Coronary X-ray angiography segmentation using Artificial Intelligence: a multicentric validation study of a deep learning model

Detalhes bibliográficos
Autor(a) principal: Menezes, Miguel Nobre
Data de Publicação: 2023
Outros Autores: Silva, João Lourenço, Valente Silva, Beatriz, Rodrigues, Tiago, Guerreiro, Cláudio, Guedes, João Pedro, Santos, Manuel Oliveira, Oliveira, Arlindo L., Pinto, Fausto J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/57068
Resumo: © The Author(s) 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons. org/licenses/by/4.0/.
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spelling Coronary X-ray angiography segmentation using Artificial Intelligence: a multicentric validation study of a deep learning modelArtificial IntelligenceCoronary angiographyCoronary artery diseaseDeep learningMachine learningPercutaneous coronary intervention© The Author(s) 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons. org/licenses/by/4.0/.Introduction: We previously developed an artificial intelligence (AI) model for automatic coronary angiography (CAG) segmentation, using deep learning. To validate this approach, the model was applied to a new dataset and results are reported. Methods: Retrospective selection of patients undergoing CAG and percutaneous coronary intervention or invasive physiology assessment over a one month period from four centers. A single frame was selected from images containing a lesion with a 50-99% stenosis (visual estimation). Automatic Quantitative Coronary Analysis (QCA) was performed with a validated software. Images were then segmented by the AI model. Lesion diameters, area overlap [based on true positive (TP) and true negative (TN) pixels] and a global segmentation score (GSS - 0 -100 points) - previously developed and published - were measured. Results: 123 regions of interest from 117 images across 90 patients were included. There were no significant differences between lesion diameter, percentage diameter stenosis and distal border diameter between the original/segmented images. There was a statistically significant albeit minor difference [0,19 mm (0,09-0,28)] regarding proximal border diameter. Overlap accuracy ((TP + TN)/(TP + TN + FP + FN)), sensitivity (TP / (TP + FN)) and Dice Score (2TP / (2TP + FN + FP)) between original/segmented images was 99,9%, 95,1% and 94,8%, respectively. The GSS was 92 (87-96), similar to the previously obtained value in the training dataset. Conclusion: the AI model was capable of accurate CAG segmentation across multiple performance metrics, when applied to a multicentric validation dataset. This paves the way for future research on its clinical uses.Open access funding provided by FCT|FCCN (b-on). Cardiovascular Center of the University of Lisbon, INESC-ID / Instituto Superior Técnico, University of Lisbon.Springer NatureRepositório da Universidade de LisboaMenezes, Miguel NobreSilva, João LourençoValente Silva, BeatrizRodrigues, TiagoGuerreiro, CláudioGuedes, João PedroSantos, Manuel OliveiraOliveira, Arlindo L.Pinto, Fausto J.2023-04-11T11:11:35Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/57068engInt J Cardiovasc Imaging. 2023 Apr 71569-579410.1007/s10554-023-02839-51875-8312info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:05:06Zoai:repositorio.ul.pt:10451/57068Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:07:31.071013Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Coronary X-ray angiography segmentation using Artificial Intelligence: a multicentric validation study of a deep learning model
title Coronary X-ray angiography segmentation using Artificial Intelligence: a multicentric validation study of a deep learning model
spellingShingle Coronary X-ray angiography segmentation using Artificial Intelligence: a multicentric validation study of a deep learning model
Menezes, Miguel Nobre
Artificial Intelligence
Coronary angiography
Coronary artery disease
Deep learning
Machine learning
Percutaneous coronary intervention
title_short Coronary X-ray angiography segmentation using Artificial Intelligence: a multicentric validation study of a deep learning model
title_full Coronary X-ray angiography segmentation using Artificial Intelligence: a multicentric validation study of a deep learning model
title_fullStr Coronary X-ray angiography segmentation using Artificial Intelligence: a multicentric validation study of a deep learning model
title_full_unstemmed Coronary X-ray angiography segmentation using Artificial Intelligence: a multicentric validation study of a deep learning model
title_sort Coronary X-ray angiography segmentation using Artificial Intelligence: a multicentric validation study of a deep learning model
author Menezes, Miguel Nobre
author_facet Menezes, Miguel Nobre
Silva, João Lourenço
Valente Silva, Beatriz
Rodrigues, Tiago
Guerreiro, Cláudio
Guedes, João Pedro
Santos, Manuel Oliveira
Oliveira, Arlindo L.
Pinto, Fausto J.
author_role author
author2 Silva, João Lourenço
Valente Silva, Beatriz
Rodrigues, Tiago
Guerreiro, Cláudio
Guedes, João Pedro
Santos, Manuel Oliveira
Oliveira, Arlindo L.
Pinto, Fausto J.
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Menezes, Miguel Nobre
Silva, João Lourenço
Valente Silva, Beatriz
Rodrigues, Tiago
Guerreiro, Cláudio
Guedes, João Pedro
Santos, Manuel Oliveira
Oliveira, Arlindo L.
Pinto, Fausto J.
dc.subject.por.fl_str_mv Artificial Intelligence
Coronary angiography
Coronary artery disease
Deep learning
Machine learning
Percutaneous coronary intervention
topic Artificial Intelligence
Coronary angiography
Coronary artery disease
Deep learning
Machine learning
Percutaneous coronary intervention
description © The Author(s) 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons. org/licenses/by/4.0/.
publishDate 2023
dc.date.none.fl_str_mv 2023-04-11T11:11:35Z
2023
2023-01-01T00:00:00Z
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/57068
url http://hdl.handle.net/10451/57068
dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv Int J Cardiovasc Imaging. 2023 Apr 7
1569-5794
10.1007/s10554-023-02839-5
1875-8312
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dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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