Stabilization of silver nanoparticles on polyester fabric using organo-matrices for controlled antimicrobial performance

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Ana Isabel Ferreira
Data de Publicação: 2022
Outros Autores: Shvalya, Vasyl, Cvelbar, Uroš, Silva, Renata, Marques-Oliveira, Rita, Remião, Fernando, Felgueiras, Helena Prado, Padrão, Jorge, Zille, Andrea
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/1822/76491
Resumo: Antimicrobial textiles are helpful tools to fight against multidrug-resistant pathogens and nosocomial infections. The deposition of silver nanoparticles (AgNPs) onto textiles has been studied to achieve antimicrobial properties. Yet, due to health and environmental safety concerns associated with such formulations, processing optimizations have been introduced: biocompatible materials, environmentally friendly agents, and delivery platforms that ensure a controlled release. In particular, the functionalization of polyester (PES) fabric with antimicrobial agents is a formulation in high demand in medical textiles. However, the lack of functional groups on PES fabric hinders the development of cost-effective, durable systems that allow a controlled release of antimicrobial agents. In this work, PES fabric was functionalized with AgNPs using one or two biocompatible layers of chitosan or hexamethyldisiloxane (HMDSO). The addition of organo-matrices stabilized the AgNPs onto the fabrics, protected AgNPs from further oxidation, and controlled their release. In addition, the layered samples were efficient against Staphylococcus aureus and Escherichia coli. The sample with two layers of chitosan showed the highest efficacy against S. aureus (log reduction of 2.15 ± 1.08 after 3 h of contact). Against E. coli, the sample with two layers of chitosan showed the best properties. Chitosan allowed to control the antimicrobial activity of AgNPs, avoid the complete loss of AgNPs after washings and act in synergy with AgNPs. After 3 h of incubation, this sample presented a log reduction of 4.81, and 7.27 of log reduction after 5 h of incubation. The antimicrobial results after washing showed a log reduction of 3.47 and 4.88 after 3 h and 5 h of contact, respectively. Furthermore, the sample with a final layer of HMDSO also presented a controlled antimicrobial effect. The antimicrobial effect was slower than the sample with just an initial layer of HMDSO, with a log reduction of 4.40 after 3 h of incubation (instead of 7.22) and 7.27 after 5 h. The biocompatibility of the composites was confirmed through the evaluation of their cytotoxicity towards HaCaT cells (cells viability > 96% in all samples). Therefore, the produced nanocomposites could have interesting applications in medical textiles once they present controlled antimicrobial properties, high biocompatibility and avoid the complete release of AgNPs to the environment.
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spelling Stabilization of silver nanoparticles on polyester fabric using organo-matrices for controlled antimicrobial performanceSilver nanoparticlesChitosanSpray depositionAntimicrobial textilesHexamethyldisiloxaneEngenharia e Tecnologia::Engenharia dos MateriaisScience & TechnologyAntimicrobial textiles are helpful tools to fight against multidrug-resistant pathogens and nosocomial infections. The deposition of silver nanoparticles (AgNPs) onto textiles has been studied to achieve antimicrobial properties. Yet, due to health and environmental safety concerns associated with such formulations, processing optimizations have been introduced: biocompatible materials, environmentally friendly agents, and delivery platforms that ensure a controlled release. In particular, the functionalization of polyester (PES) fabric with antimicrobial agents is a formulation in high demand in medical textiles. However, the lack of functional groups on PES fabric hinders the development of cost-effective, durable systems that allow a controlled release of antimicrobial agents. In this work, PES fabric was functionalized with AgNPs using one or two biocompatible layers of chitosan or hexamethyldisiloxane (HMDSO). The addition of organo-matrices stabilized the AgNPs onto the fabrics, protected AgNPs from further oxidation, and controlled their release. In addition, the layered samples were efficient against Staphylococcus aureus and Escherichia coli. The sample with two layers of chitosan showed the highest efficacy against S. aureus (log reduction of 2.15 ± 1.08 after 3 h of contact). Against E. coli, the sample with two layers of chitosan showed the best properties. Chitosan allowed to control the antimicrobial activity of AgNPs, avoid the complete loss of AgNPs after washings and act in synergy with AgNPs. After 3 h of incubation, this sample presented a log reduction of 4.81, and 7.27 of log reduction after 5 h of incubation. The antimicrobial results after washing showed a log reduction of 3.47 and 4.88 after 3 h and 5 h of contact, respectively. Furthermore, the sample with a final layer of HMDSO also presented a controlled antimicrobial effect. The antimicrobial effect was slower than the sample with just an initial layer of HMDSO, with a log reduction of 4.40 after 3 h of incubation (instead of 7.22) and 7.27 after 5 h. The biocompatibility of the composites was confirmed through the evaluation of their cytotoxicity towards HaCaT cells (cells viability > 96% in all samples). Therefore, the produced nanocomposites could have interesting applications in medical textiles once they present controlled antimicrobial properties, high biocompatibility and avoid the complete release of AgNPs to the environment.This research was funded by the projects PLASMAMED-PTDC/CTM-TEX/28295/2017 and MEDCOR-PTDC/CTM-TEX/1213/2020, the project UID/CTM/00264/2021 of 2C2T under the COMPETE and FCT/MCTES (PIDDAC) co-financed by FEDER through the PT2020 program.MDPIUniversidade do MinhoRibeiro, Ana Isabel FerreiraShvalya, VasylCvelbar, UrošSilva, RenataMarques-Oliveira, RitaRemião, FernandoFelgueiras, Helena PradoPadrão, JorgeZille, Andrea20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/76491eng2073-436010.3390/polym14061138https://www.mdpi.com/2073-4360/14/6/1138info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:03:38ZPortal AgregadorONG
dc.title.none.fl_str_mv Stabilization of silver nanoparticles on polyester fabric using organo-matrices for controlled antimicrobial performance
title Stabilization of silver nanoparticles on polyester fabric using organo-matrices for controlled antimicrobial performance
spellingShingle Stabilization of silver nanoparticles on polyester fabric using organo-matrices for controlled antimicrobial performance
Ribeiro, Ana Isabel Ferreira
Silver nanoparticles
Chitosan
Spray deposition
Antimicrobial textiles
Hexamethyldisiloxane
Engenharia e Tecnologia::Engenharia dos Materiais
Science & Technology
title_short Stabilization of silver nanoparticles on polyester fabric using organo-matrices for controlled antimicrobial performance
title_full Stabilization of silver nanoparticles on polyester fabric using organo-matrices for controlled antimicrobial performance
title_fullStr Stabilization of silver nanoparticles on polyester fabric using organo-matrices for controlled antimicrobial performance
title_full_unstemmed Stabilization of silver nanoparticles on polyester fabric using organo-matrices for controlled antimicrobial performance
title_sort Stabilization of silver nanoparticles on polyester fabric using organo-matrices for controlled antimicrobial performance
author Ribeiro, Ana Isabel Ferreira
author_facet Ribeiro, Ana Isabel Ferreira
Shvalya, Vasyl
Cvelbar, Uroš
Silva, Renata
Marques-Oliveira, Rita
Remião, Fernando
Felgueiras, Helena Prado
Padrão, Jorge
Zille, Andrea
author_role author
author2 Shvalya, Vasyl
Cvelbar, Uroš
Silva, Renata
Marques-Oliveira, Rita
Remião, Fernando
Felgueiras, Helena Prado
Padrão, Jorge
Zille, Andrea
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Ribeiro, Ana Isabel Ferreira
Shvalya, Vasyl
Cvelbar, Uroš
Silva, Renata
Marques-Oliveira, Rita
Remião, Fernando
Felgueiras, Helena Prado
Padrão, Jorge
Zille, Andrea
dc.subject.por.fl_str_mv Silver nanoparticles
Chitosan
Spray deposition
Antimicrobial textiles
Hexamethyldisiloxane
Engenharia e Tecnologia::Engenharia dos Materiais
Science & Technology
topic Silver nanoparticles
Chitosan
Spray deposition
Antimicrobial textiles
Hexamethyldisiloxane
Engenharia e Tecnologia::Engenharia dos Materiais
Science & Technology
description Antimicrobial textiles are helpful tools to fight against multidrug-resistant pathogens and nosocomial infections. The deposition of silver nanoparticles (AgNPs) onto textiles has been studied to achieve antimicrobial properties. Yet, due to health and environmental safety concerns associated with such formulations, processing optimizations have been introduced: biocompatible materials, environmentally friendly agents, and delivery platforms that ensure a controlled release. In particular, the functionalization of polyester (PES) fabric with antimicrobial agents is a formulation in high demand in medical textiles. However, the lack of functional groups on PES fabric hinders the development of cost-effective, durable systems that allow a controlled release of antimicrobial agents. In this work, PES fabric was functionalized with AgNPs using one or two biocompatible layers of chitosan or hexamethyldisiloxane (HMDSO). The addition of organo-matrices stabilized the AgNPs onto the fabrics, protected AgNPs from further oxidation, and controlled their release. In addition, the layered samples were efficient against Staphylococcus aureus and Escherichia coli. The sample with two layers of chitosan showed the highest efficacy against S. aureus (log reduction of 2.15 ± 1.08 after 3 h of contact). Against E. coli, the sample with two layers of chitosan showed the best properties. Chitosan allowed to control the antimicrobial activity of AgNPs, avoid the complete loss of AgNPs after washings and act in synergy with AgNPs. After 3 h of incubation, this sample presented a log reduction of 4.81, and 7.27 of log reduction after 5 h of incubation. The antimicrobial results after washing showed a log reduction of 3.47 and 4.88 after 3 h and 5 h of contact, respectively. Furthermore, the sample with a final layer of HMDSO also presented a controlled antimicrobial effect. The antimicrobial effect was slower than the sample with just an initial layer of HMDSO, with a log reduction of 4.40 after 3 h of incubation (instead of 7.22) and 7.27 after 5 h. The biocompatibility of the composites was confirmed through the evaluation of their cytotoxicity towards HaCaT cells (cells viability > 96% in all samples). Therefore, the produced nanocomposites could have interesting applications in medical textiles once they present controlled antimicrobial properties, high biocompatibility and avoid the complete release of AgNPs to the environment.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/76491
url https://hdl.handle.net/1822/76491
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2073-4360
10.3390/polym14061138
https://www.mdpi.com/2073-4360/14/6/1138
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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