Comparison of two simulators for individual based models in HIV epidemiology in a population with HSV 2 in Yaoundé (Cameroon)

Detalhes bibliográficos
Autor(a) principal: Hendrickx, Diana M.
Data de Publicação: 2021
Outros Autores: Sousa, João Dinis, Libin, Pieter J.K., Delva, Wim, Liesenborgs, Jori, Hens, Niel, Müller, Viktor, Vandamme, Anne Mieke
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/122440
Resumo: Funding Information: The research conducted by D.M.H. and N.H. in this study was funded by the Fonds Wetenschappelijk Onder-zoek—Vlaanderen (Research Foundation—Flanders; FWO, http://www.fwo.be/en/) (Grant Agreements G0E8416N and G0B2317N). The research done by J.D.S. and A.M.V. in this study has been supported in part by Grants G.0692.14 and G0B2317N, funded by the FWO, Belgium. P.J.K.L. was supported By a PhD Grant of the FWO (1S31916N), and is currently funded via a post-doctoral fellowship (1242021N) of the FWO. WD was supported by a postdoctoral fellowship from FWO (12L5816N). Research done by V.M. in this study has been completed as part of the ELTE Thematic Excellence Programme 2020 supported by the National Research, Development and Innovation Office (TKP2020-IKA-05). The authors gratefully acknowledge support from the FWO Scientific Research Community on Network Statistics for Sexually Transmitted Diseases Epidemiology. The computational resources and services used in this work were provided by the VSC (Flemish Supercomputer Center), funded by the Research Foundation—Flanders (FWO) and the Flemish Government—department EWI. Publisher Copyright: © 2021, The Author(s).
id RCAP_3f455510e0528746eccfe28b28b869a0
oai_identifier_str oai:run.unl.pt:10362/122440
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Comparison of two simulators for individual based models in HIV epidemiology in a population with HSV 2 in Yaoundé (Cameroon)VirologyInfectious DiseasesSDG 3 - Good Health and Well-beingFunding Information: The research conducted by D.M.H. and N.H. in this study was funded by the Fonds Wetenschappelijk Onder-zoek—Vlaanderen (Research Foundation—Flanders; FWO, http://www.fwo.be/en/) (Grant Agreements G0E8416N and G0B2317N). The research done by J.D.S. and A.M.V. in this study has been supported in part by Grants G.0692.14 and G0B2317N, funded by the FWO, Belgium. P.J.K.L. was supported By a PhD Grant of the FWO (1S31916N), and is currently funded via a post-doctoral fellowship (1242021N) of the FWO. WD was supported by a postdoctoral fellowship from FWO (12L5816N). Research done by V.M. in this study has been completed as part of the ELTE Thematic Excellence Programme 2020 supported by the National Research, Development and Innovation Office (TKP2020-IKA-05). The authors gratefully acknowledge support from the FWO Scientific Research Community on Network Statistics for Sexually Transmitted Diseases Epidemiology. The computational resources and services used in this work were provided by the VSC (Flemish Supercomputer Center), funded by the Research Foundation—Flanders (FWO) and the Flemish Government—department EWI. Publisher Copyright: © 2021, The Author(s).Model comparisons have been widely used to guide intervention strategies to control infectious diseases. Agreement between different models is crucial for providing robust evidence for policy-makers because differences in model properties can influence their predictions. In this study, we compared models implemented by two individual-based model simulators for HIV epidemiology in a heterosexual population with Herpes simplex virus type-2 (HSV-2). For each model simulator, we constructed four models, starting from a simplified basic model and stepwise including more model complexity. For the resulting eight models, the predictions of the impact of behavioural interventions on the HIV epidemic in Yaoundé-Cameroon were compared. The results show that differences in model assumptions and model complexity can influence the size of the predicted impact of the intervention, as well as the predicted qualitative behaviour of the HIV epidemic after the intervention. These differences in predictions of an intervention were also observed for two models that agreed in their predictions of the HIV epidemic in the absence of that intervention. Without additional data, it is impossible to determine which of these two models is the most reliable. These findings highlight the importance of making more data available for the calibration and validation of epidemiological models.Global Health and Tropical Medicine (GHTM)Instituto de Higiene e Medicina Tropical (IHMT)TB, HIV and opportunistic diseases and pathogens (THOP)RUNHendrickx, Diana M.Sousa, João DinisLibin, Pieter J.K.Delva, WimLiesenborgs, JoriHens, NielMüller, ViktorVandamme, Anne Mieke2021-08-12T23:20:41Z2021-122021-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/122440eng2045-2322PURE: 33050432https://doi.org/10.1038/s41598-021-94289-zinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:04:08Zoai:run.unl.pt:10362/122440Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:44:47.426250Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Comparison of two simulators for individual based models in HIV epidemiology in a population with HSV 2 in Yaoundé (Cameroon)
title Comparison of two simulators for individual based models in HIV epidemiology in a population with HSV 2 in Yaoundé (Cameroon)
spellingShingle Comparison of two simulators for individual based models in HIV epidemiology in a population with HSV 2 in Yaoundé (Cameroon)
Hendrickx, Diana M.
Virology
Infectious Diseases
SDG 3 - Good Health and Well-being
title_short Comparison of two simulators for individual based models in HIV epidemiology in a population with HSV 2 in Yaoundé (Cameroon)
title_full Comparison of two simulators for individual based models in HIV epidemiology in a population with HSV 2 in Yaoundé (Cameroon)
title_fullStr Comparison of two simulators for individual based models in HIV epidemiology in a population with HSV 2 in Yaoundé (Cameroon)
title_full_unstemmed Comparison of two simulators for individual based models in HIV epidemiology in a population with HSV 2 in Yaoundé (Cameroon)
title_sort Comparison of two simulators for individual based models in HIV epidemiology in a population with HSV 2 in Yaoundé (Cameroon)
author Hendrickx, Diana M.
author_facet Hendrickx, Diana M.
Sousa, João Dinis
Libin, Pieter J.K.
Delva, Wim
Liesenborgs, Jori
Hens, Niel
Müller, Viktor
Vandamme, Anne Mieke
author_role author
author2 Sousa, João Dinis
Libin, Pieter J.K.
Delva, Wim
Liesenborgs, Jori
Hens, Niel
Müller, Viktor
Vandamme, Anne Mieke
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Global Health and Tropical Medicine (GHTM)
Instituto de Higiene e Medicina Tropical (IHMT)
TB, HIV and opportunistic diseases and pathogens (THOP)
RUN
dc.contributor.author.fl_str_mv Hendrickx, Diana M.
Sousa, João Dinis
Libin, Pieter J.K.
Delva, Wim
Liesenborgs, Jori
Hens, Niel
Müller, Viktor
Vandamme, Anne Mieke
dc.subject.por.fl_str_mv Virology
Infectious Diseases
SDG 3 - Good Health and Well-being
topic Virology
Infectious Diseases
SDG 3 - Good Health and Well-being
description Funding Information: The research conducted by D.M.H. and N.H. in this study was funded by the Fonds Wetenschappelijk Onder-zoek—Vlaanderen (Research Foundation—Flanders; FWO, http://www.fwo.be/en/) (Grant Agreements G0E8416N and G0B2317N). The research done by J.D.S. and A.M.V. in this study has been supported in part by Grants G.0692.14 and G0B2317N, funded by the FWO, Belgium. P.J.K.L. was supported By a PhD Grant of the FWO (1S31916N), and is currently funded via a post-doctoral fellowship (1242021N) of the FWO. WD was supported by a postdoctoral fellowship from FWO (12L5816N). Research done by V.M. in this study has been completed as part of the ELTE Thematic Excellence Programme 2020 supported by the National Research, Development and Innovation Office (TKP2020-IKA-05). The authors gratefully acknowledge support from the FWO Scientific Research Community on Network Statistics for Sexually Transmitted Diseases Epidemiology. The computational resources and services used in this work were provided by the VSC (Flemish Supercomputer Center), funded by the Research Foundation—Flanders (FWO) and the Flemish Government—department EWI. Publisher Copyright: © 2021, The Author(s).
publishDate 2021
dc.date.none.fl_str_mv 2021-08-12T23:20:41Z
2021-12
2021-12-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/122440
url http://hdl.handle.net/10362/122440
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2045-2322
PURE: 33050432
https://doi.org/10.1038/s41598-021-94289-z
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799138054703677440

Registros relacionados