Extraction and Analysis of Compounds with Antibacterial Potential from the Red Alga Grateloupia turuturu
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/101594 https://doi.org/10.3390/jmse7070220 |
Resumo: | Nowadays, the development of new drugs only relies on a small number of molecules and 50% of all existent drugs are extracted or synthetically obtained. This work intends to evaluate the antibacterial potential of the ethanolic and polysaccharide extracts obtained from Grateloupia turuturu and to characterize the composition of the alga’s polysaccharides by FTIR-ATR. We used sequential extraction to obtain the extracts that were tested against S. aureus and E. coli. The ethanolic extracts in E. coli, at the highest concentration used (15 mg mL1) showed 45.7% (Tetrasporophyte extract) and 55.1% (Carposporophyte extract) of growth reduction and in S. aureus 56.2% (T extract) and 51.8% (C extract). Polysaccharide extracts started showing significant reduction e ect on E. coli and S. aureus growth at 7.5 mg mL1 with a reduction of 54.9% and 39.5%, respectively. At 15 mg mL1 the reduction observed was 88.5% and 85.4%. The FTIR-ATR allowed to characterize G. turuturu’s polysaccharides concluding that it is composed by a hybrid kappa/iota carrageenan with traces of agar, in both phases of the life cycle. This work allows us to conclude about the antibacterial properties of this alga and the compounds that might be behind this activity, showing that there’s a lot more than a small number of molecules that can be used as natural drugs. |
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Extraction and Analysis of Compounds with Antibacterial Potential from the Red Alga Grateloupia turuturuGrateloupia turuturuethanolic extractspolysaccharides extractantibacterial propertieshybrid phycocolloidpolysaccharides characterizationNowadays, the development of new drugs only relies on a small number of molecules and 50% of all existent drugs are extracted or synthetically obtained. This work intends to evaluate the antibacterial potential of the ethanolic and polysaccharide extracts obtained from Grateloupia turuturu and to characterize the composition of the alga’s polysaccharides by FTIR-ATR. We used sequential extraction to obtain the extracts that were tested against S. aureus and E. coli. The ethanolic extracts in E. coli, at the highest concentration used (15 mg mL1) showed 45.7% (Tetrasporophyte extract) and 55.1% (Carposporophyte extract) of growth reduction and in S. aureus 56.2% (T extract) and 51.8% (C extract). Polysaccharide extracts started showing significant reduction e ect on E. coli and S. aureus growth at 7.5 mg mL1 with a reduction of 54.9% and 39.5%, respectively. At 15 mg mL1 the reduction observed was 88.5% and 85.4%. The FTIR-ATR allowed to characterize G. turuturu’s polysaccharides concluding that it is composed by a hybrid kappa/iota carrageenan with traces of agar, in both phases of the life cycle. This work allows us to conclude about the antibacterial properties of this alga and the compounds that might be behind this activity, showing that there’s a lot more than a small number of molecules that can be used as natural drugs.2019info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/101594http://hdl.handle.net/10316/101594https://doi.org/10.3390/jmse7070220eng2077-1312Cardoso, IsabelCotas, JoãoRodrigues, AnaFerreira, DanielOsório, NádiaPereira, Leonelinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-07T13:42:01Zoai:estudogeral.uc.pt:10316/101594Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:18:45.220534Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Extraction and Analysis of Compounds with Antibacterial Potential from the Red Alga Grateloupia turuturu |
title |
Extraction and Analysis of Compounds with Antibacterial Potential from the Red Alga Grateloupia turuturu |
spellingShingle |
Extraction and Analysis of Compounds with Antibacterial Potential from the Red Alga Grateloupia turuturu Cardoso, Isabel Grateloupia turuturu ethanolic extracts polysaccharides extract antibacterial properties hybrid phycocolloid polysaccharides characterization |
title_short |
Extraction and Analysis of Compounds with Antibacterial Potential from the Red Alga Grateloupia turuturu |
title_full |
Extraction and Analysis of Compounds with Antibacterial Potential from the Red Alga Grateloupia turuturu |
title_fullStr |
Extraction and Analysis of Compounds with Antibacterial Potential from the Red Alga Grateloupia turuturu |
title_full_unstemmed |
Extraction and Analysis of Compounds with Antibacterial Potential from the Red Alga Grateloupia turuturu |
title_sort |
Extraction and Analysis of Compounds with Antibacterial Potential from the Red Alga Grateloupia turuturu |
author |
Cardoso, Isabel |
author_facet |
Cardoso, Isabel Cotas, João Rodrigues, Ana Ferreira, Daniel Osório, Nádia Pereira, Leonel |
author_role |
author |
author2 |
Cotas, João Rodrigues, Ana Ferreira, Daniel Osório, Nádia Pereira, Leonel |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Cardoso, Isabel Cotas, João Rodrigues, Ana Ferreira, Daniel Osório, Nádia Pereira, Leonel |
dc.subject.por.fl_str_mv |
Grateloupia turuturu ethanolic extracts polysaccharides extract antibacterial properties hybrid phycocolloid polysaccharides characterization |
topic |
Grateloupia turuturu ethanolic extracts polysaccharides extract antibacterial properties hybrid phycocolloid polysaccharides characterization |
description |
Nowadays, the development of new drugs only relies on a small number of molecules and 50% of all existent drugs are extracted or synthetically obtained. This work intends to evaluate the antibacterial potential of the ethanolic and polysaccharide extracts obtained from Grateloupia turuturu and to characterize the composition of the alga’s polysaccharides by FTIR-ATR. We used sequential extraction to obtain the extracts that were tested against S. aureus and E. coli. The ethanolic extracts in E. coli, at the highest concentration used (15 mg mL1) showed 45.7% (Tetrasporophyte extract) and 55.1% (Carposporophyte extract) of growth reduction and in S. aureus 56.2% (T extract) and 51.8% (C extract). Polysaccharide extracts started showing significant reduction e ect on E. coli and S. aureus growth at 7.5 mg mL1 with a reduction of 54.9% and 39.5%, respectively. At 15 mg mL1 the reduction observed was 88.5% and 85.4%. The FTIR-ATR allowed to characterize G. turuturu’s polysaccharides concluding that it is composed by a hybrid kappa/iota carrageenan with traces of agar, in both phases of the life cycle. This work allows us to conclude about the antibacterial properties of this alga and the compounds that might be behind this activity, showing that there’s a lot more than a small number of molecules that can be used as natural drugs. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/101594 http://hdl.handle.net/10316/101594 https://doi.org/10.3390/jmse7070220 |
url |
http://hdl.handle.net/10316/101594 https://doi.org/10.3390/jmse7070220 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2077-1312 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799134082201812992 |