Supramolecular photochemistry of encapsulated caged ortho-nitrobenzyl triggers

Detalhes bibliográficos
Autor(a) principal: Kamatham, Nareshbabu
Data de Publicação: 2019
Outros Autores: Raj, A. Mohan, Givens, Richard S., Da Silva, José Paulo, Ramamurthy, V.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.1/14233
Resumo: ortho-Nitrobenzyl (oNB) triggers have been extensively used to release various molecules of interest. However, the toxicity and reactivity of the spent chromophore, o-nitrosobenzaldehyde, remains an unaddressed difficulty. In this study we have applied the well-established supramolecular photochemical concepts to retain the spent trigger o-nitrosobenzaldehyde within the organic capsule after release of water-soluble acids and alcohols. The sequestering power of organic capsules for spent chromophores during photorelease from ortho-nitrobenzyl esters, ethers and alcohols is demonstrated with several examples.
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spelling Supramolecular photochemistry of encapsulated caged ortho-nitrobenzyl triggersPhotoremovable protecting groupsReaction-Mechanisms2-Nitrobenzyl compoundsGuest moleculesCapsuleplexPhotoreleaseContainersSystemEstersWaterortho-Nitrobenzyl (oNB) triggers have been extensively used to release various molecules of interest. However, the toxicity and reactivity of the spent chromophore, o-nitrosobenzaldehyde, remains an unaddressed difficulty. In this study we have applied the well-established supramolecular photochemical concepts to retain the spent trigger o-nitrosobenzaldehyde within the organic capsule after release of water-soluble acids and alcohols. The sequestering power of organic capsules for spent chromophores during photorelease from ortho-nitrobenzyl esters, ethers and alcohols is demonstrated with several examples.National Science FoundationNational Science Foundation (NSF) [CHE-1807729]Kansas University Endowment AssociationFCT - Foundation for Science and TechnologyPortuguese Foundation for Science and Technology [UID/Multi/04326/2019, EMBRC.PT ALG-01-0145-FEDER-022121]Royal Society of ChemistrySapientiaKamatham, NareshbabuRaj, A. MohanGivens, Richard S.Da Silva, José PauloRamamurthy, V.2020-07-24T10:51:27Z2019-102019-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/14233eng1474-905X10.1039/c9pp00260jinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-24T10:26:30Zoai:sapientia.ualg.pt:10400.1/14233Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:05:16.476541Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Supramolecular photochemistry of encapsulated caged ortho-nitrobenzyl triggers
title Supramolecular photochemistry of encapsulated caged ortho-nitrobenzyl triggers
spellingShingle Supramolecular photochemistry of encapsulated caged ortho-nitrobenzyl triggers
Kamatham, Nareshbabu
Photoremovable protecting groups
Reaction-Mechanisms
2-Nitrobenzyl compounds
Guest molecules
Capsuleplex
Photorelease
Containers
System
Esters
Water
title_short Supramolecular photochemistry of encapsulated caged ortho-nitrobenzyl triggers
title_full Supramolecular photochemistry of encapsulated caged ortho-nitrobenzyl triggers
title_fullStr Supramolecular photochemistry of encapsulated caged ortho-nitrobenzyl triggers
title_full_unstemmed Supramolecular photochemistry of encapsulated caged ortho-nitrobenzyl triggers
title_sort Supramolecular photochemistry of encapsulated caged ortho-nitrobenzyl triggers
author Kamatham, Nareshbabu
author_facet Kamatham, Nareshbabu
Raj, A. Mohan
Givens, Richard S.
Da Silva, José Paulo
Ramamurthy, V.
author_role author
author2 Raj, A. Mohan
Givens, Richard S.
Da Silva, José Paulo
Ramamurthy, V.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Sapientia
dc.contributor.author.fl_str_mv Kamatham, Nareshbabu
Raj, A. Mohan
Givens, Richard S.
Da Silva, José Paulo
Ramamurthy, V.
dc.subject.por.fl_str_mv Photoremovable protecting groups
Reaction-Mechanisms
2-Nitrobenzyl compounds
Guest molecules
Capsuleplex
Photorelease
Containers
System
Esters
Water
topic Photoremovable protecting groups
Reaction-Mechanisms
2-Nitrobenzyl compounds
Guest molecules
Capsuleplex
Photorelease
Containers
System
Esters
Water
description ortho-Nitrobenzyl (oNB) triggers have been extensively used to release various molecules of interest. However, the toxicity and reactivity of the spent chromophore, o-nitrosobenzaldehyde, remains an unaddressed difficulty. In this study we have applied the well-established supramolecular photochemical concepts to retain the spent trigger o-nitrosobenzaldehyde within the organic capsule after release of water-soluble acids and alcohols. The sequestering power of organic capsules for spent chromophores during photorelease from ortho-nitrobenzyl esters, ethers and alcohols is demonstrated with several examples.
publishDate 2019
dc.date.none.fl_str_mv 2019-10
2019-10-01T00:00:00Z
2020-07-24T10:51:27Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.1/14233
url http://hdl.handle.net/10400.1/14233
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1474-905X
10.1039/c9pp00260j
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry
publisher.none.fl_str_mv Royal Society of Chemistry
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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