Foveal Avascular Zone Area Quantification with OCT Angiography Following Successful Rhegmatogenous Retinal Detachment Repair
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.48560/rspo.25889 |
Resumo: | INTRODUCTION: Visual prognosis after a rhegmatogenous retinal detachment (RRD) may relate to the vascular status of the macula. Recent works have demonstrated that optical coherence tomography angiography (OCTA) can reproducibly evaluate foveal avascular zone (FAZ) dimensions. The aim of this research was to study the FAZ area at the superficial and deep capillary plexus using OCTA after successful RRD repair and correlate this data with postoperative visual recovery. METHODS: This was a prospective case-control study that included all patients diagnosed between January and March of 2021 with an RRD that was successfully repaired with a single, uncomplicated surgical procedure (pars plana vitrectomy with gas tamponade). Two groups were created according to macula involvement (macula-on and macula-off) and control data was obtained from the fellow healthy eye. FAZ areas were independently measured by manually outlining the inner border of foveal capillaries of superficial (SCP) and deep capillary plexus (DCP) using OCTA system software. RESULTS: We included 12 eyes (6 macula-on and 6 macula-off) and 12 controls (12 patients). All eyes with RRD had significantly larger FAZ areas of both SCP (study group: 0.30 ± 0.09 mm2; control group: 0.26 ± 0.09 mm2; p<0.001) and DCP (study group: 0.37 ± 0.06 mm2; control group: 0.33 ± 0.05 mm2; p=0.002). In the macula-off group this difference was greater than in the macula-on group for both superficial (macula-off group=+0.051 mm2; macula-on group=+0.027 mm2; p=0.027) and deep (macula off group=+0.062 mm2, macula-on group=+0,023 mm2 , p=0.062) FAZ areas. Postoperative best corrected visual acuity was significantly higher in the macula-on group (macula-on group=0.81; macula-off group=0.55; p=0.029). CONCLUSION: FAZ area enlargement observed after a retinal detachment demonstrates that the latter may lead to an ischemic injury. When the macula is involved this damage may be greater which could explain a larger FAZ area. Slighter changes in FAZ area in macula-on RRDs may explain a better visual prognosis associated with this type of detachment. |
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Foveal Avascular Zone Area Quantification with OCT Angiography Following Successful Rhegmatogenous Retinal Detachment RepairQuantificação da Área da Zona Avascular Foveal com OCTA Após Reparação Bem Sucedida de Descolamento de Retina RegmatogéneoArtigos OriginaisINTRODUCTION: Visual prognosis after a rhegmatogenous retinal detachment (RRD) may relate to the vascular status of the macula. Recent works have demonstrated that optical coherence tomography angiography (OCTA) can reproducibly evaluate foveal avascular zone (FAZ) dimensions. The aim of this research was to study the FAZ area at the superficial and deep capillary plexus using OCTA after successful RRD repair and correlate this data with postoperative visual recovery. METHODS: This was a prospective case-control study that included all patients diagnosed between January and March of 2021 with an RRD that was successfully repaired with a single, uncomplicated surgical procedure (pars plana vitrectomy with gas tamponade). Two groups were created according to macula involvement (macula-on and macula-off) and control data was obtained from the fellow healthy eye. FAZ areas were independently measured by manually outlining the inner border of foveal capillaries of superficial (SCP) and deep capillary plexus (DCP) using OCTA system software. RESULTS: We included 12 eyes (6 macula-on and 6 macula-off) and 12 controls (12 patients). All eyes with RRD had significantly larger FAZ areas of both SCP (study group: 0.30 ± 0.09 mm2; control group: 0.26 ± 0.09 mm2; p<0.001) and DCP (study group: 0.37 ± 0.06 mm2; control group: 0.33 ± 0.05 mm2; p=0.002). In the macula-off group this difference was greater than in the macula-on group for both superficial (macula-off group=+0.051 mm2; macula-on group=+0.027 mm2; p=0.027) and deep (macula off group=+0.062 mm2, macula-on group=+0,023 mm2 , p=0.062) FAZ areas. Postoperative best corrected visual acuity was significantly higher in the macula-on group (macula-on group=0.81; macula-off group=0.55; p=0.029). CONCLUSION: FAZ area enlargement observed after a retinal detachment demonstrates that the latter may lead to an ischemic injury. When the macula is involved this damage may be greater which could explain a larger FAZ area. Slighter changes in FAZ area in macula-on RRDs may explain a better visual prognosis associated with this type of detachment.INTRODUÇÃO: O prognóstico visual após descolamento de retina regmatogéneo (DRR) pode relacionar-se com o estado vascular da mácula. Alguns trabalhos recentes demonstraram que a angiografia por tomografia de coerência óptica (OCTA) avalia de forma reprodutível as dimensões da zona avascular foveal (ZAF). O objetivo deste trabalho foi estudar a área da ZAF, através de OCTA, após cirurgia de DRR e correlacioná-la com a recuperação visual pós-operatória. MÉTODOS: Este foi um estudo prospetivo, caso-controlo, que incluiu todos os doentes diagnosticados entre Janeiro e Março de 2021 com um DRR tratado com vitrectomia via pars plana com tamponamento com gás. Criaram-se dois grupos de acordo com o envolvimento macular (mácula on e mácula off) e o olho adelfo saudável foi utilizado como controlo. As áreas da ZAF foram calculadas através de software do OCTA após delineação manual do bordo interno dos capilares foveais do plexo capilar superficial (PCS) e profundo (PCP). RESULTADOS E DISCUSSÃO: Foram incluídos 12 olhos (6 mácula on e 6 mácula off) e 12 controlos (12 doentes). Todos os olhos com DRR tinham áreas da ZAF significativamente maiores no PCS (grupo DRR: 0,30 ± 0,09 mm2; grupo controlo: 0,26 ± 0,09 mm2; p<0,001) e no PCP (grupo DRR: 0,37 ± 0,06 mm2; grupo controlo: 0,33 ± 0,05 mm2; p=0,002). No grupo mácula off esta diferença foi maior que no grupo mácula on para o plexo superficial (grupo mácula off =+0,051 mm2; grupo mácula on=+0,027 mm2; p=0,027) e também para o plexo profundo (grupo mácula off=+0,062 mm2, grupo mácula on=+0,023 mm2, p=0,062). A acuidade visual pós-operatória foi significativamente maior no grupo mácula on (grupo mácula on=0,81; grupo mácula off=0,55; p=0,029). CONCLUSÃO: O alargamento da área da ZAF após descolamento de retina demonstra que este pode causar dano isquémico. Quando a mácula está envolvida, esta lesão pode ser maior o que pode explicar uma área mais larga da ZAF. Um menor alargamento da área da ZAF em DRRs com mácula on pode explicar o melhor prognóstico visual associado a este tipo de descolamento.Ajnet2023-12-29info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.48560/rspo.25889eng1646-69501646-6950Portela, MarianaArede, PedroPicoto, MariaDonato, SofiaVaz, Fernandainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-04T20:30:28Zoai:ojs.revistas.rcaap.pt:article/25889Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:30:07.820149Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Foveal Avascular Zone Area Quantification with OCT Angiography Following Successful Rhegmatogenous Retinal Detachment Repair Quantificação da Área da Zona Avascular Foveal com OCTA Após Reparação Bem Sucedida de Descolamento de Retina Regmatogéneo |
title |
Foveal Avascular Zone Area Quantification with OCT Angiography Following Successful Rhegmatogenous Retinal Detachment Repair |
spellingShingle |
Foveal Avascular Zone Area Quantification with OCT Angiography Following Successful Rhegmatogenous Retinal Detachment Repair Portela, Mariana Artigos Originais |
title_short |
Foveal Avascular Zone Area Quantification with OCT Angiography Following Successful Rhegmatogenous Retinal Detachment Repair |
title_full |
Foveal Avascular Zone Area Quantification with OCT Angiography Following Successful Rhegmatogenous Retinal Detachment Repair |
title_fullStr |
Foveal Avascular Zone Area Quantification with OCT Angiography Following Successful Rhegmatogenous Retinal Detachment Repair |
title_full_unstemmed |
Foveal Avascular Zone Area Quantification with OCT Angiography Following Successful Rhegmatogenous Retinal Detachment Repair |
title_sort |
Foveal Avascular Zone Area Quantification with OCT Angiography Following Successful Rhegmatogenous Retinal Detachment Repair |
author |
Portela, Mariana |
author_facet |
Portela, Mariana Arede, Pedro Picoto, Maria Donato, Sofia Vaz, Fernanda |
author_role |
author |
author2 |
Arede, Pedro Picoto, Maria Donato, Sofia Vaz, Fernanda |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Portela, Mariana Arede, Pedro Picoto, Maria Donato, Sofia Vaz, Fernanda |
dc.subject.por.fl_str_mv |
Artigos Originais |
topic |
Artigos Originais |
description |
INTRODUCTION: Visual prognosis after a rhegmatogenous retinal detachment (RRD) may relate to the vascular status of the macula. Recent works have demonstrated that optical coherence tomography angiography (OCTA) can reproducibly evaluate foveal avascular zone (FAZ) dimensions. The aim of this research was to study the FAZ area at the superficial and deep capillary plexus using OCTA after successful RRD repair and correlate this data with postoperative visual recovery. METHODS: This was a prospective case-control study that included all patients diagnosed between January and March of 2021 with an RRD that was successfully repaired with a single, uncomplicated surgical procedure (pars plana vitrectomy with gas tamponade). Two groups were created according to macula involvement (macula-on and macula-off) and control data was obtained from the fellow healthy eye. FAZ areas were independently measured by manually outlining the inner border of foveal capillaries of superficial (SCP) and deep capillary plexus (DCP) using OCTA system software. RESULTS: We included 12 eyes (6 macula-on and 6 macula-off) and 12 controls (12 patients). All eyes with RRD had significantly larger FAZ areas of both SCP (study group: 0.30 ± 0.09 mm2; control group: 0.26 ± 0.09 mm2; p<0.001) and DCP (study group: 0.37 ± 0.06 mm2; control group: 0.33 ± 0.05 mm2; p=0.002). In the macula-off group this difference was greater than in the macula-on group for both superficial (macula-off group=+0.051 mm2; macula-on group=+0.027 mm2; p=0.027) and deep (macula off group=+0.062 mm2, macula-on group=+0,023 mm2 , p=0.062) FAZ areas. Postoperative best corrected visual acuity was significantly higher in the macula-on group (macula-on group=0.81; macula-off group=0.55; p=0.029). CONCLUSION: FAZ area enlargement observed after a retinal detachment demonstrates that the latter may lead to an ischemic injury. When the macula is involved this damage may be greater which could explain a larger FAZ area. Slighter changes in FAZ area in macula-on RRDs may explain a better visual prognosis associated with this type of detachment. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-12-29 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.48560/rspo.25889 |
url |
https://doi.org/10.48560/rspo.25889 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
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1646-6950 1646-6950 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Ajnet |
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Ajnet |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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