On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds

Detalhes bibliográficos
Autor(a) principal: Baptista, Ricardo
Data de Publicação: 2020
Outros Autores: Guedes, Mafalda, Pereira, Manuel F. C., Maurício, António, Carrelo, Henrique, Cidade, Teresa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/115478
Resumo: FCT through IDMEC under LAETA, project UIDB/50022/2020; CeFEMA contract UID/CTM/04540/2019 ; Strategic Project Pest - C/CTM/LA0025/2011; CERENA Strategic Project UIDB/04028/2020 .
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spelling On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds3D printingBone replacementMechanical behaviorPorosityScaffoldsBiotechnologyBiomedical EngineeringComputer Science ApplicationsFCT through IDMEC under LAETA, project UIDB/50022/2020; CeFEMA contract UID/CTM/04540/2019 ; Strategic Project Pest - C/CTM/LA0025/2011; CERENA Strategic Project UIDB/04028/2020 .Tissue engineering is responsible for developing biological substitutes that restore, maintain or improve tissue function. A solution to achieve this is to implant scaffolds on the affected tissue. These support structures will be responsible for cell protection, oxygenation and nutrition, while supporting mechanical loads during the regeneration process. They should also be biodegradable in order to be gradually replaced by healthy tissue. From the available scaffolds manufacturing techniques, fused filament fabrication has been used recently. This technique does not use organic solvents and has the ability to produce complex geometries. In this paper the influence of manufacturing parameters was assessed. Different temperatures, extrusion speeds, filament offset distances and layer thicknesses were tested and their effect analyzed regarding scaffold morphology and mechanical properties. By decreasing the filament offset distance, three different scaffolds porosities were obtained, increasing the mechanical properties. Combining higher printing temperatures with slow extrusion speeds and low layer thickness, a maximum yield stress of 28 ​MPa and apparent compressive modulus of 942 ​MPa were obtained. With these preferred parameters, two different manufacturing schemes and geometries were tested. While using a double layer printing scheme one obtains an average of 70% increase in mechanical properties, using a staggered configuration can decrease mechanical properties up to 84%.CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)DCM - Departamento de Ciência dos MateriaisRUNBaptista, RicardoGuedes, MafaldaPereira, Manuel F. C.Maurício, AntónioCarrelo, HenriqueCidade, Teresa2022-09-07T00:31:42Z2020-122020-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/115478eng2405-8866PURE: 28879831https://doi.org/10.1016/j.bprint.2020.e00096info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:58:01Zoai:run.unl.pt:10362/115478Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:42:45.509459Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds
title On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds
spellingShingle On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds
Baptista, Ricardo
3D printing
Bone replacement
Mechanical behavior
Porosity
Scaffolds
Biotechnology
Biomedical Engineering
Computer Science Applications
title_short On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds
title_full On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds
title_fullStr On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds
title_full_unstemmed On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds
title_sort On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds
author Baptista, Ricardo
author_facet Baptista, Ricardo
Guedes, Mafalda
Pereira, Manuel F. C.
Maurício, António
Carrelo, Henrique
Cidade, Teresa
author_role author
author2 Guedes, Mafalda
Pereira, Manuel F. C.
Maurício, António
Carrelo, Henrique
Cidade, Teresa
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)
DCM - Departamento de Ciência dos Materiais
RUN
dc.contributor.author.fl_str_mv Baptista, Ricardo
Guedes, Mafalda
Pereira, Manuel F. C.
Maurício, António
Carrelo, Henrique
Cidade, Teresa
dc.subject.por.fl_str_mv 3D printing
Bone replacement
Mechanical behavior
Porosity
Scaffolds
Biotechnology
Biomedical Engineering
Computer Science Applications
topic 3D printing
Bone replacement
Mechanical behavior
Porosity
Scaffolds
Biotechnology
Biomedical Engineering
Computer Science Applications
description FCT through IDMEC under LAETA, project UIDB/50022/2020; CeFEMA contract UID/CTM/04540/2019 ; Strategic Project Pest - C/CTM/LA0025/2011; CERENA Strategic Project UIDB/04028/2020 .
publishDate 2020
dc.date.none.fl_str_mv 2020-12
2020-12-01T00:00:00Z
2022-09-07T00:31:42Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/115478
url http://hdl.handle.net/10362/115478
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2405-8866
PURE: 28879831
https://doi.org/10.1016/j.bprint.2020.e00096
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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