The antioxidant activity of prenylflavonoids
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/25799 |
Resumo: | Prenylated flavonoids combine the flavonoid moiety and the lipophilic prenyl side-chain. A great number of derivatives belonging to the class of chalcones, flavones, flavanones, isoflavones and other complex structures possessing di erent prenylation patterns have been studied in the past two decades for their potential as antioxidant agents. In this review, current knowledge on the natural occurrence and structural characteristics of both natural and synthetic derivatives was compiled. An exhaustive survey on the methods used to evaluate the antioxidant potential of these prenylflavonoids and the main results obtained were also presented and discussed. Whenever possible, structure-activity relationships were explored. |
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The antioxidant activity of prenylflavonoidsABTS assayChelation studiesDPPH radicalFlavonoidsFRAPLipid peroxidationNatural productsPrenylROSPrenylated flavonoids combine the flavonoid moiety and the lipophilic prenyl side-chain. A great number of derivatives belonging to the class of chalcones, flavones, flavanones, isoflavones and other complex structures possessing di erent prenylation patterns have been studied in the past two decades for their potential as antioxidant agents. In this review, current knowledge on the natural occurrence and structural characteristics of both natural and synthetic derivatives was compiled. An exhaustive survey on the methods used to evaluate the antioxidant potential of these prenylflavonoids and the main results obtained were also presented and discussed. Whenever possible, structure-activity relationships were explored.The authors are grateful to FCT/MEC, Fundação para a Ciência e Tecnologia and Ministério da Educação e Ciência, Portugal and FEDER, the Partnership Agreement PT2020, for financial support to CIMO (UID/AGR/00690/2019) and QOPNA (UID/QUI/00062/2019) as well as project POCI-01-0145-FEDER-016385. Acknowledgments: Thanks are due to University of Aveiro and Instituto Politécnico de Bragança for all support.MDPIBiblioteca Digital do IPBSantos, Clementina M.M.Silva, Artur2022-08-02T14:16:22Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/25799engSantos, Clementina M.M.; Silva, Artur (2020). The antioxidant activity of prenylflavonoids. Molecules. EISSN 1420-3049. 25:3, p. 1-3310.3390/molecules250306961420-3049info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:57:41Zoai:bibliotecadigital.ipb.pt:10198/25799Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:16:24.297643Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The antioxidant activity of prenylflavonoids |
title |
The antioxidant activity of prenylflavonoids |
spellingShingle |
The antioxidant activity of prenylflavonoids Santos, Clementina M.M. ABTS assay Chelation studies DPPH radical Flavonoids FRAP Lipid peroxidation Natural products Prenyl ROS |
title_short |
The antioxidant activity of prenylflavonoids |
title_full |
The antioxidant activity of prenylflavonoids |
title_fullStr |
The antioxidant activity of prenylflavonoids |
title_full_unstemmed |
The antioxidant activity of prenylflavonoids |
title_sort |
The antioxidant activity of prenylflavonoids |
author |
Santos, Clementina M.M. |
author_facet |
Santos, Clementina M.M. Silva, Artur |
author_role |
author |
author2 |
Silva, Artur |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Santos, Clementina M.M. Silva, Artur |
dc.subject.por.fl_str_mv |
ABTS assay Chelation studies DPPH radical Flavonoids FRAP Lipid peroxidation Natural products Prenyl ROS |
topic |
ABTS assay Chelation studies DPPH radical Flavonoids FRAP Lipid peroxidation Natural products Prenyl ROS |
description |
Prenylated flavonoids combine the flavonoid moiety and the lipophilic prenyl side-chain. A great number of derivatives belonging to the class of chalcones, flavones, flavanones, isoflavones and other complex structures possessing di erent prenylation patterns have been studied in the past two decades for their potential as antioxidant agents. In this review, current knowledge on the natural occurrence and structural characteristics of both natural and synthetic derivatives was compiled. An exhaustive survey on the methods used to evaluate the antioxidant potential of these prenylflavonoids and the main results obtained were also presented and discussed. Whenever possible, structure-activity relationships were explored. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020 2020-01-01T00:00:00Z 2022-08-02T14:16:22Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/25799 |
url |
http://hdl.handle.net/10198/25799 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Santos, Clementina M.M.; Silva, Artur (2020). The antioxidant activity of prenylflavonoids. Molecules. EISSN 1420-3049. 25:3, p. 1-33 10.3390/molecules25030696 1420-3049 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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application/pdf |
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MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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