Cost-effectiveness and cost-utility of hypertension and hyperlipidemia collaborative management between pharmacies and primary care in portugal alongside a trial compared with usual care (USFarmácia®)

Detalhes bibliográficos
Autor(a) principal: Costa, Suzete
Data de Publicação: 2022
Outros Autores: Guerreiro, José, Teixeira, Inês, Helling, Dennis K., Pereira, João, Mateus, Céu
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/144662
Resumo: Funding Information: The trial was promoted by the NHS Group of Primary Care Units [Agrupamento dos Centros de Saúde, or ACeS] of Baixo Mondego Region and the Portuguese National Association of Pharmacies [Associação Nacional das Farmácias, or ANF] and was funded by ANF. Study promoters and funders had no role in the design and conduct of the trial/study; collection, management, analysis, and interpretation of data; and writing, review, approval, or decision to submit this manuscript for publication. SC paid for the open access publication fee for this manuscript. Publisher Copyright: Copyright © 2022 Costa, Guerreiro, Teixeira, Helling, Pereira and Mateus.
id RCAP_06afc95b398640f334a67489a36dddca
oai_identifier_str oai:run.unl.pt:10362/144662
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Cost-effectiveness and cost-utility of hypertension and hyperlipidemia collaborative management between pharmacies and primary care in portugal alongside a trial compared with usual care (USFarmácia®)community pharmacycost-effectivenesscost-utilityeconomichyperlipidemiahypertensionprimary carereal-worldPharmacologyPharmacology (medical)SDG 3 - Good Health and Well-beingFunding Information: The trial was promoted by the NHS Group of Primary Care Units [Agrupamento dos Centros de Saúde, or ACeS] of Baixo Mondego Region and the Portuguese National Association of Pharmacies [Associação Nacional das Farmácias, or ANF] and was funded by ANF. Study promoters and funders had no role in the design and conduct of the trial/study; collection, management, analysis, and interpretation of data; and writing, review, approval, or decision to submit this manuscript for publication. SC paid for the open access publication fee for this manuscript. Publisher Copyright: Copyright © 2022 Costa, Guerreiro, Teixeira, Helling, Pereira and Mateus.Background: There is little experience in the economic evaluation of pharmacy/primary care collaborative health interventions using interprofessional technology-driven communication under real-world conditions. This study aimed to conduct cost-effectiveness and cost-utility analyses of a collaborative care intervention in hypertension and hyperlipidemia management between pharmacies and primary care versus usual (fragmented) care alongside a trial. Methods: An economic evaluation was conducted alongside a 6-month pragmatic quasi-experimental controlled trial. Data sources included primary care clinical software; pharmacy dispensing software; patient telephone surveys; and published literature. The target population was adult patients on hypertension and/or lipid-lowering medication. The perspective was societal. We collected patient-level data on resource use to estimate trial costs. Effect outcomes included blood pressure (BP) and quality-adjusted life years (QALYs). Bootstrapping was used to estimate uncertainty around the incremental cost-effectiveness and cost-utility ratios. Cost-effectiveness planes and acceptability curves were estimated. Results: The intervention was not shown to have reasonable levels of cost-effectiveness or cost-utility when compared to usual care as denoted by the levels of uncertainty expressed in wide confidence intervals. The probability of the intervention being cost-effective is 28% at the threshold of €20,000 per QALY gained and 57% at the threshold of €500 per mmHg systolic BP decrease. Conclusion: Considering the limitations of the trial which affected effectiveness and economic outcomes, our results are not generalizable for community pharmacy and primary care in Portugal. This research offers, however, valuable lessons on methods and strategies that can be used in future economic evaluations of collaborative public health interventions with the potential for reimbursement. Clinical trial registration: https://www.isrctn.com/ISRCTN13410498, identifier ISRCTN13410498Escola Nacional de Saúde Pública (ENSP)Comprehensive Health Research Centre (CHRC) - Pólo ENSPCentro de Investigação em Saúde Pública (CISP/PHRC)RUNCosta, SuzeteGuerreiro, JoséTeixeira, InêsHelling, Dennis K.Pereira, JoãoMateus, Céu2022-10-12T22:18:14Z2022-09-082022-09-08T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/144662eng1663-9812PURE: 47066861https://doi.org/10.3389/fphar.2022.903270info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:24:25Zoai:run.unl.pt:10362/144662Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:51:40.878233Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Cost-effectiveness and cost-utility of hypertension and hyperlipidemia collaborative management between pharmacies and primary care in portugal alongside a trial compared with usual care (USFarmácia®)
title Cost-effectiveness and cost-utility of hypertension and hyperlipidemia collaborative management between pharmacies and primary care in portugal alongside a trial compared with usual care (USFarmácia®)
spellingShingle Cost-effectiveness and cost-utility of hypertension and hyperlipidemia collaborative management between pharmacies and primary care in portugal alongside a trial compared with usual care (USFarmácia®)
Costa, Suzete
community pharmacy
cost-effectiveness
cost-utility
economic
hyperlipidemia
hypertension
primary care
real-world
Pharmacology
Pharmacology (medical)
SDG 3 - Good Health and Well-being
title_short Cost-effectiveness and cost-utility of hypertension and hyperlipidemia collaborative management between pharmacies and primary care in portugal alongside a trial compared with usual care (USFarmácia®)
title_full Cost-effectiveness and cost-utility of hypertension and hyperlipidemia collaborative management between pharmacies and primary care in portugal alongside a trial compared with usual care (USFarmácia®)
title_fullStr Cost-effectiveness and cost-utility of hypertension and hyperlipidemia collaborative management between pharmacies and primary care in portugal alongside a trial compared with usual care (USFarmácia®)
title_full_unstemmed Cost-effectiveness and cost-utility of hypertension and hyperlipidemia collaborative management between pharmacies and primary care in portugal alongside a trial compared with usual care (USFarmácia®)
title_sort Cost-effectiveness and cost-utility of hypertension and hyperlipidemia collaborative management between pharmacies and primary care in portugal alongside a trial compared with usual care (USFarmácia®)
author Costa, Suzete
author_facet Costa, Suzete
Guerreiro, José
Teixeira, Inês
Helling, Dennis K.
Pereira, João
Mateus, Céu
author_role author
author2 Guerreiro, José
Teixeira, Inês
Helling, Dennis K.
Pereira, João
Mateus, Céu
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Escola Nacional de Saúde Pública (ENSP)
Comprehensive Health Research Centre (CHRC) - Pólo ENSP
Centro de Investigação em Saúde Pública (CISP/PHRC)
RUN
dc.contributor.author.fl_str_mv Costa, Suzete
Guerreiro, José
Teixeira, Inês
Helling, Dennis K.
Pereira, João
Mateus, Céu
dc.subject.por.fl_str_mv community pharmacy
cost-effectiveness
cost-utility
economic
hyperlipidemia
hypertension
primary care
real-world
Pharmacology
Pharmacology (medical)
SDG 3 - Good Health and Well-being
topic community pharmacy
cost-effectiveness
cost-utility
economic
hyperlipidemia
hypertension
primary care
real-world
Pharmacology
Pharmacology (medical)
SDG 3 - Good Health and Well-being
description Funding Information: The trial was promoted by the NHS Group of Primary Care Units [Agrupamento dos Centros de Saúde, or ACeS] of Baixo Mondego Region and the Portuguese National Association of Pharmacies [Associação Nacional das Farmácias, or ANF] and was funded by ANF. Study promoters and funders had no role in the design and conduct of the trial/study; collection, management, analysis, and interpretation of data; and writing, review, approval, or decision to submit this manuscript for publication. SC paid for the open access publication fee for this manuscript. Publisher Copyright: Copyright © 2022 Costa, Guerreiro, Teixeira, Helling, Pereira and Mateus.
publishDate 2022
dc.date.none.fl_str_mv 2022-10-12T22:18:14Z
2022-09-08
2022-09-08T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/144662
url http://hdl.handle.net/10362/144662
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1663-9812
PURE: 47066861
https://doi.org/10.3389/fphar.2022.903270
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799138109832560640

Registros relacionados