai:ojs.revistaseletronicas.pucrs.br:article/1646Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2013-07-17T13:30:50Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.none.fl_str_mv Influence of ethanol consumption in salivary glands [Abstract in English]
Influência do Consumo de Etanol nas Glândulas Salivares
title Influence of ethanol consumption in salivary glands [Abstract in English]
spellingShingle Influence of ethanol consumption in salivary glands [Abstract in English]
Carrard, Vinicius Coelho
Glândula Salivar
Etanol
Boca
title_short Influence of ethanol consumption in salivary glands [Abstract in English]
title_full Influence of ethanol consumption in salivary glands [Abstract in English]
title_fullStr Influence of ethanol consumption in salivary glands [Abstract in English]
title_full_unstemmed Influence of ethanol consumption in salivary glands [Abstract in English]
title_sort Influence of ethanol consumption in salivary glands [Abstract in English]
author Carrard, Vinicius Coelho
author_facet Carrard, Vinicius Coelho
Mendez, Marina
Nolde, Josué
Alves, Luciana Duarte
Fossati, Anna Christina Medeiros
Sant'Ana Filho, Manoel
author_role author
author2 Mendez, Marina
Nolde, Josué
Alves, Luciana Duarte
Fossati, Anna Christina Medeiros
Sant'Ana Filho, Manoel
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Carrard, Vinicius Coelho
Mendez, Marina
Nolde, Josué
Alves, Luciana Duarte
Fossati, Anna Christina Medeiros
Sant'Ana Filho, Manoel
dc.subject.por.fl_str_mv Glândula Salivar
Etanol
Boca
topic Glândula Salivar
Etanol
Boca
description Aims: To perform a literature review about alcohol effects on salivary gland. Source of data: Articles were retrieved from Medline data base using the key-words alcohol/ethanol and salivary glands. Summary of findings: Increase in ethanol consumption has been observed in people, and it causes alterations in several systems. Enlargement of salivary glands and salivary flow decrease have been observed in alcoholics. The decreased salivary flow results in increased susceptibility of injuries to the mouth, like those related to caries and periodontitis, because saliva has protective properties. Morphology alterations like adipocytes infiltration, ductal hyperplasia and decrease in acinar cells ratio can be observed. The ethanol consumption reduces salivary flow, and immunoglobulins and antioxidants levels decrease in saliva. Ethanol degradation generates toxic metabolites, like acetaldehyde, that can modify the salivary gland function. There is a possibility that saliva helps on acetaldehyde distribution in the mouth, improving ethanol consumption damage. In addition, other mechanisms are included in this damage like decrease in prostaglandins, malnutrition, immune system alterations and oxidative stress. Oxidative stress may be involved in pathogenesis of several chronicdegenerative diseases, like cancer. Conclusions: The alcoholics must receive a special attention in oral care because its local and systemic conditions improve susceptibility to oral illnesses, such as caries, periodontitis and cancer. KEY WORDS: SALIVARY GLAND/pathology; ETHANOL; ALCOHOL-RELATED DISORDERS ; MOUTH DISEASES; METAANALYSIS.
publishDate 2008
dc.date.none.fl_str_mv 2008-01-08
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Revisão de Literatura
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1646
url https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1646
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1646/1903
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1646/7884
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
dc.source.none.fl_str_mv Scientia Medica; Vol. 17 No. 2 (2007); 93-96
Scientia Medica; v. 17 n. 2 (2007); 93-96
1980-6108
1806-5562
reponame:Scientia Medica (Porto Alegre. Online)
instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
instname_str Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron_str PUC_RS
institution PUC_RS
reponame_str Scientia Medica (Porto Alegre. Online)
collection Scientia Medica (Porto Alegre. Online)
repository.name.fl_str_mv Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
repository.mail.fl_str_mv scientiamedica@pucrs.br || editora.periodicos@pucrs.br
_version_ 1809101748483129344

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