Type 1 Diabetes Mellitus presenting as neurodevelopmental impairment

Detalhes bibliográficos
Autor(a) principal: Alves, Marta Faria
Data de Publicação: 2018
Outros Autores: Costeira, Mónica, Ferreira, Joana da Silva, Soares, Susana, Magalhães, Catarina, Meireles, Carla
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25753/BirthGrowthMJ.v27.i2.10719
Resumo: Introduction: Type 1 Diabetes Mellitus is one of the most prevalent chronic diseases in childhood and adolescence. Disease presentation is diverse, depending on the duration of symptoms and the age of onset. Case report: A 30-month-old child was referred to the Paediatric Outpatient Clinic for loss of cognitive and behavioural skills and stagnation of motor abilities occurring in the last six months, weight loss and polydipsia during the previous month. The child was diagnosed with inaugural type 1 Diabetes Mellitus without acidosis. Management of the disease, through glycaemic control with insulin therapy was associated with progressive improvement of the child’s neurodevelopment. Discussion/Conclusion: This case illustrates an unusual presentation of type 1 Diabetes. The mechanisms underlying acute neurological changes associated with type 1 Diabetes are not yet completely clarified. An efficient glycaemic control benefits an adequate neurodevelopment of children with Diabetes.
id RCAP_54a36ed13105426da62de92893867bba
oai_identifier_str oai:ojs.revistas.rcaap.pt:article/10719
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Type 1 Diabetes Mellitus presenting as neurodevelopmental impairmentDiabetes Mellitus Tipo 1 apresentando-se como perturbação do neurodesenvolvimentoCase ReportsIntroduction: Type 1 Diabetes Mellitus is one of the most prevalent chronic diseases in childhood and adolescence. Disease presentation is diverse, depending on the duration of symptoms and the age of onset. Case report: A 30-month-old child was referred to the Paediatric Outpatient Clinic for loss of cognitive and behavioural skills and stagnation of motor abilities occurring in the last six months, weight loss and polydipsia during the previous month. The child was diagnosed with inaugural type 1 Diabetes Mellitus without acidosis. Management of the disease, through glycaemic control with insulin therapy was associated with progressive improvement of the child’s neurodevelopment. Discussion/Conclusion: This case illustrates an unusual presentation of type 1 Diabetes. The mechanisms underlying acute neurological changes associated with type 1 Diabetes are not yet completely clarified. An efficient glycaemic control benefits an adequate neurodevelopment of children with Diabetes.Introdução: A Diabetes Mellitus tipo 1 é uma das doenças crónicas mais prevalentes na infância e adolescência. A apresentação da doença é variável, dependendo da duração dos sintomas e da idade da criança. Caso Clínico: Os autores descrevem o caso de uma criança de 30 meses avaliada em consulta de Pediatria por perda de competências cognitivo-comportamentais e estagnação das aquisições motoras, tendo sido diagnosticada uma Diabetes Mellitus tipo 1 inaugural, sem acidose. Após a melhoria do controlo glicémico com a insulinoterapia, verificou-se uma normalização progressiva do neurodesenvolvimento da criança. Discussão/ Conclusão: Este caso ilustra uma apresentação incomum da Diabetes Mellitus tipo 1. A fisiopatologia das alterações neurológicas agudas associadas à Diabetes Mellitus tipo 1 ainda não está totalmente esclarecida. Um controlo glicémico eficaz é benéfico para o adequado neurodesenvolvimento das crianças com Diabetes.Centro Hospitalar Universitário do Porto2018-07-13T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25753/BirthGrowthMJ.v27.i2.10719eng2183-9417Alves, Marta FariaCosteira, MónicaFerreira, Joana da SilvaSoares, SusanaMagalhães, CatarinaMeireles, Carlainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-21T14:55:21Zoai:ojs.revistas.rcaap.pt:article/10719Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:56:21.928830Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Type 1 Diabetes Mellitus presenting as neurodevelopmental impairment
Diabetes Mellitus Tipo 1 apresentando-se como perturbação do neurodesenvolvimento
title Type 1 Diabetes Mellitus presenting as neurodevelopmental impairment
spellingShingle Type 1 Diabetes Mellitus presenting as neurodevelopmental impairment
Alves, Marta Faria
Case Reports
title_short Type 1 Diabetes Mellitus presenting as neurodevelopmental impairment
title_full Type 1 Diabetes Mellitus presenting as neurodevelopmental impairment
title_fullStr Type 1 Diabetes Mellitus presenting as neurodevelopmental impairment
title_full_unstemmed Type 1 Diabetes Mellitus presenting as neurodevelopmental impairment
title_sort Type 1 Diabetes Mellitus presenting as neurodevelopmental impairment
author Alves, Marta Faria
author_facet Alves, Marta Faria
Costeira, Mónica
Ferreira, Joana da Silva
Soares, Susana
Magalhães, Catarina
Meireles, Carla
author_role author
author2 Costeira, Mónica
Ferreira, Joana da Silva
Soares, Susana
Magalhães, Catarina
Meireles, Carla
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Alves, Marta Faria
Costeira, Mónica
Ferreira, Joana da Silva
Soares, Susana
Magalhães, Catarina
Meireles, Carla
dc.subject.por.fl_str_mv Case Reports
topic Case Reports
description Introduction: Type 1 Diabetes Mellitus is one of the most prevalent chronic diseases in childhood and adolescence. Disease presentation is diverse, depending on the duration of symptoms and the age of onset. Case report: A 30-month-old child was referred to the Paediatric Outpatient Clinic for loss of cognitive and behavioural skills and stagnation of motor abilities occurring in the last six months, weight loss and polydipsia during the previous month. The child was diagnosed with inaugural type 1 Diabetes Mellitus without acidosis. Management of the disease, through glycaemic control with insulin therapy was associated with progressive improvement of the child’s neurodevelopment. Discussion/Conclusion: This case illustrates an unusual presentation of type 1 Diabetes. The mechanisms underlying acute neurological changes associated with type 1 Diabetes are not yet completely clarified. An efficient glycaemic control benefits an adequate neurodevelopment of children with Diabetes.
publishDate 2018
dc.date.none.fl_str_mv 2018-07-13T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.25753/BirthGrowthMJ.v27.i2.10719
url https://doi.org/10.25753/BirthGrowthMJ.v27.i2.10719
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2183-9417
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799130431947276288

Registros relacionados