Gamma irradiation effects on ochratoxin A: degradation, cytotoxicity and application in food
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/47116 |
Resumo: | Ochratoxin A (OTA) is one of the main mycotoxins that can be found in food. The use of gamma radiation is a technique for preserving food that may exert some effects on mycotoxins. OTA was irradiated in its dry form, in aqueous and in methanolic solutions, and in wheat flour, grape juice and wine. Additionally, the toxicity of OTA irradiated in water was tested. In aqueous solutions, more than 90% of the OTA was degraded by -radiation doses 2.5 kGy, and a 2-fold reduction in OTA cytotoxicity was observed. In food matrices, the elimination of OTA by -radiation was found more difficult, as radiation doses of 30 kGy eliminate at most 24% of the OTA. Higher moisture content of food matrices did not substantially increase OTA elimination. It is concluded that OTA is very sensitive to irradiation in water solutions but resistant in its dry form and in food matrices. |
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Gamma irradiation effects on ochratoxin A: degradation, cytotoxicity and application in foodOchratoxin ACytotoxicityGamma irradiationGrape juiceWheat flourWineScience & TechnologyOchratoxin A (OTA) is one of the main mycotoxins that can be found in food. The use of gamma radiation is a technique for preserving food that may exert some effects on mycotoxins. OTA was irradiated in its dry form, in aqueous and in methanolic solutions, and in wheat flour, grape juice and wine. Additionally, the toxicity of OTA irradiated in water was tested. In aqueous solutions, more than 90% of the OTA was degraded by -radiation doses 2.5 kGy, and a 2-fold reduction in OTA cytotoxicity was observed. In food matrices, the elimination of OTA by -radiation was found more difficult, as radiation doses of 30 kGy eliminate at most 24% of the OTA. Higher moisture content of food matrices did not substantially increase OTA elimination. It is concluded that OTA is very sensitive to irradiation in water solutions but resistant in its dry form and in food matrices.Thalita Calado received support through a grant SFRH/BD/79364/2011 from the Portuguese Foundation for Science and Technology (FCT –Portugal).LuísAbrunhosawassupportedbygrantUMINHO/BPD/51/ 2015 from project UID/BIO/04469/2013 financed by FCT/MEC (OE). This study was supported by the FCT under the scope of the strategic funding of UID/BIO/04469/2013 unit and COMPETE 2020 (POCI-010145-FEDER-006684) and BioTecNorte operation (NORTE-01-0145FEDER-000004) funded by European Regional Development Fund under the scope of Norte2020 - Programa Operacional Regional do Norte; and under the scope of the projects RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462) and RTA2012-00053-00-00 INIA. The C2TN/IST authors gratefully acknowledge their FCT support through projects RECI/AAG-TEC/0400/2012 and UID/Multi/04349/ 2013. The authors are grateful to Luis Alté for his excellent technical assistance.info:eu-repo/semantics/publishedVersionElsevierUniversidade do MinhoCalado, ThalitaFernández-Cruz, María LuisaVerde, Sandra CaboVenâncio, ArmandoAbrunhosa, Luís2018-022018-02-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/47116engCalado, Thalita; Fernández-Cruz, María Luisa; Verde, Sandra Cabo; Venâncio, Armando; Abrunhosa, Luís, Gamma irradiation effects on ochratoxin A: degradation, cytotoxicity and application in food. Food Chemistry, 240, 463-471, 20180308-814610.1016/j.foodchem.2017.07.13628946299http://www.elsevier.com/locate/issn/03088146info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:48:22Zoai:repositorium.sdum.uminho.pt:1822/47116Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:46:37.312415Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Gamma irradiation effects on ochratoxin A: degradation, cytotoxicity and application in food |
title |
Gamma irradiation effects on ochratoxin A: degradation, cytotoxicity and application in food |
spellingShingle |
Gamma irradiation effects on ochratoxin A: degradation, cytotoxicity and application in food Calado, Thalita Ochratoxin A Cytotoxicity Gamma irradiation Grape juice Wheat flour Wine Science & Technology |
title_short |
Gamma irradiation effects on ochratoxin A: degradation, cytotoxicity and application in food |
title_full |
Gamma irradiation effects on ochratoxin A: degradation, cytotoxicity and application in food |
title_fullStr |
Gamma irradiation effects on ochratoxin A: degradation, cytotoxicity and application in food |
title_full_unstemmed |
Gamma irradiation effects on ochratoxin A: degradation, cytotoxicity and application in food |
title_sort |
Gamma irradiation effects on ochratoxin A: degradation, cytotoxicity and application in food |
author |
Calado, Thalita |
author_facet |
Calado, Thalita Fernández-Cruz, María Luisa Verde, Sandra Cabo Venâncio, Armando Abrunhosa, Luís |
author_role |
author |
author2 |
Fernández-Cruz, María Luisa Verde, Sandra Cabo Venâncio, Armando Abrunhosa, Luís |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Calado, Thalita Fernández-Cruz, María Luisa Verde, Sandra Cabo Venâncio, Armando Abrunhosa, Luís |
dc.subject.por.fl_str_mv |
Ochratoxin A Cytotoxicity Gamma irradiation Grape juice Wheat flour Wine Science & Technology |
topic |
Ochratoxin A Cytotoxicity Gamma irradiation Grape juice Wheat flour Wine Science & Technology |
description |
Ochratoxin A (OTA) is one of the main mycotoxins that can be found in food. The use of gamma radiation is a technique for preserving food that may exert some effects on mycotoxins. OTA was irradiated in its dry form, in aqueous and in methanolic solutions, and in wheat flour, grape juice and wine. Additionally, the toxicity of OTA irradiated in water was tested. In aqueous solutions, more than 90% of the OTA was degraded by -radiation doses 2.5 kGy, and a 2-fold reduction in OTA cytotoxicity was observed. In food matrices, the elimination of OTA by -radiation was found more difficult, as radiation doses of 30 kGy eliminate at most 24% of the OTA. Higher moisture content of food matrices did not substantially increase OTA elimination. It is concluded that OTA is very sensitive to irradiation in water solutions but resistant in its dry form and in food matrices. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-02 2018-02-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/47116 |
url |
http://hdl.handle.net/1822/47116 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Calado, Thalita; Fernández-Cruz, María Luisa; Verde, Sandra Cabo; Venâncio, Armando; Abrunhosa, Luís, Gamma irradiation effects on ochratoxin A: degradation, cytotoxicity and application in food. Food Chemistry, 240, 463-471, 2018 0308-8146 10.1016/j.foodchem.2017.07.136 28946299 http://www.elsevier.com/locate/issn/03088146 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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