Tissue oxygen demand in regulation of the behavior of the cells in the vasculature

Detalhes bibliográficos
Autor(a) principal: Barvitenko, Nadezhda N.
Data de Publicação: 2013
Outros Autores: Aslam, Muhammad, Filosa, Jessica, Matteucci, Elena, Nikinmaa, Mikko, Pantaleo, Antonella, Saldanha, Carlota, Baskurt, Oguz K.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/10674
Resumo: © 2013 John Wiley & Sons Ltd
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spelling Tissue oxygen demand in regulation of the behavior of the cells in the vasculatureMicrovascular blood flowTissue oxygen demandRed blood cellEndothelial cellVascular smooth muscle cellRegulation© 2013 John Wiley & Sons LtdThe control of arteriolar diameters in microvasculature has been in the focus of studies on mechanisms matching oxygen demand and supply at the tissue level. Functionally, important vascular elements include EC, VSMC, and RBC. Integration of these different cell types into functional units aimed at matching tissue oxygen supply with tissue oxygen demand is only achieved when all these cells can respond to the signals of tissue oxygen demand. Many vasoactive agents that serve as signals of tissue oxygen demand have their receptors on all these types of cells (VSMC, EC, and RBC) implying that there can be a coordinated regulation of their behavior by the tissue oxygen demand. Such functions of RBC as oxygen carrying by Hb, rheology, and release of vasoactive agents are considered. Several common extra- and intracellular signaling pathways that link tissue oxygen demand with control of VSMC contractility, EC permeability, and RBC functioning are discussed.John Wiley & SonsRepositório da Universidade de LisboaBarvitenko, Nadezhda N.Aslam, MuhammadFilosa, JessicaMatteucci, ElenaNikinmaa, MikkoPantaleo, AntonellaSaldanha, CarlotaBaskurt, Oguz K.2014-03-04T16:54:34Z20132013-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/10674engMicrocirculation 20: 484–501, 20131073-9688http://dx.doi.org/10.1111/micc.12052metadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T15:56:19Zoai:repositorio.ul.pt:10451/10674Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:34:37.072854Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Tissue oxygen demand in regulation of the behavior of the cells in the vasculature
title Tissue oxygen demand in regulation of the behavior of the cells in the vasculature
spellingShingle Tissue oxygen demand in regulation of the behavior of the cells in the vasculature
Barvitenko, Nadezhda N.
Microvascular blood flow
Tissue oxygen demand
Red blood cell
Endothelial cell
Vascular smooth muscle cell
Regulation
title_short Tissue oxygen demand in regulation of the behavior of the cells in the vasculature
title_full Tissue oxygen demand in regulation of the behavior of the cells in the vasculature
title_fullStr Tissue oxygen demand in regulation of the behavior of the cells in the vasculature
title_full_unstemmed Tissue oxygen demand in regulation of the behavior of the cells in the vasculature
title_sort Tissue oxygen demand in regulation of the behavior of the cells in the vasculature
author Barvitenko, Nadezhda N.
author_facet Barvitenko, Nadezhda N.
Aslam, Muhammad
Filosa, Jessica
Matteucci, Elena
Nikinmaa, Mikko
Pantaleo, Antonella
Saldanha, Carlota
Baskurt, Oguz K.
author_role author
author2 Aslam, Muhammad
Filosa, Jessica
Matteucci, Elena
Nikinmaa, Mikko
Pantaleo, Antonella
Saldanha, Carlota
Baskurt, Oguz K.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Barvitenko, Nadezhda N.
Aslam, Muhammad
Filosa, Jessica
Matteucci, Elena
Nikinmaa, Mikko
Pantaleo, Antonella
Saldanha, Carlota
Baskurt, Oguz K.
dc.subject.por.fl_str_mv Microvascular blood flow
Tissue oxygen demand
Red blood cell
Endothelial cell
Vascular smooth muscle cell
Regulation
topic Microvascular blood flow
Tissue oxygen demand
Red blood cell
Endothelial cell
Vascular smooth muscle cell
Regulation
description © 2013 John Wiley & Sons Ltd
publishDate 2013
dc.date.none.fl_str_mv 2013
2013-01-01T00:00:00Z
2014-03-04T16:54:34Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/10674
url http://hdl.handle.net/10451/10674
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Microcirculation 20: 484–501, 2013
1073-9688
http://dx.doi.org/10.1111/micc.12052
dc.rights.driver.fl_str_mv metadata only access
info:eu-repo/semantics/openAccess
rights_invalid_str_mv metadata only access
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv John Wiley & Sons
publisher.none.fl_str_mv John Wiley & Sons
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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