Hearing loss in children with congenital cytomegalovirus infection

Detalhes bibliográficos
Autor(a) principal: Caetano Oliveira, Gonçalo
Data de Publicação: 2023
Outros Autores: Morgado, Filipa, Santos, Mariana, Mota, Clara, Matos, Ricardo, Robles, Raquel, Fonseca, Rui
Tipo de documento: Artigo
Idioma: eng
por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.34631/sporl.2070
Resumo: Objective: To study the prevalence of hearing loss in children with congenital Cytomegalovirus infection and the influence of the type of maternal infection, symptoms and neonatal treatment with valganciclovir. Study design: Retrospective cohort Material and Methods: Data was collected through computerized processes of children with congenital Citomegalovirus, followed in Hospital de Guimarães, between 2017 and 2022. Hearing evaluation was performed between 2 months and 2 years old. The type of maternal infection and treatment with valganciclovir were assessed. Results: Twenty-two children were enrolled in this study. Global prevalence of hearing loss was 50%, greater in symptomatic children and children born to mothers with primary infection. After treatment with valganciclovir, 41.6% of children presented with hearing loss. Conclusion: The risk of hearing loss is greater in symptomatic children and children born to mothers with primary infection. A screening programme should be implemented regarding the high prevalence of hearing loss in asymptomatic children.
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spelling Hearing loss in children with congenital cytomegalovirus infectionSurdez em crianças com infeção congénita por citomegalovirusCitomegalovirusCMVhipoacusiavalganciclovirsurdez infantilrastreioCytomegalovirusCMVhearingvalganciclovirchildrenscreeningObjective: To study the prevalence of hearing loss in children with congenital Cytomegalovirus infection and the influence of the type of maternal infection, symptoms and neonatal treatment with valganciclovir. Study design: Retrospective cohort Material and Methods: Data was collected through computerized processes of children with congenital Citomegalovirus, followed in Hospital de Guimarães, between 2017 and 2022. Hearing evaluation was performed between 2 months and 2 years old. The type of maternal infection and treatment with valganciclovir were assessed. Results: Twenty-two children were enrolled in this study. Global prevalence of hearing loss was 50%, greater in symptomatic children and children born to mothers with primary infection. After treatment with valganciclovir, 41.6% of children presented with hearing loss. Conclusion: The risk of hearing loss is greater in symptomatic children and children born to mothers with primary infection. A screening programme should be implemented regarding the high prevalence of hearing loss in asymptomatic children.Objetivos: Estudar a prevalência de hipoacusia em crianças com diagnóstico de infeção congénita por Citomegalovirus e a influência do tipo de infeção materna, sintomatologia e tratamento neonatal com valganciclovir nesta doença. Desenho do estudo: Coorte retrospetivo. Material e Métodos: Dados obtidos através dos processos informatizados de crianças com diagnóstico de infeção congénita por Citomegalovirus, seguidas no Hospital de Guimarães, entre 2017 e 2022. A avaliação auditiva foi realizada entre os 2 meses e os 2 anos de idade. Foi determinado o tipo de infeção materna e se ocorreu tratamento com valganciclovir. Resultados: Foram incluídas 22 crianças no estudo. A prevalência de hipoacusia global foi de 50%, superior em crianças sintomáticas e após infeção materna primária. Após tratamento com valganciclovir, 41,6% das crianças manifestaram perda auditiva. Conclusão: As crianças cuja mãe apresentou infeção primária e as crianças sintomáticas têm maior risco de desenvolver hipoacusia. A implementação de um rastreio é fulcral tendo em conta a alta prevalência de hipoacusia em crianças assintomáticas.Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço2023-11-06info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://doi.org/10.34631/sporl.2070https://doi.org/10.34631/sporl.2070Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery; Vol. 61 No. 3 (2023): September; 293-297Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço; Vol. 61 Núm. 3 (2023): Setembro; 293-297Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço; Vol. 61 N.º 3 (2023): Setembro; 293-2972184-6499reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPengporhttps://journalsporl.com/index.php/sporl/article/view/2070https://journalsporl.com/index.php/sporl/article/view/2070/65https://journalsporl.com/index.php/sporl/article/view/2070/66Direitos de Autor (c) 2023 Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoçoinfo:eu-repo/semantics/openAccessCaetano Oliveira, GonçaloMorgado, FilipaSantos, MarianaMota, ClaraMatos, RicardoRobles, RaquelFonseca, Rui2023-11-09T12:00:36Zoai:journalsporl.com:article/2070Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:10:09.742041Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Hearing loss in children with congenital cytomegalovirus infection
Surdez em crianças com infeção congénita por citomegalovirus
title Hearing loss in children with congenital cytomegalovirus infection
spellingShingle Hearing loss in children with congenital cytomegalovirus infection
Caetano Oliveira, Gonçalo
Citomegalovirus
CMV
hipoacusia
valganciclovir
surdez infantil
rastreio
Cytomegalovirus
CMV
hearing
valganciclovir
children
screening
title_short Hearing loss in children with congenital cytomegalovirus infection
title_full Hearing loss in children with congenital cytomegalovirus infection
title_fullStr Hearing loss in children with congenital cytomegalovirus infection
title_full_unstemmed Hearing loss in children with congenital cytomegalovirus infection
title_sort Hearing loss in children with congenital cytomegalovirus infection
author Caetano Oliveira, Gonçalo
author_facet Caetano Oliveira, Gonçalo
Morgado, Filipa
Santos, Mariana
Mota, Clara
Matos, Ricardo
Robles, Raquel
Fonseca, Rui
author_role author
author2 Morgado, Filipa
Santos, Mariana
Mota, Clara
Matos, Ricardo
Robles, Raquel
Fonseca, Rui
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Caetano Oliveira, Gonçalo
Morgado, Filipa
Santos, Mariana
Mota, Clara
Matos, Ricardo
Robles, Raquel
Fonseca, Rui
dc.subject.por.fl_str_mv Citomegalovirus
CMV
hipoacusia
valganciclovir
surdez infantil
rastreio
Cytomegalovirus
CMV
hearing
valganciclovir
children
screening
topic Citomegalovirus
CMV
hipoacusia
valganciclovir
surdez infantil
rastreio
Cytomegalovirus
CMV
hearing
valganciclovir
children
screening
description Objective: To study the prevalence of hearing loss in children with congenital Cytomegalovirus infection and the influence of the type of maternal infection, symptoms and neonatal treatment with valganciclovir. Study design: Retrospective cohort Material and Methods: Data was collected through computerized processes of children with congenital Citomegalovirus, followed in Hospital de Guimarães, between 2017 and 2022. Hearing evaluation was performed between 2 months and 2 years old. The type of maternal infection and treatment with valganciclovir were assessed. Results: Twenty-two children were enrolled in this study. Global prevalence of hearing loss was 50%, greater in symptomatic children and children born to mothers with primary infection. After treatment with valganciclovir, 41.6% of children presented with hearing loss. Conclusion: The risk of hearing loss is greater in symptomatic children and children born to mothers with primary infection. A screening programme should be implemented regarding the high prevalence of hearing loss in asymptomatic children.
publishDate 2023
dc.date.none.fl_str_mv 2023-11-06
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.34631/sporl.2070
https://doi.org/10.34631/sporl.2070
url https://doi.org/10.34631/sporl.2070
dc.language.iso.fl_str_mv eng
por
language eng
por
dc.relation.none.fl_str_mv https://journalsporl.com/index.php/sporl/article/view/2070
https://journalsporl.com/index.php/sporl/article/view/2070/65
https://journalsporl.com/index.php/sporl/article/view/2070/66
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2023 Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2023 Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço
publisher.none.fl_str_mv Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço
dc.source.none.fl_str_mv Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery; Vol. 61 No. 3 (2023): September; 293-297
Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço; Vol. 61 Núm. 3 (2023): Setembro; 293-297
Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço; Vol. 61 N.º 3 (2023): Setembro; 293-297
2184-6499
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instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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