Pharmacological properties of Tilia europeæ aqueous: screening anxiolytic/sedative activity in mice
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/14662 |
Resumo: | The extracts or infusions obtained from inflorescences of Tilia europeae have been used in popular medicine as a sedative/anxiolytic drug. The purpose of the present work was to evaluate these possible properties of this extract, by using different behavioural models. The extract, orally administered to mice, prolonged sleeping time, changed the level of anxiety, affected curiosity and locomotor activity and showed miorrelaxant properties. |
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Pharmacological properties of Tilia europeæ aqueous: screening anxiolytic/sedative activity in miceTilia europeaeAnxiolytic effectSedationLocomotionExplorationThe extracts or infusions obtained from inflorescences of Tilia europeae have been used in popular medicine as a sedative/anxiolytic drug. The purpose of the present work was to evaluate these possible properties of this extract, by using different behavioural models. The extract, orally administered to mice, prolonged sleeping time, changed the level of anxiety, affected curiosity and locomotor activity and showed miorrelaxant properties.JNICT PBIC/C/SAU/1607/92Universidade de Coimbra. Faculdade de Medicina2005info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/14662http://hdl.handle.net/10316/14662engCOTRIM, M. D. [et al.] - Pharmacological properties of Tilia europeæ aqueous: screening anxiolytic/sedative activity in mice. "Arquivos de patologia geral e anatomia patológica da Universidade de Coimbra". ISSN 0066-7854. Vol. 31 (2005) 23-250066-7854Cotrim, M. D.Figueiredo, I. V.Cavadas, C.Cunha, A. Proença daCaramona, M. M.Macedo, T. R. A.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-05-25T09:46:50Zoai:estudogeral.uc.pt:10316/14662Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:47:29.769255Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Pharmacological properties of Tilia europeæ aqueous: screening anxiolytic/sedative activity in mice |
title |
Pharmacological properties of Tilia europeæ aqueous: screening anxiolytic/sedative activity in mice |
spellingShingle |
Pharmacological properties of Tilia europeæ aqueous: screening anxiolytic/sedative activity in mice Cotrim, M. D. Tilia europeae Anxiolytic effect Sedation Locomotion Exploration |
title_short |
Pharmacological properties of Tilia europeæ aqueous: screening anxiolytic/sedative activity in mice |
title_full |
Pharmacological properties of Tilia europeæ aqueous: screening anxiolytic/sedative activity in mice |
title_fullStr |
Pharmacological properties of Tilia europeæ aqueous: screening anxiolytic/sedative activity in mice |
title_full_unstemmed |
Pharmacological properties of Tilia europeæ aqueous: screening anxiolytic/sedative activity in mice |
title_sort |
Pharmacological properties of Tilia europeæ aqueous: screening anxiolytic/sedative activity in mice |
author |
Cotrim, M. D. |
author_facet |
Cotrim, M. D. Figueiredo, I. V. Cavadas, C. Cunha, A. Proença da Caramona, M. M. Macedo, T. R. A. |
author_role |
author |
author2 |
Figueiredo, I. V. Cavadas, C. Cunha, A. Proença da Caramona, M. M. Macedo, T. R. A. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Cotrim, M. D. Figueiredo, I. V. Cavadas, C. Cunha, A. Proença da Caramona, M. M. Macedo, T. R. A. |
dc.subject.por.fl_str_mv |
Tilia europeae Anxiolytic effect Sedation Locomotion Exploration |
topic |
Tilia europeae Anxiolytic effect Sedation Locomotion Exploration |
description |
The extracts or infusions obtained from inflorescences of Tilia europeae have been used in popular medicine as a sedative/anxiolytic drug. The purpose of the present work was to evaluate these possible properties of this extract, by using different behavioural models. The extract, orally administered to mice, prolonged sleeping time, changed the level of anxiety, affected curiosity and locomotor activity and showed miorrelaxant properties. |
publishDate |
2005 |
dc.date.none.fl_str_mv |
2005 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/14662 http://hdl.handle.net/10316/14662 |
url |
http://hdl.handle.net/10316/14662 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
COTRIM, M. D. [et al.] - Pharmacological properties of Tilia europeæ aqueous: screening anxiolytic/sedative activity in mice. "Arquivos de patologia geral e anatomia patológica da Universidade de Coimbra". ISSN 0066-7854. Vol. 31 (2005) 23-25 0066-7854 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Universidade de Coimbra. Faculdade de Medicina |
publisher.none.fl_str_mv |
Universidade de Coimbra. Faculdade de Medicina |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133752171954176 |