Metacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal Collection

Detalhes bibliográficos
Autor(a) principal: Curate, Francisco
Data de Publicação: 2019
Outros Autores: Perinha, Andreia, Silva, Ana Maria, Cunha, Eugenia, Umbelino, Cláudia, Nogueira, Catarina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.1/14485
Resumo: There has been considerable progress in recent years in our understanding of the patterns of cortical bone loss in the second metacarpal in archeological skeletal samples. Nevertheless, cortical data from reference skeletal collections are insufficient, and the possible connection of metacarpal cortical parameters with osteoporotic fractures has not been thoroughly addressed. As such, this article aims to identify and explain sex-specific and age-associated metacarpal cortical bone loss in a large sample (N = 302
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spelling Metacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal CollectionX-ray radiogrammetryMajor gene-controlHip-fracturesCompression fracturesAgeWomenEpidemiologyMenopauseGeometryIndexThere has been considerable progress in recent years in our understanding of the patterns of cortical bone loss in the second metacarpal in archeological skeletal samples. Nevertheless, cortical data from reference skeletal collections are insufficient, and the possible connection of metacarpal cortical parameters with osteoporotic fractures has not been thoroughly addressed. As such, this article aims to identify and explain sex-specific and age-associated metacarpal cortical bone loss in a large sample (N = 302females: 154/males: 148) from the Coimbra Identified Skeletal Collection. Another objective is to evaluate the association of cortical and demographic features with osteoporotic fractures. Age-related endocortical bone loss is significant in women but not evident in men. Periosteal accretion of the bone is absent in both sexes. Overall, there is a net loss of the cortical bone in women, whereas cortical bone strength seems to be preserved in men. The prevalence of osteoporotic fractures is similar in both sexes, with age at death significantly influencing the probability of exhibiting a fracture. Metacarpal cortical index does not seem to be an independent risk factor for osteoporotic fractures in this sample.Fundacao para a Ciencia e a TecnologiaPortuguese Foundation for Science and Technology [SFRH/BPD/74015/2010]WileySapientiaCurate, FranciscoPerinha, AndreiaSilva, Ana MariaCunha, EugeniaUmbelino, CláudiaNogueira, Catarina2020-07-24T10:53:23Z2019-012019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/14485eng1047-482X10.1002/oa.2717info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-24T10:26:47Zoai:sapientia.ualg.pt:10400.1/14485Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:05:31.121133Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Metacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal Collection
title Metacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal Collection
spellingShingle Metacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal Collection
Curate, Francisco
X-ray radiogrammetry
Major gene-control
Hip-fractures
Compression fractures
Age
Women
Epidemiology
Menopause
Geometry
Index
title_short Metacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal Collection
title_full Metacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal Collection
title_fullStr Metacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal Collection
title_full_unstemmed Metacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal Collection
title_sort Metacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal Collection
author Curate, Francisco
author_facet Curate, Francisco
Perinha, Andreia
Silva, Ana Maria
Cunha, Eugenia
Umbelino, Cláudia
Nogueira, Catarina
author_role author
author2 Perinha, Andreia
Silva, Ana Maria
Cunha, Eugenia
Umbelino, Cláudia
Nogueira, Catarina
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Sapientia
dc.contributor.author.fl_str_mv Curate, Francisco
Perinha, Andreia
Silva, Ana Maria
Cunha, Eugenia
Umbelino, Cláudia
Nogueira, Catarina
dc.subject.por.fl_str_mv X-ray radiogrammetry
Major gene-control
Hip-fractures
Compression fractures
Age
Women
Epidemiology
Menopause
Geometry
Index
topic X-ray radiogrammetry
Major gene-control
Hip-fractures
Compression fractures
Age
Women
Epidemiology
Menopause
Geometry
Index
description There has been considerable progress in recent years in our understanding of the patterns of cortical bone loss in the second metacarpal in archeological skeletal samples. Nevertheless, cortical data from reference skeletal collections are insufficient, and the possible connection of metacarpal cortical parameters with osteoporotic fractures has not been thoroughly addressed. As such, this article aims to identify and explain sex-specific and age-associated metacarpal cortical bone loss in a large sample (N = 302
publishDate 2019
dc.date.none.fl_str_mv 2019-01
2019-01-01T00:00:00Z
2020-07-24T10:53:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.1/14485
url http://hdl.handle.net/10400.1/14485
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1047-482X
10.1002/oa.2717
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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