Substantive antimicrobial activity in chlorhexidine-treated human root dentin
Autor(a) principal: | |
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Data de Publicação: | 2002 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/4823 https://doi.org/10.1067/moe.2002.124002 |
Resumo: | Objective. The aim of this in vitro study was to assess the substantive antimicrobial activity of different medicaments in human root dentin. Study Design. Canals of 98 roots were enlarged to standard size and medicated for 7 days with the following: (1) 2% chlorhexidine (CHX) gel, (2) 0.2% CHX gel, (3) 2% CHX solution, (4) Ca(OH)2, (5) Ca(OH)2+ 0.2% CHX gel, (6) 2% CHX solution + a 25% CHX-containing controlled-release device, (7) saline, and (8) gel vehicle. After medication, canals were inoculated with Enterococcus faecalis for 21 days. Dentin samples were collected with Gates-Glidden burs into brain heart infusion broth, and bacterial growth was assessed with spectrophotometric analysis of optical density after 72 hours of incubation. Results. Mean optical densities were significantly lower for groups with 2% CHX (1, 3, and 6) when compared with those of the controls (P < .05, analysis of variance with the Tukey test). Other groups did not differ significantly from the controls. Conclusions. Canal dressing for 1 week with 2% CHX may provide residual antimicrobial activity against E faecalis. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;94:240-5) |
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Substantive antimicrobial activity in chlorhexidine-treated human root dentinObjective. The aim of this in vitro study was to assess the substantive antimicrobial activity of different medicaments in human root dentin. Study Design. Canals of 98 roots were enlarged to standard size and medicated for 7 days with the following: (1) 2% chlorhexidine (CHX) gel, (2) 0.2% CHX gel, (3) 2% CHX solution, (4) Ca(OH)2, (5) Ca(OH)2+ 0.2% CHX gel, (6) 2% CHX solution + a 25% CHX-containing controlled-release device, (7) saline, and (8) gel vehicle. After medication, canals were inoculated with Enterococcus faecalis for 21 days. Dentin samples were collected with Gates-Glidden burs into brain heart infusion broth, and bacterial growth was assessed with spectrophotometric analysis of optical density after 72 hours of incubation. Results. Mean optical densities were significantly lower for groups with 2% CHX (1, 3, and 6) when compared with those of the controls (P < .05, analysis of variance with the Tukey test). Other groups did not differ significantly from the controls. Conclusions. Canal dressing for 1 week with 2% CHX may provide residual antimicrobial activity against E faecalis. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;94:240-5)http://www.sciencedirect.com/science/article/B6WP1-46X29WN-22/1/fa5d5f0440739290f0e14484cbb9abb02002info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleaplication/PDFhttp://hdl.handle.net/10316/4823http://hdl.handle.net/10316/4823https://doi.org/10.1067/moe.2002.124002engOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontics. 94:2 (2002) 240-245Basrani, BettinaSantos, J. MiguelTjäderhane, LeoGrad, HelenGorduysus, OmerHuang, JunfuLawrence, Herenia P.Friedman, Shimoninfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-05-25T03:03:11Zoai:estudogeral.uc.pt:10316/4823Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:43:35.871471Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Substantive antimicrobial activity in chlorhexidine-treated human root dentin |
title |
Substantive antimicrobial activity in chlorhexidine-treated human root dentin |
spellingShingle |
Substantive antimicrobial activity in chlorhexidine-treated human root dentin Basrani, Bettina |
title_short |
Substantive antimicrobial activity in chlorhexidine-treated human root dentin |
title_full |
Substantive antimicrobial activity in chlorhexidine-treated human root dentin |
title_fullStr |
Substantive antimicrobial activity in chlorhexidine-treated human root dentin |
title_full_unstemmed |
Substantive antimicrobial activity in chlorhexidine-treated human root dentin |
title_sort |
Substantive antimicrobial activity in chlorhexidine-treated human root dentin |
author |
Basrani, Bettina |
author_facet |
Basrani, Bettina Santos, J. Miguel Tjäderhane, Leo Grad, Helen Gorduysus, Omer Huang, Junfu Lawrence, Herenia P. Friedman, Shimon |
author_role |
author |
author2 |
Santos, J. Miguel Tjäderhane, Leo Grad, Helen Gorduysus, Omer Huang, Junfu Lawrence, Herenia P. Friedman, Shimon |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Basrani, Bettina Santos, J. Miguel Tjäderhane, Leo Grad, Helen Gorduysus, Omer Huang, Junfu Lawrence, Herenia P. Friedman, Shimon |
description |
Objective. The aim of this in vitro study was to assess the substantive antimicrobial activity of different medicaments in human root dentin. Study Design. Canals of 98 roots were enlarged to standard size and medicated for 7 days with the following: (1) 2% chlorhexidine (CHX) gel, (2) 0.2% CHX gel, (3) 2% CHX solution, (4) Ca(OH)2, (5) Ca(OH)2+ 0.2% CHX gel, (6) 2% CHX solution + a 25% CHX-containing controlled-release device, (7) saline, and (8) gel vehicle. After medication, canals were inoculated with Enterococcus faecalis for 21 days. Dentin samples were collected with Gates-Glidden burs into brain heart infusion broth, and bacterial growth was assessed with spectrophotometric analysis of optical density after 72 hours of incubation. Results. Mean optical densities were significantly lower for groups with 2% CHX (1, 3, and 6) when compared with those of the controls (P < .05, analysis of variance with the Tukey test). Other groups did not differ significantly from the controls. Conclusions. Canal dressing for 1 week with 2% CHX may provide residual antimicrobial activity against E faecalis. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;94:240-5) |
publishDate |
2002 |
dc.date.none.fl_str_mv |
2002 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/4823 http://hdl.handle.net/10316/4823 https://doi.org/10.1067/moe.2002.124002 |
url |
http://hdl.handle.net/10316/4823 https://doi.org/10.1067/moe.2002.124002 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontics. 94:2 (2002) 240-245 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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aplication/PDF |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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