Sociodemographic characteristics and clinical features of patients with adult polycystic kidney disease undergoing hemodialysis
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Scientia Medica (Porto Alegre. Online) |
Texto Completo: | https://revistaseletronicas.pucrs.br/scientiamedica/article/view/13358 |
Resumo: | AIMS: To analyze the socio-demographic and clinical characteristics of patients with adult polycystic kidney disease admitted to hemodialysis services in Northwestern Paraná state, Brazil. METHODS: This was an observational, descriptive and retrospective longitudinal study. Medical records of patients with polycystic kidneys who initiated hemodialysis between 1995 and 2012, in four centers that treat patients of the coverage area of the 15th Regional Health Region of Paraná state where analyzed. RESULTS: We found that 10.3% of hemodialysis patients had polycystic kidney disease as a leading cause of stage 5 of chronic kidney disease. The mean age of patients was 54.9±9.4 years (ranging between 27 and 74 years), with equal gender distribution and Caucasian predominance (72.9%). The average age of dialysis initiation was 50±10.2 years. The most common comorbidity was systemic hypertension (66.7%). Liver cyst was the main extra-renal manifestation (10.4%). Twenty-five percent of the patients required renal transplantation, and (22.9%) undergone nephrectomy. The most widely used classes of antihypertensive drugs were β-blockers (41.7%) and drugs that act on the renin-angiotensin system (31.3%), while 56.3% of patients were treated with recombinant human erythropoietin. CONCLUSIONS: This is a pioneering epidemiological study in Northwestern Paraná state. We found in this population a sociodemographic and clinical profile of adult polycystic kidney disease similar to that of North America and Europe, probably because the ethnic constitution of the sample was predominantly of Euro-descendants. |
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Sociodemographic characteristics and clinical features of patients with adult polycystic kidney disease undergoing hemodialysisCaracterísticas sociodemográficas e aspectos clínicos de pacientes com doença renal policística do adulto submetidos à hemodiálisePOLYCYSTIC KIDNEYAUTOSOMAL DOMINANT/epidemiologyPOLYCYSTIC KIDNEY DISEASESKIDNEY FAILURECHRONICEND-STAGE RENAL DISEASEHEMODIALYSISRIM POLICÍSTICO AUTOSSÔMICO DOMINANTE/epidemiologiaINSUFICIÊNCIA RENAL CRÔNICADOENÇA RENAL TERMINALDIÁLISE RENALHEMODIÁLISE.AIMS: To analyze the socio-demographic and clinical characteristics of patients with adult polycystic kidney disease admitted to hemodialysis services in Northwestern Paraná state, Brazil. METHODS: This was an observational, descriptive and retrospective longitudinal study. Medical records of patients with polycystic kidneys who initiated hemodialysis between 1995 and 2012, in four centers that treat patients of the coverage area of the 15th Regional Health Region of Paraná state where analyzed. RESULTS: We found that 10.3% of hemodialysis patients had polycystic kidney disease as a leading cause of stage 5 of chronic kidney disease. The mean age of patients was 54.9±9.4 years (ranging between 27 and 74 years), with equal gender distribution and Caucasian predominance (72.9%). The average age of dialysis initiation was 50±10.2 years. The most common comorbidity was systemic hypertension (66.7%). Liver cyst was the main extra-renal manifestation (10.4%). Twenty-five percent of the patients required renal transplantation, and (22.9%) undergone nephrectomy. The most widely used classes of antihypertensive drugs were β-blockers (41.7%) and drugs that act on the renin-angiotensin system (31.3%), while 56.3% of patients were treated with recombinant human erythropoietin. CONCLUSIONS: This is a pioneering epidemiological study in Northwestern Paraná state. We found in this population a sociodemographic and clinical profile of adult polycystic kidney disease similar to that of North America and Europe, probably because the ethnic constitution of the sample was predominantly of Euro-descendants.OBJETIVOS: Analisar as características sociodemográficas e clínicas de pacientes portadores da doença renal policística do adulto admitidos nos serviços de hemodiálise no noroeste do estado do Paraná. MÉTODOS: Trata-se de um estudo observacional, descritivo e retrospectivo. Foram revisados os prontuários de pacientes com rins policísticos admitidos para hemodiálise entre 1995 e 2012, em quatro centros que atendem pacientes da área de abrangência da 15ª Regional de Saúde do Paraná. RESULTADOS: Observou-se que 10,3% dos pacientes em hemodiálise tinham rins policísticos como principal causa de doença renal crônica estágio 5. A idade média dos pacientes foi de 54,9±9,4 anos (variando entre 27 e 74 anos), com distribuição igual entre os sexos e predominância caucasiana (72,9%). A idade média de ingresso na hemodiálise foi de 50±10,2 anos. A manifestação clínica associada mais comum foi a hipertensão arterial sistêmica (66,7%). Cisto hepático foi a principal manifestação extrarrenal (10,4%). Vinte e cinco por cento dos pacientes evoluíram para transplante renal e 22,9% foram submetidos à nefrectomia. As classes de drogas anti-hipertensivas mais amplamente usadas foram os β-bloqueadores (41,7%) e as drogas que diminuem a atividade do sistema renina-angiotensina (31,3%), enquanto 56,3% dos pacientes fizeram uso de eritropoetina humana recombinante. CONCLUSÕES: Este estudo epidemiológico foi pioneiro na região noroeste do Paraná. Encontrou-se, na população estudada, um perfil sociodemográfico e clínico da doença renal policística do adulto semelhante ao da América do Norte e Europa, provavelmente pela constituição étnica da amostragem ser predominantemente de euro-descendentes.Editora da PUCRS - ediPUCRS2013-10-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/13358Scientia Medica; Vol. 23 No. 3 (2013); 156-162Scientia Medica; v. 23 n. 3 (2013); 156-1621980-61081806-5562reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSporenghttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/13358/10206https://revistaseletronicas.pucrs.br/scientiamedica/article/view/13358/10207Alves, Everton FernandoTsuneto, Luiza TamieBorelli, Sueli DonizeteCadidé, Renata Camposde Freitas, Rosane AlmeidaFrança Gravena, Ângela AndréiaPelloso, Sandra Marisade Barros Carvalho, Maria Dalvainfo:eu-repo/semantics/openAccess2014-09-23T18:53:49Zoai:ojs.revistaseletronicas.pucrs.br:article/13358Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2014-09-23T18:53:49Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false |
dc.title.none.fl_str_mv |
Sociodemographic characteristics and clinical features of patients with adult polycystic kidney disease undergoing hemodialysis Características sociodemográficas e aspectos clínicos de pacientes com doença renal policística do adulto submetidos à hemodiálise |
title |
Sociodemographic characteristics and clinical features of patients with adult polycystic kidney disease undergoing hemodialysis |
spellingShingle |
Sociodemographic characteristics and clinical features of patients with adult polycystic kidney disease undergoing hemodialysis Alves, Everton Fernando POLYCYSTIC KIDNEY AUTOSOMAL DOMINANT/epidemiology POLYCYSTIC KIDNEY DISEASES KIDNEY FAILURE CHRONIC END-STAGE RENAL DISEASE HEMODIALYSIS RIM POLICÍSTICO AUTOSSÔMICO DOMINANTE/epidemiologia INSUFICIÊNCIA RENAL CRÔNICA DOENÇA RENAL TERMINAL DIÁLISE RENAL HEMODIÁLISE. |
title_short |
Sociodemographic characteristics and clinical features of patients with adult polycystic kidney disease undergoing hemodialysis |
title_full |
Sociodemographic characteristics and clinical features of patients with adult polycystic kidney disease undergoing hemodialysis |
title_fullStr |
Sociodemographic characteristics and clinical features of patients with adult polycystic kidney disease undergoing hemodialysis |
title_full_unstemmed |
Sociodemographic characteristics and clinical features of patients with adult polycystic kidney disease undergoing hemodialysis |
title_sort |
Sociodemographic characteristics and clinical features of patients with adult polycystic kidney disease undergoing hemodialysis |
author |
Alves, Everton Fernando |
author_facet |
Alves, Everton Fernando Tsuneto, Luiza Tamie Borelli, Sueli Donizete Cadidé, Renata Campos de Freitas, Rosane Almeida França Gravena, Ângela Andréia Pelloso, Sandra Marisa de Barros Carvalho, Maria Dalva |
author_role |
author |
author2 |
Tsuneto, Luiza Tamie Borelli, Sueli Donizete Cadidé, Renata Campos de Freitas, Rosane Almeida França Gravena, Ângela Andréia Pelloso, Sandra Marisa de Barros Carvalho, Maria Dalva |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Alves, Everton Fernando Tsuneto, Luiza Tamie Borelli, Sueli Donizete Cadidé, Renata Campos de Freitas, Rosane Almeida França Gravena, Ângela Andréia Pelloso, Sandra Marisa de Barros Carvalho, Maria Dalva |
dc.subject.por.fl_str_mv |
POLYCYSTIC KIDNEY AUTOSOMAL DOMINANT/epidemiology POLYCYSTIC KIDNEY DISEASES KIDNEY FAILURE CHRONIC END-STAGE RENAL DISEASE HEMODIALYSIS RIM POLICÍSTICO AUTOSSÔMICO DOMINANTE/epidemiologia INSUFICIÊNCIA RENAL CRÔNICA DOENÇA RENAL TERMINAL DIÁLISE RENAL HEMODIÁLISE. |
topic |
POLYCYSTIC KIDNEY AUTOSOMAL DOMINANT/epidemiology POLYCYSTIC KIDNEY DISEASES KIDNEY FAILURE CHRONIC END-STAGE RENAL DISEASE HEMODIALYSIS RIM POLICÍSTICO AUTOSSÔMICO DOMINANTE/epidemiologia INSUFICIÊNCIA RENAL CRÔNICA DOENÇA RENAL TERMINAL DIÁLISE RENAL HEMODIÁLISE. |
description |
AIMS: To analyze the socio-demographic and clinical characteristics of patients with adult polycystic kidney disease admitted to hemodialysis services in Northwestern Paraná state, Brazil. METHODS: This was an observational, descriptive and retrospective longitudinal study. Medical records of patients with polycystic kidneys who initiated hemodialysis between 1995 and 2012, in four centers that treat patients of the coverage area of the 15th Regional Health Region of Paraná state where analyzed. RESULTS: We found that 10.3% of hemodialysis patients had polycystic kidney disease as a leading cause of stage 5 of chronic kidney disease. The mean age of patients was 54.9±9.4 years (ranging between 27 and 74 years), with equal gender distribution and Caucasian predominance (72.9%). The average age of dialysis initiation was 50±10.2 years. The most common comorbidity was systemic hypertension (66.7%). Liver cyst was the main extra-renal manifestation (10.4%). Twenty-five percent of the patients required renal transplantation, and (22.9%) undergone nephrectomy. The most widely used classes of antihypertensive drugs were β-blockers (41.7%) and drugs that act on the renin-angiotensin system (31.3%), while 56.3% of patients were treated with recombinant human erythropoietin. CONCLUSIONS: This is a pioneering epidemiological study in Northwestern Paraná state. We found in this population a sociodemographic and clinical profile of adult polycystic kidney disease similar to that of North America and Europe, probably because the ethnic constitution of the sample was predominantly of Euro-descendants. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-10-19 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/13358 |
url |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/13358 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/13358/10206 https://revistaseletronicas.pucrs.br/scientiamedica/article/view/13358/10207 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Editora da PUCRS - ediPUCRS |
publisher.none.fl_str_mv |
Editora da PUCRS - ediPUCRS |
dc.source.none.fl_str_mv |
Scientia Medica; Vol. 23 No. 3 (2013); 156-162 Scientia Medica; v. 23 n. 3 (2013); 156-162 1980-6108 1806-5562 reponame:Scientia Medica (Porto Alegre. Online) instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) instacron:PUC_RS |
instname_str |
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
instacron_str |
PUC_RS |
institution |
PUC_RS |
reponame_str |
Scientia Medica (Porto Alegre. Online) |
collection |
Scientia Medica (Porto Alegre. Online) |
repository.name.fl_str_mv |
Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
repository.mail.fl_str_mv |
scientiamedica@pucrs.br || editora.periodicos@pucrs.br |
_version_ |
1809101750085353472 |