Transient Symptomatic Zinc Deficiency in an Exclusively Breastfed Infant
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/4694 |
Resumo: | A 3-month-old, full term female infant, adequate for gestational age, and exclusively breastfed, was admitted with a 10 day history of generalised scaling erythematous dermatitis, affecting the face (perinasal, nasolabial folds and periauricular), acral and intertriginous areas, with irritability and failure to thrive. Her mother had been treated with isoniazid since the third trimester because of family contact with tuberculosis. Based on a diagnosis of suspected impetiginised eczema, the infant was treated with flucloxacillin and prednisolone, and maternal isoniazid was suspended, with no improvement. Investigations found low serum zinc levels in the infant (33 μg/dL; normal range (NR) >60 μg/dL), normal plasma zinc levels in the mother (111.3 μg/dL; NR 68-120 μg/dL) and lower than the normal range of zinc levels in breast milk (270μg/L; NR 1000-2500 μg/L), suggesting acrodermatitis caused by zinc deficiency. Oral zinc supplementation (3 mg/kg/day) was started with a marked improvement in skin lesions, as well as good weight gain. At the age of 6 months, after food diversification, supplementation was suspended, without any recurrence of symptoms. |
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Transient Symptomatic Zinc Deficiency in an Exclusively Breastfed InfantAcrodermatitis* / diagnosisAcrodermatitis* / drug therapyAcrodermatitis* / etiologyBreast FeedingInfantMalnutrition*Milk, Human / chemistryZincHDE PEDA 3-month-old, full term female infant, adequate for gestational age, and exclusively breastfed, was admitted with a 10 day history of generalised scaling erythematous dermatitis, affecting the face (perinasal, nasolabial folds and periauricular), acral and intertriginous areas, with irritability and failure to thrive. Her mother had been treated with isoniazid since the third trimester because of family contact with tuberculosis. Based on a diagnosis of suspected impetiginised eczema, the infant was treated with flucloxacillin and prednisolone, and maternal isoniazid was suspended, with no improvement. Investigations found low serum zinc levels in the infant (33 μg/dL; normal range (NR) >60 μg/dL), normal plasma zinc levels in the mother (111.3 μg/dL; NR 68-120 μg/dL) and lower than the normal range of zinc levels in breast milk (270μg/L; NR 1000-2500 μg/L), suggesting acrodermatitis caused by zinc deficiency. Oral zinc supplementation (3 mg/kg/day) was started with a marked improvement in skin lesions, as well as good weight gain. At the age of 6 months, after food diversification, supplementation was suspended, without any recurrence of symptoms.BMJRepositório do Centro Hospitalar Universitário de Lisboa Central, EPECrisóstomo, MSantos, MCTavares, ECunha, F2023-09-11T12:22:52Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/4694engBMJ Case Rep . 2021 Jun 30;14(6):e241754.10.1136/bcr-2021-241754info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-09-17T06:26:50Zoai:repositorio.chlc.min-saude.pt:10400.17/4694Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:29:29.419515Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Transient Symptomatic Zinc Deficiency in an Exclusively Breastfed Infant |
title |
Transient Symptomatic Zinc Deficiency in an Exclusively Breastfed Infant |
spellingShingle |
Transient Symptomatic Zinc Deficiency in an Exclusively Breastfed Infant Crisóstomo, M Acrodermatitis* / diagnosis Acrodermatitis* / drug therapy Acrodermatitis* / etiology Breast Feeding Infant Malnutrition* Milk, Human / chemistry Zinc HDE PED |
title_short |
Transient Symptomatic Zinc Deficiency in an Exclusively Breastfed Infant |
title_full |
Transient Symptomatic Zinc Deficiency in an Exclusively Breastfed Infant |
title_fullStr |
Transient Symptomatic Zinc Deficiency in an Exclusively Breastfed Infant |
title_full_unstemmed |
Transient Symptomatic Zinc Deficiency in an Exclusively Breastfed Infant |
title_sort |
Transient Symptomatic Zinc Deficiency in an Exclusively Breastfed Infant |
author |
Crisóstomo, M |
author_facet |
Crisóstomo, M Santos, MC Tavares, E Cunha, F |
author_role |
author |
author2 |
Santos, MC Tavares, E Cunha, F |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Crisóstomo, M Santos, MC Tavares, E Cunha, F |
dc.subject.por.fl_str_mv |
Acrodermatitis* / diagnosis Acrodermatitis* / drug therapy Acrodermatitis* / etiology Breast Feeding Infant Malnutrition* Milk, Human / chemistry Zinc HDE PED |
topic |
Acrodermatitis* / diagnosis Acrodermatitis* / drug therapy Acrodermatitis* / etiology Breast Feeding Infant Malnutrition* Milk, Human / chemistry Zinc HDE PED |
description |
A 3-month-old, full term female infant, adequate for gestational age, and exclusively breastfed, was admitted with a 10 day history of generalised scaling erythematous dermatitis, affecting the face (perinasal, nasolabial folds and periauricular), acral and intertriginous areas, with irritability and failure to thrive. Her mother had been treated with isoniazid since the third trimester because of family contact with tuberculosis. Based on a diagnosis of suspected impetiginised eczema, the infant was treated with flucloxacillin and prednisolone, and maternal isoniazid was suspended, with no improvement. Investigations found low serum zinc levels in the infant (33 μg/dL; normal range (NR) >60 μg/dL), normal plasma zinc levels in the mother (111.3 μg/dL; NR 68-120 μg/dL) and lower than the normal range of zinc levels in breast milk (270μg/L; NR 1000-2500 μg/L), suggesting acrodermatitis caused by zinc deficiency. Oral zinc supplementation (3 mg/kg/day) was started with a marked improvement in skin lesions, as well as good weight gain. At the age of 6 months, after food diversification, supplementation was suspended, without any recurrence of symptoms. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021 2021-01-01T00:00:00Z 2023-09-11T12:22:52Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/4694 |
url |
http://hdl.handle.net/10400.17/4694 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
BMJ Case Rep . 2021 Jun 30;14(6):e241754. 10.1136/bcr-2021-241754 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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BMJ |
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BMJ |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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