Lipoprotein(a) as a novel therapeutic target for preventing cardiovascular disease : a whiter shade of pale?
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10451/44914 |
Resumo: | © 2019 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. This is an open access article under CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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Lipoprotein(a) as a novel therapeutic target for preventing cardiovascular disease : a whiter shade of pale?Lp(a) como um novo alvo terapêutico na prevenção da doença cardiovascular : uma luz ao fundo do túnel?Cardiovascular DiseasesLipoprotein(a)© 2019 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. This is an open access article under CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/)Research on the importance of lipoprotein(a) [Lp(a)] gained new momentum when it became a potential therapeutic target. Our understanding of this mysterious circulating lipoprotein particle has undergone advances and setbacks since its discovery in 1963 by Kåre Berg’s group.1 Lp(a) is composed of liver-derived apolipoprotein A and apolipoprotein B-100, and has a similar structure to both low-density lipoprotein cholesterol (LDL-C) and plasminogen. Lp(a) thus has a proatherogenic and a prothrombotic component, and is associated with the pathogenesis of cardiovascular disease (CVD).ElsevierRepositório da Universidade de LisboaFiuza, Manuela2020-11-17T16:49:57Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/44914engRev Port Cardiol. 2019 Jul;38(7):495-4960870-255110.1016/j.repc.2019.08.0062174-2030info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:46:16Zoai:repositorio.ul.pt:10451/44914Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:57:24.610126Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Lipoprotein(a) as a novel therapeutic target for preventing cardiovascular disease : a whiter shade of pale? Lp(a) como um novo alvo terapêutico na prevenção da doença cardiovascular : uma luz ao fundo do túnel? |
title |
Lipoprotein(a) as a novel therapeutic target for preventing cardiovascular disease : a whiter shade of pale? |
spellingShingle |
Lipoprotein(a) as a novel therapeutic target for preventing cardiovascular disease : a whiter shade of pale? Fiuza, Manuela Cardiovascular Diseases Lipoprotein(a) |
title_short |
Lipoprotein(a) as a novel therapeutic target for preventing cardiovascular disease : a whiter shade of pale? |
title_full |
Lipoprotein(a) as a novel therapeutic target for preventing cardiovascular disease : a whiter shade of pale? |
title_fullStr |
Lipoprotein(a) as a novel therapeutic target for preventing cardiovascular disease : a whiter shade of pale? |
title_full_unstemmed |
Lipoprotein(a) as a novel therapeutic target for preventing cardiovascular disease : a whiter shade of pale? |
title_sort |
Lipoprotein(a) as a novel therapeutic target for preventing cardiovascular disease : a whiter shade of pale? |
author |
Fiuza, Manuela |
author_facet |
Fiuza, Manuela |
author_role |
author |
dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
dc.contributor.author.fl_str_mv |
Fiuza, Manuela |
dc.subject.por.fl_str_mv |
Cardiovascular Diseases Lipoprotein(a) |
topic |
Cardiovascular Diseases Lipoprotein(a) |
description |
© 2019 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. This is an open access article under CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019 2019-01-01T00:00:00Z 2020-11-17T16:49:57Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10451/44914 |
url |
http://hdl.handle.net/10451/44914 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Rev Port Cardiol. 2019 Jul;38(7):495-496 0870-2551 10.1016/j.repc.2019.08.006 2174-2030 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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