Atypical functional connectivity during unfamiliar music listening in children with autism
Autor(a) principal: | |
---|---|
Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.13/4319 |
Resumo: | Background: Atypical processing of unfamiliar, but less so familiar, stimuli has been described in Autism Spectrum Disorder (ASD), in particular in relation to face processing. We examined the construct of familiarity in ASD using familiar and unfamiliar songs, to investigate the link between familiarity and autism symptoms, such as repetitive behavior. Methods: Forty-eight children, 24 with ASD (21 males, mean age = 9.96 years ± 1.54) and 24 typically developing (TD) controls (21 males, mean age = 10.17 ± 1.90) completed a music familiarity task using individually identified familiar compared to unfamiliar songs, while magnetoencephalography (MEG) was recorded. Each song was presented for 30 s. We used both amplitude envelope correlation (AEC) and the weighted phase lag index (wPLI) to assess functional connectivity between specific regions of interest (ROI) and non-ROI parcels, as well as at the whole brain level, to understand what is preserved and what is impaired in familiar music listening in this population. Results: Increased wPLI synchronization for familiar vs. unfamiliar music was found for typically developing children in the gamma frequency. There were no significant differences within the ASD group for this comparison. During the processing of unfamiliar music, we demonstrated left lateralized increased theta and beta band connectivity in children with ASD compared to controls. An interaction effect found greater alpha band connectivity in the TD group compared to ASD to unfamiliar music only, anchored in the left insula.Conclusion: Our results revealed atypical processing of unfamiliar songs in children with ASD, consistent with previous studies in other modalities reporting that processing novelty is a challenge for ASD. Relatively typical processing of familiar stimuli may represent a strength and may be of interest to strength-based intervention planning. |
id |
RCAP_3f60763b8119f0904fa6defcaeff36e4 |
---|---|
oai_identifier_str |
oai:digituma.uma.pt:10400.13/4319 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Atypical functional connectivity during unfamiliar music listening in children with autismAutism spectrum disorderMusicFamiliarity processingMagnetoencephalographyNeural oscillationFunctional connectivity.Faculdade de Ciências da VidaBackground: Atypical processing of unfamiliar, but less so familiar, stimuli has been described in Autism Spectrum Disorder (ASD), in particular in relation to face processing. We examined the construct of familiarity in ASD using familiar and unfamiliar songs, to investigate the link between familiarity and autism symptoms, such as repetitive behavior. Methods: Forty-eight children, 24 with ASD (21 males, mean age = 9.96 years ± 1.54) and 24 typically developing (TD) controls (21 males, mean age = 10.17 ± 1.90) completed a music familiarity task using individually identified familiar compared to unfamiliar songs, while magnetoencephalography (MEG) was recorded. Each song was presented for 30 s. We used both amplitude envelope correlation (AEC) and the weighted phase lag index (wPLI) to assess functional connectivity between specific regions of interest (ROI) and non-ROI parcels, as well as at the whole brain level, to understand what is preserved and what is impaired in familiar music listening in this population. Results: Increased wPLI synchronization for familiar vs. unfamiliar music was found for typically developing children in the gamma frequency. There were no significant differences within the ASD group for this comparison. During the processing of unfamiliar music, we demonstrated left lateralized increased theta and beta band connectivity in children with ASD compared to controls. An interaction effect found greater alpha band connectivity in the TD group compared to ASD to unfamiliar music only, anchored in the left insula.Conclusion: Our results revealed atypical processing of unfamiliar songs in children with ASD, consistent with previous studies in other modalities reporting that processing novelty is a challenge for ASD. Relatively typical processing of familiar stimuli may represent a strength and may be of interest to strength-based intervention planning.Frontiers MediaDigitUMaFreitas, CarinaHunt, Benjamin A. E.Wong, Simeon M.Ristic, LeanneFragiadakis, SusanChow, StephanieIaboni, AlanaBrian, JessicaSoorya, LathaChen, Joyce L.Schachar, RussellDunkley, Benjamin T.Taylor, Margot J.Lerch, Jason P.Anagnostou, Evdokia2022-06-09T09:19:59Z2022-01-01T00:00:00Z2022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.13/4319engFreitas, C., Hunt, B. A., Wong, S. M., Ristic, L., Fragiadakis, S., Chow, S., ... & Anagnostou, E. (2022). Atypical functional connectivity during unfamiliar music listening in children with autism. Frontiers in neuroscience, 16. doi: 10.3389/fnins.2022.82941510.3389/fnins.2022.829415info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-05T12:57:36Zoai:digituma.uma.pt:10400.13/4319Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:08:14.702243Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Atypical functional connectivity during unfamiliar music listening in children with autism |
title |
Atypical functional connectivity during unfamiliar music listening in children with autism |
spellingShingle |
Atypical functional connectivity during unfamiliar music listening in children with autism Freitas, Carina Autism spectrum disorder Music Familiarity processing Magnetoencephalography Neural oscillation Functional connectivity . Faculdade de Ciências da Vida |
title_short |
Atypical functional connectivity during unfamiliar music listening in children with autism |
title_full |
Atypical functional connectivity during unfamiliar music listening in children with autism |
title_fullStr |
Atypical functional connectivity during unfamiliar music listening in children with autism |
title_full_unstemmed |
Atypical functional connectivity during unfamiliar music listening in children with autism |
title_sort |
Atypical functional connectivity during unfamiliar music listening in children with autism |
author |
Freitas, Carina |
author_facet |
Freitas, Carina Hunt, Benjamin A. E. Wong, Simeon M. Ristic, Leanne Fragiadakis, Susan Chow, Stephanie Iaboni, Alana Brian, Jessica Soorya, Latha Chen, Joyce L. Schachar, Russell Dunkley, Benjamin T. Taylor, Margot J. Lerch, Jason P. Anagnostou, Evdokia |
author_role |
author |
author2 |
Hunt, Benjamin A. E. Wong, Simeon M. Ristic, Leanne Fragiadakis, Susan Chow, Stephanie Iaboni, Alana Brian, Jessica Soorya, Latha Chen, Joyce L. Schachar, Russell Dunkley, Benjamin T. Taylor, Margot J. Lerch, Jason P. Anagnostou, Evdokia |
author2_role |
author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
DigitUMa |
dc.contributor.author.fl_str_mv |
Freitas, Carina Hunt, Benjamin A. E. Wong, Simeon M. Ristic, Leanne Fragiadakis, Susan Chow, Stephanie Iaboni, Alana Brian, Jessica Soorya, Latha Chen, Joyce L. Schachar, Russell Dunkley, Benjamin T. Taylor, Margot J. Lerch, Jason P. Anagnostou, Evdokia |
dc.subject.por.fl_str_mv |
Autism spectrum disorder Music Familiarity processing Magnetoencephalography Neural oscillation Functional connectivity . Faculdade de Ciências da Vida |
topic |
Autism spectrum disorder Music Familiarity processing Magnetoencephalography Neural oscillation Functional connectivity . Faculdade de Ciências da Vida |
description |
Background: Atypical processing of unfamiliar, but less so familiar, stimuli has been described in Autism Spectrum Disorder (ASD), in particular in relation to face processing. We examined the construct of familiarity in ASD using familiar and unfamiliar songs, to investigate the link between familiarity and autism symptoms, such as repetitive behavior. Methods: Forty-eight children, 24 with ASD (21 males, mean age = 9.96 years ± 1.54) and 24 typically developing (TD) controls (21 males, mean age = 10.17 ± 1.90) completed a music familiarity task using individually identified familiar compared to unfamiliar songs, while magnetoencephalography (MEG) was recorded. Each song was presented for 30 s. We used both amplitude envelope correlation (AEC) and the weighted phase lag index (wPLI) to assess functional connectivity between specific regions of interest (ROI) and non-ROI parcels, as well as at the whole brain level, to understand what is preserved and what is impaired in familiar music listening in this population. Results: Increased wPLI synchronization for familiar vs. unfamiliar music was found for typically developing children in the gamma frequency. There were no significant differences within the ASD group for this comparison. During the processing of unfamiliar music, we demonstrated left lateralized increased theta and beta band connectivity in children with ASD compared to controls. An interaction effect found greater alpha band connectivity in the TD group compared to ASD to unfamiliar music only, anchored in the left insula.Conclusion: Our results revealed atypical processing of unfamiliar songs in children with ASD, consistent with previous studies in other modalities reporting that processing novelty is a challenge for ASD. Relatively typical processing of familiar stimuli may represent a strength and may be of interest to strength-based intervention planning. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-06-09T09:19:59Z 2022-01-01T00:00:00Z 2022-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.13/4319 |
url |
http://hdl.handle.net/10400.13/4319 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Freitas, C., Hunt, B. A., Wong, S. M., Ristic, L., Fragiadakis, S., Chow, S., ... & Anagnostou, E. (2022). Atypical functional connectivity during unfamiliar music listening in children with autism. Frontiers in neuroscience, 16. doi: 10.3389/fnins.2022.829415 10.3389/fnins.2022.829415 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Frontiers Media |
publisher.none.fl_str_mv |
Frontiers Media |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799129950494654464 |