Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood
Autor(a) principal: | |
---|---|
Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.1/19508 |
Resumo: | Background This study was aimed to examine the relationship between muscular fitness indicators in childhood and areal bone mineral density (aBMD) in adulthood and to verify whether the relationship is mediated by performance on muscular fitness indicators in adulthood. Methods A sample of 138 healthy adults (69 males; 22.3 years) were followed after a previous assessment at the age of 7–10 years. Stature, body mass and muscular fitness indicators (handgrip strength, standing long jump and sit-ups tests) were assessed in childhood and adulthood. Additionally, total body, upper limbs, lower limbs, right femoral neck and lumbar spine aBMD was assessed in adulthood using dual X-ray absorptiometry. Analysis included descriptive statistics; t-test or Mann-Whitney U-test for comparison between males and females, multiple linear regression for the prediction aBMD from muscular fitness indicators in childhood, mediation analysis of the respective muscular fitness indicators in adulthood and the relationship between muscular fitness indicators in childhood and aBMD. Results Males were stronger compared to females regarding muscular fitness indicators in childhood and adulthood, and presented higher mean values for aBMD in adulthood, except for lumbar spine (p<0.05). Regression analysis revealed that some muscular fitness indicators in childhood showed significant positive relationship with bone health indicators in adulthood, such as: handgrip strength and total body aBMD (β=0.005; R2=0.35; p=0.040) and upper limbs aBMD (β=0.005; R2=0.55; p=0.019); and sit-ups test was a significant predictors of lumbar spine BMD (β=0.003; R2=0.06; p=0.039). Mediation analysis pointed out the following: adulthood handgrip strength mediated relationships between childhood handgrip strength and total aBMD (indirect effect (IE)=0.0025; 95%CI=0.0005– 0.0048), and upper limbs aBMD (IE=0.0040; 95%CI=0.0017–0.0069). Conclusions Muscular fitness indicators in childhood showed significant relationship with bone health indicators in adulthood and the sit-ups test in childhood had direct effect on lumbar spine aBMD in adulthood. Adulthoodhandgrip strength mediated the relationship between childhood handgrip strength and total body and upper limb aBMD, pointing out that muscular fitness in childhood may be a aBMD determinant in adulthood, especially when higher muscle fitness performance is maintained in adulthood. |
id |
RCAP_4fe8d6c906ad0ad0519f1be5a4cde9fc |
---|---|
oai_identifier_str |
oai:sapientia.ualg.pt:10400.1/19508 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthoodPhysical fitnessMuscle strengthBone healthGrowthBackground This study was aimed to examine the relationship between muscular fitness indicators in childhood and areal bone mineral density (aBMD) in adulthood and to verify whether the relationship is mediated by performance on muscular fitness indicators in adulthood. Methods A sample of 138 healthy adults (69 males; 22.3 years) were followed after a previous assessment at the age of 7–10 years. Stature, body mass and muscular fitness indicators (handgrip strength, standing long jump and sit-ups tests) were assessed in childhood and adulthood. Additionally, total body, upper limbs, lower limbs, right femoral neck and lumbar spine aBMD was assessed in adulthood using dual X-ray absorptiometry. Analysis included descriptive statistics; t-test or Mann-Whitney U-test for comparison between males and females, multiple linear regression for the prediction aBMD from muscular fitness indicators in childhood, mediation analysis of the respective muscular fitness indicators in adulthood and the relationship between muscular fitness indicators in childhood and aBMD. Results Males were stronger compared to females regarding muscular fitness indicators in childhood and adulthood, and presented higher mean values for aBMD in adulthood, except for lumbar spine (p<0.05). Regression analysis revealed that some muscular fitness indicators in childhood showed significant positive relationship with bone health indicators in adulthood, such as: handgrip strength and total body aBMD (β=0.005; R2=0.35; p=0.040) and upper limbs aBMD (β=0.005; R2=0.55; p=0.019); and sit-ups test was a significant predictors of lumbar spine BMD (β=0.003; R2=0.06; p=0.039). Mediation analysis pointed out the following: adulthood handgrip strength mediated relationships between childhood handgrip strength and total aBMD (indirect effect (IE)=0.0025; 95%CI=0.0005– 0.0048), and upper limbs aBMD (IE=0.0040; 95%CI=0.0017–0.0069). Conclusions Muscular fitness indicators in childhood showed significant relationship with bone health indicators in adulthood and the sit-ups test in childhood had direct effect on lumbar spine aBMD in adulthood. Adulthoodhandgrip strength mediated the relationship between childhood handgrip strength and total body and upper limb aBMD, pointing out that muscular fitness in childhood may be a aBMD determinant in adulthood, especially when higher muscle fitness performance is maintained in adulthood.BMCSapientiaBarbosa, Cynthia C. L.da Costa, Julio C.Romanzini, Catiana L. P.Batista, Mariana B.Blasquez-Shigaki, GabrielaFernandes, Rômulo A.Martinho, Diogo V.Oliveira, TomásRibeiro, Luís PedroCoelho-e-Silva, Manuel J.Ronque, Enio R. V.2023-05-02T13:18:59Z2023-04-042023-05-01T03:10:31Z2023-04-04T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/19508engenBMC Public Health. 2023 Apr 04;23(1):648https://doi.org/10.1186/s12889-023-15545-7info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-24T10:31:59Zoai:sapientia.ualg.pt:10400.1/19508Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:09:08.100069Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood |
title |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood |
spellingShingle |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood Barbosa, Cynthia C. L. Physical fitness Muscle strength Bone health Growth |
title_short |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood |
title_full |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood |
title_fullStr |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood |
title_full_unstemmed |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood |
title_sort |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood |
author |
Barbosa, Cynthia C. L. |
author_facet |
Barbosa, Cynthia C. L. da Costa, Julio C. Romanzini, Catiana L. P. Batista, Mariana B. Blasquez-Shigaki, Gabriela Fernandes, Rômulo A. Martinho, Diogo V. Oliveira, Tomás Ribeiro, Luís Pedro Coelho-e-Silva, Manuel J. Ronque, Enio R. V. |
author_role |
author |
author2 |
da Costa, Julio C. Romanzini, Catiana L. P. Batista, Mariana B. Blasquez-Shigaki, Gabriela Fernandes, Rômulo A. Martinho, Diogo V. Oliveira, Tomás Ribeiro, Luís Pedro Coelho-e-Silva, Manuel J. Ronque, Enio R. V. |
author2_role |
author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Sapientia |
dc.contributor.author.fl_str_mv |
Barbosa, Cynthia C. L. da Costa, Julio C. Romanzini, Catiana L. P. Batista, Mariana B. Blasquez-Shigaki, Gabriela Fernandes, Rômulo A. Martinho, Diogo V. Oliveira, Tomás Ribeiro, Luís Pedro Coelho-e-Silva, Manuel J. Ronque, Enio R. V. |
dc.subject.por.fl_str_mv |
Physical fitness Muscle strength Bone health Growth |
topic |
Physical fitness Muscle strength Bone health Growth |
description |
Background This study was aimed to examine the relationship between muscular fitness indicators in childhood and areal bone mineral density (aBMD) in adulthood and to verify whether the relationship is mediated by performance on muscular fitness indicators in adulthood. Methods A sample of 138 healthy adults (69 males; 22.3 years) were followed after a previous assessment at the age of 7–10 years. Stature, body mass and muscular fitness indicators (handgrip strength, standing long jump and sit-ups tests) were assessed in childhood and adulthood. Additionally, total body, upper limbs, lower limbs, right femoral neck and lumbar spine aBMD was assessed in adulthood using dual X-ray absorptiometry. Analysis included descriptive statistics; t-test or Mann-Whitney U-test for comparison between males and females, multiple linear regression for the prediction aBMD from muscular fitness indicators in childhood, mediation analysis of the respective muscular fitness indicators in adulthood and the relationship between muscular fitness indicators in childhood and aBMD. Results Males were stronger compared to females regarding muscular fitness indicators in childhood and adulthood, and presented higher mean values for aBMD in adulthood, except for lumbar spine (p<0.05). Regression analysis revealed that some muscular fitness indicators in childhood showed significant positive relationship with bone health indicators in adulthood, such as: handgrip strength and total body aBMD (β=0.005; R2=0.35; p=0.040) and upper limbs aBMD (β=0.005; R2=0.55; p=0.019); and sit-ups test was a significant predictors of lumbar spine BMD (β=0.003; R2=0.06; p=0.039). Mediation analysis pointed out the following: adulthood handgrip strength mediated relationships between childhood handgrip strength and total aBMD (indirect effect (IE)=0.0025; 95%CI=0.0005– 0.0048), and upper limbs aBMD (IE=0.0040; 95%CI=0.0017–0.0069). Conclusions Muscular fitness indicators in childhood showed significant relationship with bone health indicators in adulthood and the sit-ups test in childhood had direct effect on lumbar spine aBMD in adulthood. Adulthoodhandgrip strength mediated the relationship between childhood handgrip strength and total body and upper limb aBMD, pointing out that muscular fitness in childhood may be a aBMD determinant in adulthood, especially when higher muscle fitness performance is maintained in adulthood. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-05-02T13:18:59Z 2023-04-04 2023-05-01T03:10:31Z 2023-04-04T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.1/19508 |
url |
http://hdl.handle.net/10400.1/19508 |
dc.language.iso.fl_str_mv |
eng en |
language |
eng |
language_invalid_str_mv |
en |
dc.relation.none.fl_str_mv |
BMC Public Health. 2023 Apr 04;23(1):648 https://doi.org/10.1186/s12889-023-15545-7 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
BMC |
publisher.none.fl_str_mv |
BMC |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799133338424836096 |