NEW CONCEPTS IN ADIPOSE TISSUE AND ABDOMINAL AORTIC PATHOLOGY

Detalhes bibliográficos
Autor(a) principal: Dias-Neto, Marina
Data de Publicação: 2018
Outros Autores: Nunes, Fábio, Almeida, Glória, Ramos, José Fernando, Teixeira, José Fernando, Sampaio, Sérgio, Leite-Moreira, Adelino, Henriques-Coelho, Tiago
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.48750/acv.70
Resumo: Perivascular adipose tissue has been increasingly recognized as an important producer of vasoactive factors and cytokines that may have a direct paracrine effect on the vasculature due to the inherent proximity. In this regard, perivascular adipose tissue-vessel interaction might be identified as a novel therapeutic target of vascular diseases. Conversely to other specific adipose depots, whose characteristics have been disclosed, proprieties of abdominal periaortic adipose tissue remain obscure. Substances produced by abdominal periaortic adipose tissue may play a role in the pathologic pathways occurring in abdominal aortic aneurism and/or aortic atherosclerosis. Approaches to address this topic are fundamental steps towards innovative therapeutic strategies that address adventitia instead of the damaged intima of peripheral vessels.
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spelling NEW CONCEPTS IN ADIPOSE TISSUE AND ABDOMINAL AORTIC PATHOLOGYNOVOS CONCEITOS SOBRE ADIPOSIDADE NA PATOLOGIA DA AORTA ABDOMINALAneurisma da aorta abdominaldoença arterial periféricatecido adiposo visceraltecido adiposo periaórticoAbdominal aortic aneurysmperipheral arterial diseasevisceral adipose tissueperiaortic adipose tissuePerivascular adipose tissue has been increasingly recognized as an important producer of vasoactive factors and cytokines that may have a direct paracrine effect on the vasculature due to the inherent proximity. In this regard, perivascular adipose tissue-vessel interaction might be identified as a novel therapeutic target of vascular diseases. Conversely to other specific adipose depots, whose characteristics have been disclosed, proprieties of abdominal periaortic adipose tissue remain obscure. Substances produced by abdominal periaortic adipose tissue may play a role in the pathologic pathways occurring in abdominal aortic aneurism and/or aortic atherosclerosis. Approaches to address this topic are fundamental steps towards innovative therapeutic strategies that address adventitia instead of the damaged intima of peripheral vessels.O tecido adiposo perivascular tem tido cada vez mais reconhecimento como um importante produtor de fatores vasoativos e de citocinas que podem ter um efeito parácrino direto na vasculatura devido à sua inerente proximidade. A este respeito, a interação tecido adiposo perivascular-vaso pode ser identificada como um novo alvo terapêutico de doenças vasculares. Contrariamente a outros depósitos adiposos específicos, cuja importância tem sido crescentemente divulgada, as propriedades do tecido adiposo periaórtico abdominal permanecem obscuras. As substâncias produzidas por este compartimento adiposo podem desempenhar um papel nas vias patológicas que ocorrem em doenças como o aneurisma da aorta abdominal e/ou a aterosclerose aórtica. Abordagens para esclarecer a sua importância são passos fundamentais na definição de estratégias terapêuticas inovadoras que enderecem a adventícia em vez da íntima danificada das artérias.Sociedade Portuguesa de Angiologia e Cirurgia Vascular2018-06-07T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.48750/acv.70oai:ojs.acvjournal.com:article/70Angiologia e Cirurgia Vascular; Vol. 14 No. 2 (2018): June; 133-138Angiologia e Cirurgia Vascular; Vol. 14 N.º 2 (2018): Junho; 133-1382183-00961646-706Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttp://acvjournal.com/index.php/acv/article/view/70https://doi.org/10.48750/acv.70http://acvjournal.com/index.php/acv/article/view/70/95Copyright (c) 2018 Angiologia e Cirurgia Vascularinfo:eu-repo/semantics/openAccessDias-Neto, MarinaNunes, FábioAlmeida, GlóriaRamos, José FernandoTeixeira, José FernandoSampaio, SérgioLeite-Moreira, AdelinoHenriques-Coelho, Tiago2022-05-23T15:10:00Zoai:ojs.acvjournal.com:article/70Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T14:57:29.094416Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv NEW CONCEPTS IN ADIPOSE TISSUE AND ABDOMINAL AORTIC PATHOLOGY
NOVOS CONCEITOS SOBRE ADIPOSIDADE NA PATOLOGIA DA AORTA ABDOMINAL
title NEW CONCEPTS IN ADIPOSE TISSUE AND ABDOMINAL AORTIC PATHOLOGY
spellingShingle NEW CONCEPTS IN ADIPOSE TISSUE AND ABDOMINAL AORTIC PATHOLOGY
Dias-Neto, Marina
Aneurisma da aorta abdominal
doença arterial periférica
tecido adiposo visceral
tecido adiposo periaórtico
Abdominal aortic aneurysm
peripheral arterial disease
visceral adipose tissue
periaortic adipose tissue
title_short NEW CONCEPTS IN ADIPOSE TISSUE AND ABDOMINAL AORTIC PATHOLOGY
title_full NEW CONCEPTS IN ADIPOSE TISSUE AND ABDOMINAL AORTIC PATHOLOGY
title_fullStr NEW CONCEPTS IN ADIPOSE TISSUE AND ABDOMINAL AORTIC PATHOLOGY
title_full_unstemmed NEW CONCEPTS IN ADIPOSE TISSUE AND ABDOMINAL AORTIC PATHOLOGY
title_sort NEW CONCEPTS IN ADIPOSE TISSUE AND ABDOMINAL AORTIC PATHOLOGY
author Dias-Neto, Marina
author_facet Dias-Neto, Marina
Nunes, Fábio
Almeida, Glória
Ramos, José Fernando
Teixeira, José Fernando
Sampaio, Sérgio
Leite-Moreira, Adelino
Henriques-Coelho, Tiago
author_role author
author2 Nunes, Fábio
Almeida, Glória
Ramos, José Fernando
Teixeira, José Fernando
Sampaio, Sérgio
Leite-Moreira, Adelino
Henriques-Coelho, Tiago
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Dias-Neto, Marina
Nunes, Fábio
Almeida, Glória
Ramos, José Fernando
Teixeira, José Fernando
Sampaio, Sérgio
Leite-Moreira, Adelino
Henriques-Coelho, Tiago
dc.subject.por.fl_str_mv Aneurisma da aorta abdominal
doença arterial periférica
tecido adiposo visceral
tecido adiposo periaórtico
Abdominal aortic aneurysm
peripheral arterial disease
visceral adipose tissue
periaortic adipose tissue
topic Aneurisma da aorta abdominal
doença arterial periférica
tecido adiposo visceral
tecido adiposo periaórtico
Abdominal aortic aneurysm
peripheral arterial disease
visceral adipose tissue
periaortic adipose tissue
description Perivascular adipose tissue has been increasingly recognized as an important producer of vasoactive factors and cytokines that may have a direct paracrine effect on the vasculature due to the inherent proximity. In this regard, perivascular adipose tissue-vessel interaction might be identified as a novel therapeutic target of vascular diseases. Conversely to other specific adipose depots, whose characteristics have been disclosed, proprieties of abdominal periaortic adipose tissue remain obscure. Substances produced by abdominal periaortic adipose tissue may play a role in the pathologic pathways occurring in abdominal aortic aneurism and/or aortic atherosclerosis. Approaches to address this topic are fundamental steps towards innovative therapeutic strategies that address adventitia instead of the damaged intima of peripheral vessels.
publishDate 2018
dc.date.none.fl_str_mv 2018-06-07T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.48750/acv.70
oai:ojs.acvjournal.com:article/70
url https://doi.org/10.48750/acv.70
identifier_str_mv oai:ojs.acvjournal.com:article/70
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv http://acvjournal.com/index.php/acv/article/view/70
https://doi.org/10.48750/acv.70
http://acvjournal.com/index.php/acv/article/view/70/95
dc.rights.driver.fl_str_mv Copyright (c) 2018 Angiologia e Cirurgia Vascular
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Angiologia e Cirurgia Vascular
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
dc.source.none.fl_str_mv Angiologia e Cirurgia Vascular; Vol. 14 No. 2 (2018): June; 133-138
Angiologia e Cirurgia Vascular; Vol. 14 N.º 2 (2018): Junho; 133-138
2183-0096
1646-706X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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