Design and fabrication of SiO2/TiO2 and MgO/TiO2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/37906 |
Resumo: | This paper presents the design, optimization and fabrication of 16 MgO/TiO2 and SiO2/TiO2 based high selective narrow bandpass optical filters. Their performance to extract diffuse reflectance and fluorescence signals from gastrointestinal tissue phantoms was successfully evaluated. The obtained results prove their feasibility to correctly extract those spectroscopic signals, through a Spearman’s rank correlation test (Spearman’s correlation coefficient higher than 0.981) performed between the original spectra and the ones obtained using those 16 fabricated optical filters. These results are an important step for the implementation of a miniaturized, low-cost and minimal invasive microsystem that could help in the detection of gastrointestinal dysplasia. |
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Design and fabrication of SiO2/TiO2 and MgO/TiO2 based high selective optical filters for diffuse reflectance and fluorescence signals extractionSpectroscopyOptical filtersGastrointestinal cancerEarly detectionFabry-PerotMedical optics instrumentationTissue diagnosticsDeposition and fabricationMaterials and process characterizationSpectroscopy, tissue diagnosticsCiências Médicas::Outras Ciências MédicasEngenharia e Tecnologia::Engenharia MédicaScience & TechnologyThis paper presents the design, optimization and fabrication of 16 MgO/TiO2 and SiO2/TiO2 based high selective narrow bandpass optical filters. Their performance to extract diffuse reflectance and fluorescence signals from gastrointestinal tissue phantoms was successfully evaluated. The obtained results prove their feasibility to correctly extract those spectroscopic signals, through a Spearman’s rank correlation test (Spearman’s correlation coefficient higher than 0.981) performed between the original spectra and the ones obtained using those 16 fabricated optical filters. These results are an important step for the implementation of a miniaturized, low-cost and minimal invasive microsystem that could help in the detection of gastrointestinal dysplasia.This work is funded by FEDER funds through the “Eixo I do Programa Operacional Fatores de Competitividade” (POFC) QREN, project reference COMPETE: FCOMP-01-0124- FEDER-020241 and by FCT—Fundação para a Ciência e a Tecnologia, project reference PTDC/EBB-EBI/120334/2010. The authors thank to the PEst-C/FIS/UI0607/2013 for the use of spectroscopic equipment. The authors also thank to V. Pinto from CMEMS-UMinho for the support during the profilometry measurements. S.P. thanks the FCT for the SFRH/BD/87605/2012 PhD grant.Optical Society of AmericaUniversidade do MinhoPimenta, SaraCardoso, S.Miranda, A.De Beule, P.Castanheira, Elisabete M. S.Minas, Graça2015-08-012015-08-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/37906engPimenta, S., Cardoso, S., Miranda, A., De Beule, P., Castanheira, E. M. S., & Minas, G. (2015). Design and fabrication of SiO 2/TiO 2 and MgO/TiO 2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction. Biomedical optics express, 6(8), 3084-30982156-708510.1364/BOE.6.003084https://www.osapublishing.org/boe/abstract.cfm?uri=boe-6-8-3084info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:40:05Zoai:repositorium.sdum.uminho.pt:1822/37906Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:36:48.902333Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Design and fabrication of SiO2/TiO2 and MgO/TiO2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction |
title |
Design and fabrication of SiO2/TiO2 and MgO/TiO2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction |
spellingShingle |
Design and fabrication of SiO2/TiO2 and MgO/TiO2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction Pimenta, Sara Spectroscopy Optical filters Gastrointestinal cancer Early detection Fabry-Perot Medical optics instrumentation Tissue diagnostics Deposition and fabrication Materials and process characterization Spectroscopy, tissue diagnostics Ciências Médicas::Outras Ciências Médicas Engenharia e Tecnologia::Engenharia Médica Science & Technology |
title_short |
Design and fabrication of SiO2/TiO2 and MgO/TiO2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction |
title_full |
Design and fabrication of SiO2/TiO2 and MgO/TiO2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction |
title_fullStr |
Design and fabrication of SiO2/TiO2 and MgO/TiO2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction |
title_full_unstemmed |
Design and fabrication of SiO2/TiO2 and MgO/TiO2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction |
title_sort |
Design and fabrication of SiO2/TiO2 and MgO/TiO2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction |
author |
Pimenta, Sara |
author_facet |
Pimenta, Sara Cardoso, S. Miranda, A. De Beule, P. Castanheira, Elisabete M. S. Minas, Graça |
author_role |
author |
author2 |
Cardoso, S. Miranda, A. De Beule, P. Castanheira, Elisabete M. S. Minas, Graça |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Pimenta, Sara Cardoso, S. Miranda, A. De Beule, P. Castanheira, Elisabete M. S. Minas, Graça |
dc.subject.por.fl_str_mv |
Spectroscopy Optical filters Gastrointestinal cancer Early detection Fabry-Perot Medical optics instrumentation Tissue diagnostics Deposition and fabrication Materials and process characterization Spectroscopy, tissue diagnostics Ciências Médicas::Outras Ciências Médicas Engenharia e Tecnologia::Engenharia Médica Science & Technology |
topic |
Spectroscopy Optical filters Gastrointestinal cancer Early detection Fabry-Perot Medical optics instrumentation Tissue diagnostics Deposition and fabrication Materials and process characterization Spectroscopy, tissue diagnostics Ciências Médicas::Outras Ciências Médicas Engenharia e Tecnologia::Engenharia Médica Science & Technology |
description |
This paper presents the design, optimization and fabrication of 16 MgO/TiO2 and SiO2/TiO2 based high selective narrow bandpass optical filters. Their performance to extract diffuse reflectance and fluorescence signals from gastrointestinal tissue phantoms was successfully evaluated. The obtained results prove their feasibility to correctly extract those spectroscopic signals, through a Spearman’s rank correlation test (Spearman’s correlation coefficient higher than 0.981) performed between the original spectra and the ones obtained using those 16 fabricated optical filters. These results are an important step for the implementation of a miniaturized, low-cost and minimal invasive microsystem that could help in the detection of gastrointestinal dysplasia. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-08-01 2015-08-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/37906 |
url |
http://hdl.handle.net/1822/37906 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Pimenta, S., Cardoso, S., Miranda, A., De Beule, P., Castanheira, E. M. S., & Minas, G. (2015). Design and fabrication of SiO 2/TiO 2 and MgO/TiO 2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction. Biomedical optics express, 6(8), 3084-3098 2156-7085 10.1364/BOE.6.003084 https://www.osapublishing.org/boe/abstract.cfm?uri=boe-6-8-3084 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Optical Society of America |
publisher.none.fl_str_mv |
Optical Society of America |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799132898759016448 |