To be or not to be a compatible solute: Bioversatility of mannosylglycerate and glucosylglycerate
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/3852 https://doi.org/10.1016/j.syapm.2008.05.002 |
Resumo: | Mannosylglycerate (MG) is an intracellular organic solute found in some red algae, and several thermophilic bacteria and hyperthermophilic archaea. Glucosylglycerate (GG) was identified at the reducing end of a polysaccharide from mycobacteria and in a free form in a very few mesophilic bacteria and halophilic archaea. MG has a genuine role in the osmoadaptation and possibly in thermal protection of many hyper/thermophilic bacteria and archaea, but its role in red algae, where it was identified long before hyperthermophiles were even known to exist, remains to be clarified. The GG-containing polysaccharide was initially detected in Mycobacterium phlei and found to regulate fatty acid synthesis. More recently, GG has been found to be a major compatible solute under salt stress and nitrogen starvation in a few microorganisms. This review summarizes the occurrence and physiology of MG accumulation, as well as the distribution of GG, as a free solute or associated with larger macromolecules. We also focus on the recently identified pathways for the synthesis of both molecules, which were elucidated by studying hyper/thermophilic MG-accumulating organisms. The blooming era of genomics has now allowed the detection of these genes in fungi and mosses, opening a research avenue that spans the three domains of life, into the role of these two sugar derivatives. |
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To be or not to be a compatible solute: Bioversatility of mannosylglycerate and glucosylglycerateCompatible solutesMannosylglycerateGlucosylglycerateBiosynthesisMannosylglycerate (MG) is an intracellular organic solute found in some red algae, and several thermophilic bacteria and hyperthermophilic archaea. Glucosylglycerate (GG) was identified at the reducing end of a polysaccharide from mycobacteria and in a free form in a very few mesophilic bacteria and halophilic archaea. MG has a genuine role in the osmoadaptation and possibly in thermal protection of many hyper/thermophilic bacteria and archaea, but its role in red algae, where it was identified long before hyperthermophiles were even known to exist, remains to be clarified. The GG-containing polysaccharide was initially detected in Mycobacterium phlei and found to regulate fatty acid synthesis. More recently, GG has been found to be a major compatible solute under salt stress and nitrogen starvation in a few microorganisms. This review summarizes the occurrence and physiology of MG accumulation, as well as the distribution of GG, as a free solute or associated with larger macromolecules. We also focus on the recently identified pathways for the synthesis of both molecules, which were elucidated by studying hyper/thermophilic MG-accumulating organisms. The blooming era of genomics has now allowed the detection of these genes in fungi and mosses, opening a research avenue that spans the three domains of life, into the role of these two sugar derivatives.http://www.sciencedirect.com/science/article/B7GVX-4SWP1Y0-1/1/21fa8b34b94c7aee64e8337e26bd247c2008info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleaplication/PDFhttp://hdl.handle.net/10316/3852http://hdl.handle.net/10316/3852https://doi.org/10.1016/j.syapm.2008.05.002engSystematic and Applied Microbiology. 31:3 (2008) 159-168Empadinhas, NunoCosta, Milton S. dainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2020-11-06T16:59:20Zoai:estudogeral.uc.pt:10316/3852Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:55:47.055449Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
To be or not to be a compatible solute: Bioversatility of mannosylglycerate and glucosylglycerate |
title |
To be or not to be a compatible solute: Bioversatility of mannosylglycerate and glucosylglycerate |
spellingShingle |
To be or not to be a compatible solute: Bioversatility of mannosylglycerate and glucosylglycerate Empadinhas, Nuno Compatible solutes Mannosylglycerate Glucosylglycerate Biosynthesis |
title_short |
To be or not to be a compatible solute: Bioversatility of mannosylglycerate and glucosylglycerate |
title_full |
To be or not to be a compatible solute: Bioversatility of mannosylglycerate and glucosylglycerate |
title_fullStr |
To be or not to be a compatible solute: Bioversatility of mannosylglycerate and glucosylglycerate |
title_full_unstemmed |
To be or not to be a compatible solute: Bioversatility of mannosylglycerate and glucosylglycerate |
title_sort |
To be or not to be a compatible solute: Bioversatility of mannosylglycerate and glucosylglycerate |
author |
Empadinhas, Nuno |
author_facet |
Empadinhas, Nuno Costa, Milton S. da |
author_role |
author |
author2 |
Costa, Milton S. da |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Empadinhas, Nuno Costa, Milton S. da |
dc.subject.por.fl_str_mv |
Compatible solutes Mannosylglycerate Glucosylglycerate Biosynthesis |
topic |
Compatible solutes Mannosylglycerate Glucosylglycerate Biosynthesis |
description |
Mannosylglycerate (MG) is an intracellular organic solute found in some red algae, and several thermophilic bacteria and hyperthermophilic archaea. Glucosylglycerate (GG) was identified at the reducing end of a polysaccharide from mycobacteria and in a free form in a very few mesophilic bacteria and halophilic archaea. MG has a genuine role in the osmoadaptation and possibly in thermal protection of many hyper/thermophilic bacteria and archaea, but its role in red algae, where it was identified long before hyperthermophiles were even known to exist, remains to be clarified. The GG-containing polysaccharide was initially detected in Mycobacterium phlei and found to regulate fatty acid synthesis. More recently, GG has been found to be a major compatible solute under salt stress and nitrogen starvation in a few microorganisms. This review summarizes the occurrence and physiology of MG accumulation, as well as the distribution of GG, as a free solute or associated with larger macromolecules. We also focus on the recently identified pathways for the synthesis of both molecules, which were elucidated by studying hyper/thermophilic MG-accumulating organisms. The blooming era of genomics has now allowed the detection of these genes in fungi and mosses, opening a research avenue that spans the three domains of life, into the role of these two sugar derivatives. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/3852 http://hdl.handle.net/10316/3852 https://doi.org/10.1016/j.syapm.2008.05.002 |
url |
http://hdl.handle.net/10316/3852 https://doi.org/10.1016/j.syapm.2008.05.002 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Systematic and Applied Microbiology. 31:3 (2008) 159-168 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
aplication/PDF |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133844228538368 |