The contribution of the diffusion-weitghted imaging in breast carcinoma diagnosis

• Autor(a) principal: Tinoco, Paulo
• Data de Publicação: 2022
• Outros Autores: Ferreira, Ana Filipa
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://doi.org/10.46885/roentgen.v3i2.80
• topic: diffusion-weighted imaging; ADC maps; apparent diffusion coefficient; breast cancer; breast carcinoma; breast MRI; breast lesions; Difusão; mapas de ADC; coeficientes aparentes de difusão; carcinoma da mama; RM mamária; lesões mamárias.

Objective: To investigate the mean apparent diffusion coefficient values ​​of different tissues and their real capability in distinguish the different types of histological tissues of breast lesions. Materials and Methods: A descriptive and correlational research has been developed in which apparent diffusion coefficient values of breast MRI examinations, performed in a public radiology service, has been collected. The sample included 31 patients, between 32 and 75 years old, with breast lesions confirmed by biopsy or surgical specimen. The treatment and statistical analysis were carried out using Excel and SPSS. Results: Benign lesions had mean apparent diffusion coefficient values ​​of 1.58 x10-3mm2/s, while malignant lesions had mean apparent diffusion coefficient values ​​of 0.89 x10-3mm2/s. Regarding to the various types of histological tissues, we found mean apparent diffusion coefficient values ​​for invasive ductal carcinoma of 0.87x10-3mm2/s, 0.99x10-3mm2/s for ductal carcinoma in situ, and 0.85x10- 3 mm2/s for invasive lobular carcinoma. Conclusion: The results demonstrate that the apparent diffusion coefficient values enable to differentiate between benign lesions, malignant lesions and healthy fibroglandular tissue, but it was not possible to set ranges of apparent diffusion coefficient values between the different histological types of lesions. We could only identify ranges of apparent diffusion coefficient values between malignant lesions and healthy fibroglandular tissue.