Evolution of the concepts of endometrosis, post breeding endometritis, and susceptibility of mares

Detalhes bibliográficos
Autor(a) principal: Katila, Terttu
Data de Publicação: 2022
Outros Autores: Ferreira-Dias, Graça
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.5/24266
Resumo: Research Areas: Agriculture ; Veterinary Sciences ; Zoology
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spelling Evolution of the concepts of endometrosis, post breeding endometritis, and susceptibility of maresMareBreedingEndometritisEndometrosisInflammationFibrosisNeutrophilsCytokinesResearch Areas: Agriculture ; Veterinary Sciences ; ZoologyIn this paper, the evolution of our understanding about post breeding endometritis (PBE), the susceptibility of mares, and events leading to endometrosis are reviewed. When sperm arrive in the uterus, pro-inflammatory cytokines and chemokines are released. They attract neutrophils and induce modulatory cytokines which control inflammation. In susceptible mares, this physiological defense can be prolonged since the pattern of cytokine release differs from that of resistant mares being delayed and weaker for anti-inflammatory cytokines. Delayed uterine clearance due to conformational defects, deficient myometrial contractions, and failure of the cervix to relax is detected by intrauterine fluid accumulation and is an important reason for susceptibility to endometritis. Multiparous aged mares are more likely to be susceptible. Untreated prolonged PBE can lead to bacterial or fungal endometritis called persistent or chronic endometritis. Exuberant or prolonged neutrophilia and cytokine release can have deleterious and permanent effects in inducing endometrosis. Interactions of neutrophils, cytokines, and prostaglandins in the formation of collagen and extracellular matrix in the pathogenesis of fibrosis are discussed. Endometritis and endometrosis are interconnected, influencing each other. It is suggested that they represent epigenetic changes induced by age and hostile uterine environmentMDPIRepositório da Universidade de LisboaKatila, TerttuFerreira-Dias, Graça2022-05-09T22:51:11Z2022-03-192022-03-19T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.5/24266engKatila T, Ferreira-Dias G. 2022. Evolution of the concepts of endometrosis, post breeding endometritis, and susceptibility of mares. Animals, 12(6):779. Doi 10.3390/ani120607792076-261510.3390/ani12060779info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-06T14:53:55Zoai:www.repository.utl.pt:10400.5/24266Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:08:21.459799Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Evolution of the concepts of endometrosis, post breeding endometritis, and susceptibility of mares
title Evolution of the concepts of endometrosis, post breeding endometritis, and susceptibility of mares
spellingShingle Evolution of the concepts of endometrosis, post breeding endometritis, and susceptibility of mares
Katila, Terttu
Mare
Breeding
Endometritis
Endometrosis
Inflammation
Fibrosis
Neutrophils
Cytokines
title_short Evolution of the concepts of endometrosis, post breeding endometritis, and susceptibility of mares
title_full Evolution of the concepts of endometrosis, post breeding endometritis, and susceptibility of mares
title_fullStr Evolution of the concepts of endometrosis, post breeding endometritis, and susceptibility of mares
title_full_unstemmed Evolution of the concepts of endometrosis, post breeding endometritis, and susceptibility of mares
title_sort Evolution of the concepts of endometrosis, post breeding endometritis, and susceptibility of mares
author Katila, Terttu
author_facet Katila, Terttu
Ferreira-Dias, Graça
author_role author
author2 Ferreira-Dias, Graça
author2_role author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Katila, Terttu
Ferreira-Dias, Graça
dc.subject.por.fl_str_mv Mare
Breeding
Endometritis
Endometrosis
Inflammation
Fibrosis
Neutrophils
Cytokines
topic Mare
Breeding
Endometritis
Endometrosis
Inflammation
Fibrosis
Neutrophils
Cytokines
description Research Areas: Agriculture ; Veterinary Sciences ; Zoology
publishDate 2022
dc.date.none.fl_str_mv 2022-05-09T22:51:11Z
2022-03-19
2022-03-19T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.5/24266
url http://hdl.handle.net/10400.5/24266
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Katila T, Ferreira-Dias G. 2022. Evolution of the concepts of endometrosis, post breeding endometritis, and susceptibility of mares. Animals, 12(6):779. Doi 10.3390/ani12060779
2076-2615
10.3390/ani12060779
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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