On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/115478 |
Resumo: | FCT through IDMEC under LAETA, project UIDB/50022/2020; CeFEMA contract UID/CTM/04540/2019 ; Strategic Project Pest - C/CTM/LA0025/2011; CERENA Strategic Project UIDB/04028/2020 . |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds3D printingBone replacementMechanical behaviorPorosityScaffoldsBiotechnologyBiomedical EngineeringComputer Science ApplicationsFCT through IDMEC under LAETA, project UIDB/50022/2020; CeFEMA contract UID/CTM/04540/2019 ; Strategic Project Pest - C/CTM/LA0025/2011; CERENA Strategic Project UIDB/04028/2020 .Tissue engineering is responsible for developing biological substitutes that restore, maintain or improve tissue function. A solution to achieve this is to implant scaffolds on the affected tissue. These support structures will be responsible for cell protection, oxygenation and nutrition, while supporting mechanical loads during the regeneration process. They should also be biodegradable in order to be gradually replaced by healthy tissue. From the available scaffolds manufacturing techniques, fused filament fabrication has been used recently. This technique does not use organic solvents and has the ability to produce complex geometries. In this paper the influence of manufacturing parameters was assessed. Different temperatures, extrusion speeds, filament offset distances and layer thicknesses were tested and their effect analyzed regarding scaffold morphology and mechanical properties. By decreasing the filament offset distance, three different scaffolds porosities were obtained, increasing the mechanical properties. Combining higher printing temperatures with slow extrusion speeds and low layer thickness, a maximum yield stress of 28 MPa and apparent compressive modulus of 942 MPa were obtained. With these preferred parameters, two different manufacturing schemes and geometries were tested. While using a double layer printing scheme one obtains an average of 70% increase in mechanical properties, using a staggered configuration can decrease mechanical properties up to 84%.CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)DCM - Departamento de Ciência dos MateriaisRUNBaptista, RicardoGuedes, MafaldaPereira, Manuel F. C.Maurício, AntónioCarrelo, HenriqueCidade, Teresa2022-09-07T00:31:42Z2020-122020-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/115478eng2405-8866PURE: 28879831https://doi.org/10.1016/j.bprint.2020.e00096info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:58:01Zoai:run.unl.pt:10362/115478Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:42:45.509459Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds |
title |
On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds |
spellingShingle |
On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds Baptista, Ricardo 3D printing Bone replacement Mechanical behavior Porosity Scaffolds Biotechnology Biomedical Engineering Computer Science Applications |
title_short |
On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds |
title_full |
On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds |
title_fullStr |
On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds |
title_full_unstemmed |
On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds |
title_sort |
On the effect of design and fabrication parameters on mechanical performance of 3D printed PLA scaffolds |
author |
Baptista, Ricardo |
author_facet |
Baptista, Ricardo Guedes, Mafalda Pereira, Manuel F. C. Maurício, António Carrelo, Henrique Cidade, Teresa |
author_role |
author |
author2 |
Guedes, Mafalda Pereira, Manuel F. C. Maurício, António Carrelo, Henrique Cidade, Teresa |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N) DCM - Departamento de Ciência dos Materiais RUN |
dc.contributor.author.fl_str_mv |
Baptista, Ricardo Guedes, Mafalda Pereira, Manuel F. C. Maurício, António Carrelo, Henrique Cidade, Teresa |
dc.subject.por.fl_str_mv |
3D printing Bone replacement Mechanical behavior Porosity Scaffolds Biotechnology Biomedical Engineering Computer Science Applications |
topic |
3D printing Bone replacement Mechanical behavior Porosity Scaffolds Biotechnology Biomedical Engineering Computer Science Applications |
description |
FCT through IDMEC under LAETA, project UIDB/50022/2020; CeFEMA contract UID/CTM/04540/2019 ; Strategic Project Pest - C/CTM/LA0025/2011; CERENA Strategic Project UIDB/04028/2020 . |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12 2020-12-01T00:00:00Z 2022-09-07T00:31:42Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/115478 |
url |
http://hdl.handle.net/10362/115478 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2405-8866 PURE: 28879831 https://doi.org/10.1016/j.bprint.2020.e00096 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799138038539878400 |