The atrial fibrillation burden during the blanking period is predictive of time to recurrence after catheter ablation
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/145497 |
Resumo: | Objective: This study aimed to assess whether atrial fibrillation (AF) occurrence or its corresponding daily mean burden (in minutes/day) during the mid to late blanking period after pulmonary vein isolation (PVI), predicts AF recurrence. Methods: Analysis of consecutive first PVI ablation patients undergoing prolonged electrocardiogram (ECG) monitoring during the second and third months after PVI. The clinical variables, total AF burden, and their relationship with time to recurrence were studied. Results: 477 patients with a mean age of 56.9 (SD = 12.3) years (63.7 % male; 71.7 % paroxysmal AF), from which 317 (66.5 %) had an external event recorder between 30 and 90 days after ablation. Median follow-up of 16.0 (P 25:12.0: P 75:33.0) months, 177 (37 %) patients had an AF recurrence, with 106 (22.2 %) having the first episode after 12 months of follow-up. In the group of patients with an event recorder, 80 (25.2 %) had AF documented during the blanking period. Multivariable analysis showed that AF during the blanking period was associated with a 4-fold higher risk of recurrence (HR: 3.98; 95 %CI: 2.95–5.37), and, compared to patients in sinus rhythm, those with an AF burden ≥ 23 min/day had an approximately 7-fold higher risk of recurrence (HR estimate: 6.79; 95 %CI: 4.56–10.10). Conclusions: The probability of experiencing AF recurrence can be predicted by atrial tachyarrhythmia episodes during the second and third months after PVI. Atrial arrhythmias burden > 23 min/day has a high predictive ability for recurrence. |
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7160 |
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The atrial fibrillation burden during the blanking period is predictive of time to recurrence after catheter ablationArrhythmia burdenArrhythmia recurrenceAtrial fibrillationBlanking periodCatheter ablationPulmonary vein isolationCardiology and Cardiovascular MedicineObjective: This study aimed to assess whether atrial fibrillation (AF) occurrence or its corresponding daily mean burden (in minutes/day) during the mid to late blanking period after pulmonary vein isolation (PVI), predicts AF recurrence. Methods: Analysis of consecutive first PVI ablation patients undergoing prolonged electrocardiogram (ECG) monitoring during the second and third months after PVI. The clinical variables, total AF burden, and their relationship with time to recurrence were studied. Results: 477 patients with a mean age of 56.9 (SD = 12.3) years (63.7 % male; 71.7 % paroxysmal AF), from which 317 (66.5 %) had an external event recorder between 30 and 90 days after ablation. Median follow-up of 16.0 (P 25:12.0: P 75:33.0) months, 177 (37 %) patients had an AF recurrence, with 106 (22.2 %) having the first episode after 12 months of follow-up. In the group of patients with an event recorder, 80 (25.2 %) had AF documented during the blanking period. Multivariable analysis showed that AF during the blanking period was associated with a 4-fold higher risk of recurrence (HR: 3.98; 95 %CI: 2.95–5.37), and, compared to patients in sinus rhythm, those with an AF burden ≥ 23 min/day had an approximately 7-fold higher risk of recurrence (HR estimate: 6.79; 95 %CI: 4.56–10.10). Conclusions: The probability of experiencing AF recurrence can be predicted by atrial tachyarrhythmia episodes during the second and third months after PVI. Atrial arrhythmias burden > 23 min/day has a high predictive ability for recurrence.Comprehensive Health Research Centre (CHRC) - pólo NMSNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNSilva Cunha, PedroPortugal, GuilhermeLaranjo, SérgioAlves, MartaLuísa Papoila, AnaValente, BrunoSofia Delgado, AnaLousinha, AnaPaulo, MargaridaBrás, ManuelGuerra, CátiaCruz Ferreira, RuiMartins Oliveira, Mário2022-11-14T22:09:56Z2022-122022-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/145497eng2352-9067PURE: 47607868https://doi.org/10.1016/j.ijcha.2022.101138info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:25:55Zoai:run.unl.pt:10362/145497Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:52:06.586678Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The atrial fibrillation burden during the blanking period is predictive of time to recurrence after catheter ablation |
title |
The atrial fibrillation burden during the blanking period is predictive of time to recurrence after catheter ablation |
spellingShingle |
The atrial fibrillation burden during the blanking period is predictive of time to recurrence after catheter ablation Silva Cunha, Pedro Arrhythmia burden Arrhythmia recurrence Atrial fibrillation Blanking period Catheter ablation Pulmonary vein isolation Cardiology and Cardiovascular Medicine |
title_short |
The atrial fibrillation burden during the blanking period is predictive of time to recurrence after catheter ablation |
title_full |
The atrial fibrillation burden during the blanking period is predictive of time to recurrence after catheter ablation |
title_fullStr |
The atrial fibrillation burden during the blanking period is predictive of time to recurrence after catheter ablation |
title_full_unstemmed |
The atrial fibrillation burden during the blanking period is predictive of time to recurrence after catheter ablation |
title_sort |
The atrial fibrillation burden during the blanking period is predictive of time to recurrence after catheter ablation |
author |
Silva Cunha, Pedro |
author_facet |
Silva Cunha, Pedro Portugal, Guilherme Laranjo, Sérgio Alves, Marta Luísa Papoila, Ana Valente, Bruno Sofia Delgado, Ana Lousinha, Ana Paulo, Margarida Brás, Manuel Guerra, Cátia Cruz Ferreira, Rui Martins Oliveira, Mário |
author_role |
author |
author2 |
Portugal, Guilherme Laranjo, Sérgio Alves, Marta Luísa Papoila, Ana Valente, Bruno Sofia Delgado, Ana Lousinha, Ana Paulo, Margarida Brás, Manuel Guerra, Cátia Cruz Ferreira, Rui Martins Oliveira, Mário |
author2_role |
author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Comprehensive Health Research Centre (CHRC) - pólo NMS NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) RUN |
dc.contributor.author.fl_str_mv |
Silva Cunha, Pedro Portugal, Guilherme Laranjo, Sérgio Alves, Marta Luísa Papoila, Ana Valente, Bruno Sofia Delgado, Ana Lousinha, Ana Paulo, Margarida Brás, Manuel Guerra, Cátia Cruz Ferreira, Rui Martins Oliveira, Mário |
dc.subject.por.fl_str_mv |
Arrhythmia burden Arrhythmia recurrence Atrial fibrillation Blanking period Catheter ablation Pulmonary vein isolation Cardiology and Cardiovascular Medicine |
topic |
Arrhythmia burden Arrhythmia recurrence Atrial fibrillation Blanking period Catheter ablation Pulmonary vein isolation Cardiology and Cardiovascular Medicine |
description |
Objective: This study aimed to assess whether atrial fibrillation (AF) occurrence or its corresponding daily mean burden (in minutes/day) during the mid to late blanking period after pulmonary vein isolation (PVI), predicts AF recurrence. Methods: Analysis of consecutive first PVI ablation patients undergoing prolonged electrocardiogram (ECG) monitoring during the second and third months after PVI. The clinical variables, total AF burden, and their relationship with time to recurrence were studied. Results: 477 patients with a mean age of 56.9 (SD = 12.3) years (63.7 % male; 71.7 % paroxysmal AF), from which 317 (66.5 %) had an external event recorder between 30 and 90 days after ablation. Median follow-up of 16.0 (P 25:12.0: P 75:33.0) months, 177 (37 %) patients had an AF recurrence, with 106 (22.2 %) having the first episode after 12 months of follow-up. In the group of patients with an event recorder, 80 (25.2 %) had AF documented during the blanking period. Multivariable analysis showed that AF during the blanking period was associated with a 4-fold higher risk of recurrence (HR: 3.98; 95 %CI: 2.95–5.37), and, compared to patients in sinus rhythm, those with an AF burden ≥ 23 min/day had an approximately 7-fold higher risk of recurrence (HR estimate: 6.79; 95 %CI: 4.56–10.10). Conclusions: The probability of experiencing AF recurrence can be predicted by atrial tachyarrhythmia episodes during the second and third months after PVI. Atrial arrhythmias burden > 23 min/day has a high predictive ability for recurrence. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-11-14T22:09:56Z 2022-12 2022-12-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/145497 |
url |
http://hdl.handle.net/10362/145497 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2352-9067 PURE: 47607868 https://doi.org/10.1016/j.ijcha.2022.101138 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799138112936345600 |