LATE CUTANEOUS METASTASES FROM GASTRIC CARCINOMA
Autor(a) principal: | |
---|---|
Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.34635/rpc.822 |
Resumo: | Cutaneous metastases from primary gastric carcinoma are uncommon, generally occur late in the course of the disease and have a poor prognosis. We report a long-term survival of a patient with cutaneous metastases from a gastric carcinoma. A 56-year-old patient, previously diagnosed with a poorly differentiated signet-ring cell gastric carcinoma staged as ypT3N3aM0, who underwent total gastrectomy with Roux-en-y reconstruction and extended lymphadenectomy (D2) 7 years prior, with no evidence of disease recurrence. At presentation, physical examination revealed firm erythematous nodular lesions in the face and neck, and palpable adenopathy in the left axilla. Laboratory workup showed mild anemia, and the tumour markers were negative. The staging PET-CT scan revealed left axillary and right inguinal lymph nodes metastases. The patient underwent a complete resection of the facial lesion, and the histopathology of the specimen was compatible with cutaneous metastases of signet-ring cell gastric adenocarcinoma. The patient received postoperative chemotherapy with clinical remission at 24 months follow-up. This case report of long-term survival in a metastatic gastric carcinoma emphasizes that although cutaneous metastases are rare, they should be considered when assessing suspicious lesions in patients with a history of gastric carcinoma. |
id |
RCAP_81eb851f08232f8f376cdbc0e5146cbd |
---|---|
oai_identifier_str |
oai:revista.spcir.com:article/822 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
LATE CUTANEOUS METASTASES FROM GASTRIC CARCINOMAMETÁSTASE CUTÂNEA TARDIA DE ADENOCARCINOMA GÁSTRICOCutaneous metastases from primary gastric carcinoma are uncommon, generally occur late in the course of the disease and have a poor prognosis. We report a long-term survival of a patient with cutaneous metastases from a gastric carcinoma. A 56-year-old patient, previously diagnosed with a poorly differentiated signet-ring cell gastric carcinoma staged as ypT3N3aM0, who underwent total gastrectomy with Roux-en-y reconstruction and extended lymphadenectomy (D2) 7 years prior, with no evidence of disease recurrence. At presentation, physical examination revealed firm erythematous nodular lesions in the face and neck, and palpable adenopathy in the left axilla. Laboratory workup showed mild anemia, and the tumour markers were negative. The staging PET-CT scan revealed left axillary and right inguinal lymph nodes metastases. The patient underwent a complete resection of the facial lesion, and the histopathology of the specimen was compatible with cutaneous metastases of signet-ring cell gastric adenocarcinoma. The patient received postoperative chemotherapy with clinical remission at 24 months follow-up. This case report of long-term survival in a metastatic gastric carcinoma emphasizes that although cutaneous metastases are rare, they should be considered when assessing suspicious lesions in patients with a history of gastric carcinoma.As metástases cutâneas de adenocarcinoma gástrico são raras e apresentam-se mais frequentemente num estadio tardio da doença. Apresentamos o caso clínico de um doente do sexo masculino, de 56 anos, com antecedentes de adenocarcinoma pouco diferenciado da pequena curvatura gástrica estadiado como ypT3N3aM0, em 2011, submetido a gastrectomia total com montagem em Y-de-Roux e linfadectomia D2. Realizou quimioterapia peri-operatória (epirrubicina, oxaliplatina e capecitabina). Follow-up clínico, analítico e imagiológico sem evidência de recidiva, aos 7 anos pós-diagnóstico. Ao exame objectivo, com adenopatia palpável na região axilar esquerda. Analiticamente com discreta anemia, sem elevação dos marcadores tumorais. Proposta excisão das lesões, em Consulta de Decisão Terapêutica, revelando metastização cutânea de primário gástrico. A TAC toraco-abdomino-pélvica e a PET revelaram metastização ganglionar axilar esquerda e inguinal direita. Realizou quimioterapia adjuvante, com boa resposta. Este caso mostra que as metástases cutâneas, embora raras, devem ser consideradas na avaliação de lesões suspeitas em doentes com história de carcinoma gástrico.Sociedade Portuguesa de Cirurgia2022-03-13info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.34635/rpc.822https://doi.org/10.34635/rpc.822Revista Portuguesa de Cirurgia; No 52 (2022): Número 52 - Janeiro 2022; 1-5Revista Portuguesa de Cirurgia; No 52 (2022): Número 52 - Janeiro 2022; 1-52183-11651646-6918reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://revista.spcir.com/index.php/spcir/article/view/822https://revista.spcir.com/index.php/spcir/article/view/822/632Copyright (c) 2022 Revista Portuguesa de Cirurgiainfo:eu-repo/semantics/openAccessPinto, JoséDuarte, LilianaFerreira, MartaSimão, RosaMarques, ConceiçãoPinheiro, Luís FilipeCasimiro, Carlos2024-03-14T22:05:09Zoai:revista.spcir.com:article/822Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T04:00:50.081524Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
LATE CUTANEOUS METASTASES FROM GASTRIC CARCINOMA METÁSTASE CUTÂNEA TARDIA DE ADENOCARCINOMA GÁSTRICO |
title |
LATE CUTANEOUS METASTASES FROM GASTRIC CARCINOMA |
spellingShingle |
LATE CUTANEOUS METASTASES FROM GASTRIC CARCINOMA Pinto, José |
title_short |
LATE CUTANEOUS METASTASES FROM GASTRIC CARCINOMA |
title_full |
LATE CUTANEOUS METASTASES FROM GASTRIC CARCINOMA |
title_fullStr |
LATE CUTANEOUS METASTASES FROM GASTRIC CARCINOMA |
title_full_unstemmed |
LATE CUTANEOUS METASTASES FROM GASTRIC CARCINOMA |
title_sort |
LATE CUTANEOUS METASTASES FROM GASTRIC CARCINOMA |
author |
Pinto, José |
author_facet |
Pinto, José Duarte, Liliana Ferreira, Marta Simão, Rosa Marques, Conceição Pinheiro, Luís Filipe Casimiro, Carlos |
author_role |
author |
author2 |
Duarte, Liliana Ferreira, Marta Simão, Rosa Marques, Conceição Pinheiro, Luís Filipe Casimiro, Carlos |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Pinto, José Duarte, Liliana Ferreira, Marta Simão, Rosa Marques, Conceição Pinheiro, Luís Filipe Casimiro, Carlos |
description |
Cutaneous metastases from primary gastric carcinoma are uncommon, generally occur late in the course of the disease and have a poor prognosis. We report a long-term survival of a patient with cutaneous metastases from a gastric carcinoma. A 56-year-old patient, previously diagnosed with a poorly differentiated signet-ring cell gastric carcinoma staged as ypT3N3aM0, who underwent total gastrectomy with Roux-en-y reconstruction and extended lymphadenectomy (D2) 7 years prior, with no evidence of disease recurrence. At presentation, physical examination revealed firm erythematous nodular lesions in the face and neck, and palpable adenopathy in the left axilla. Laboratory workup showed mild anemia, and the tumour markers were negative. The staging PET-CT scan revealed left axillary and right inguinal lymph nodes metastases. The patient underwent a complete resection of the facial lesion, and the histopathology of the specimen was compatible with cutaneous metastases of signet-ring cell gastric adenocarcinoma. The patient received postoperative chemotherapy with clinical remission at 24 months follow-up. This case report of long-term survival in a metastatic gastric carcinoma emphasizes that although cutaneous metastases are rare, they should be considered when assessing suspicious lesions in patients with a history of gastric carcinoma. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-03-13 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.34635/rpc.822 https://doi.org/10.34635/rpc.822 |
url |
https://doi.org/10.34635/rpc.822 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://revista.spcir.com/index.php/spcir/article/view/822 https://revista.spcir.com/index.php/spcir/article/view/822/632 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Revista Portuguesa de Cirurgia info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Revista Portuguesa de Cirurgia |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Cirurgia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Cirurgia |
dc.source.none.fl_str_mv |
Revista Portuguesa de Cirurgia; No 52 (2022): Número 52 - Janeiro 2022; 1-5 Revista Portuguesa de Cirurgia; No 52 (2022): Número 52 - Janeiro 2022; 1-5 2183-1165 1646-6918 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799138182822887424 |