Taraxacum spp. in vitro and in vivo anticancer activity – a review

Detalhes bibliográficos
Autor(a) principal: Oliveira, Ana Isabel
Data de Publicação: 2022
Outros Autores: Pinho, Cláudia, Quintela Vieira, Ana Filipa, Silva, Regina, Cruz, Agostinho
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.22/21192
Resumo: Cancer is one of the major causes of death universally. Conventional chemotherapeutic agents are associated with severe side effects which limit their general acceptability and leads to a search for alternative efficient and safe options. Plants have been used for centuries as medicinal agents in the treatment of several diseases, including cancer. Dandelion is a plant of the genus Taraxacum and a member of the Asteraceae family with worldwide distribution. It has been used in traditional medicine for the treatment of various disorders, such as gastrointestinal and kidney diseases, dyspepsia, Diabetes mellitus, pneumonia and cancer. The present review aims to provide a comprehensive summary of the main biologically active compounds of dandelion, gathering and describing the information about its anticancer activity. Several in vitro and in vivo studies have demonstrated the cytotoxic ability of Taraxacum species, which can be possibly explained by the complexity and diversity of its phytochemical profile. Therefore, dandelion may have the potential to become an effective chemotherapeutic agent despite the need for further studies.
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spelling Taraxacum spp. in vitro and in vivo anticancer activity – a reviewTaraxacumDandelionCancer therapyPhytochemicalsCancer is one of the major causes of death universally. Conventional chemotherapeutic agents are associated with severe side effects which limit their general acceptability and leads to a search for alternative efficient and safe options. Plants have been used for centuries as medicinal agents in the treatment of several diseases, including cancer. Dandelion is a plant of the genus Taraxacum and a member of the Asteraceae family with worldwide distribution. It has been used in traditional medicine for the treatment of various disorders, such as gastrointestinal and kidney diseases, dyspepsia, Diabetes mellitus, pneumonia and cancer. The present review aims to provide a comprehensive summary of the main biologically active compounds of dandelion, gathering and describing the information about its anticancer activity. Several in vitro and in vivo studies have demonstrated the cytotoxic ability of Taraxacum species, which can be possibly explained by the complexity and diversity of its phytochemical profile. Therefore, dandelion may have the potential to become an effective chemotherapeutic agent despite the need for further studies.ElsevierRepositório Científico do Instituto Politécnico do PortoOliveira, Ana IsabelPinho, CláudiaQuintela Vieira, Ana FilipaSilva, ReginaCruz, Agostinho2022-12-13T18:12:25Z2022-11-082022-11-08T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/21192engOliveira, A. I., Pinho, C., Vieira, F. Q., Silva, R., & Cruz, A. (2022). Taraxacum spp. In vitro and in vivo anticancer activity – A review. Journal of Herbal Medicine, 36, 100612. https://doi.org/10.1016/j.hermed.2022.1006122210-803310.1016/j.hermed.2022.1006122210-8041metadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-13T01:47:47Zoai:recipp.ipp.pt:10400.22/21192Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:41:16.221936Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Taraxacum spp. in vitro and in vivo anticancer activity – a review
title Taraxacum spp. in vitro and in vivo anticancer activity – a review
spellingShingle Taraxacum spp. in vitro and in vivo anticancer activity – a review
Oliveira, Ana Isabel
Taraxacum
Dandelion
Cancer therapy
Phytochemicals
title_short Taraxacum spp. in vitro and in vivo anticancer activity – a review
title_full Taraxacum spp. in vitro and in vivo anticancer activity – a review
title_fullStr Taraxacum spp. in vitro and in vivo anticancer activity – a review
title_full_unstemmed Taraxacum spp. in vitro and in vivo anticancer activity – a review
title_sort Taraxacum spp. in vitro and in vivo anticancer activity – a review
author Oliveira, Ana Isabel
author_facet Oliveira, Ana Isabel
Pinho, Cláudia
Quintela Vieira, Ana Filipa
Silva, Regina
Cruz, Agostinho
author_role author
author2 Pinho, Cláudia
Quintela Vieira, Ana Filipa
Silva, Regina
Cruz, Agostinho
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico do Porto
dc.contributor.author.fl_str_mv Oliveira, Ana Isabel
Pinho, Cláudia
Quintela Vieira, Ana Filipa
Silva, Regina
Cruz, Agostinho
dc.subject.por.fl_str_mv Taraxacum
Dandelion
Cancer therapy
Phytochemicals
topic Taraxacum
Dandelion
Cancer therapy
Phytochemicals
description Cancer is one of the major causes of death universally. Conventional chemotherapeutic agents are associated with severe side effects which limit their general acceptability and leads to a search for alternative efficient and safe options. Plants have been used for centuries as medicinal agents in the treatment of several diseases, including cancer. Dandelion is a plant of the genus Taraxacum and a member of the Asteraceae family with worldwide distribution. It has been used in traditional medicine for the treatment of various disorders, such as gastrointestinal and kidney diseases, dyspepsia, Diabetes mellitus, pneumonia and cancer. The present review aims to provide a comprehensive summary of the main biologically active compounds of dandelion, gathering and describing the information about its anticancer activity. Several in vitro and in vivo studies have demonstrated the cytotoxic ability of Taraxacum species, which can be possibly explained by the complexity and diversity of its phytochemical profile. Therefore, dandelion may have the potential to become an effective chemotherapeutic agent despite the need for further studies.
publishDate 2022
dc.date.none.fl_str_mv 2022-12-13T18:12:25Z
2022-11-08
2022-11-08T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/21192
url http://hdl.handle.net/10400.22/21192
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Oliveira, A. I., Pinho, C., Vieira, F. Q., Silva, R., & Cruz, A. (2022). Taraxacum spp. In vitro and in vivo anticancer activity – A review. Journal of Herbal Medicine, 36, 100612. https://doi.org/10.1016/j.hermed.2022.100612
2210-8033
10.1016/j.hermed.2022.100612
2210-8041
dc.rights.driver.fl_str_mv metadata only access
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rights_invalid_str_mv metadata only access
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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