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spelling Multinational evidence-based recommendations for pain management by pharmacotherapy in inflammatory arthritisIntegrating systematic literature research and expert opinion of a broad panel of rheumatologists in the 3e initiativeAnalgesicsArthritisEvidence-based medicineRheumatologyPharmacology (medical)Funding Information: Funding: This work was supported by Abbott with an unrestricted educational grant.Objective. To develop evidence-based recommendations for pain management by pharmacotherapy in patients with inflammatory arthritis (IA).Methods. A total of 453 rheumatologists from 17 countries participated in the 2010 3e (Evidence, Expertise, Exchange) Initiative. Using a formal voting process, 89 rheumatologists representing all 17 countries selected 10 clinical questions regarding the use of pain medications in IA. Bibliographic fellows undertook a systematic literature review for each question, using MEDLINE, EMBASE, Cochrane CENTRAL and 2008-09 European League Against Rheumatism (EULAR)/ACR abstracts. Relevant studies were retrieved for data extraction and quality assessment. Rheumatologists from each country used this evidence to develop a set of national recommendations. Multinational recommendations were then formulated and assessed for agreement and the potential impact on clinical practice.Results. A total of 49 242 references were identified, from which 167 studies were included in the systematic reviews. One clinical question regarding different comorbidities was divided into two separate reviews, resulting in 11 recommendations in total. Oxford levels of evidence were applied to each recommendation. The recommendations related to the efficacy and safety of various analgesic medications, pain measurement scales and pain management in the pre-conception period, pregnancy and lactation. Finally, an algorithm for the pharmacological management of pain in IA was developed. Twenty per cent of rheumatologists reported that the algorithm would change their practice, and 75% felt the algorithm was in accordance with their current practice.Conclusions. Eleven evidence-based recommendations on the management of pain by pharmacotherapy in IA were developed. They are supported by a large panel of rheumatologists from 17 countries, thus enhancing their utility in clinical practice.Centro de Estudos de Doenças Crónicas (CEDOC)NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNWhittle, Samuel L.Colebatch, Alexandra N.Buchbinder, RachelleEdwards, Christopher J.Adams, KarenEnglbrecht, MatthiasHazlewood, GlenMarks, Jonathan L.Radner, HelgaRamiro, SofiaRichards, Bethan L.Tarner, Ingo H.Aletaha, DanielBombardier, ClaireLandewé, Robert B.Müller-ladner, UlfBijlsma, Johannes W.J.Branco, JaimeBykerk, Vivian P.Da rocha castelar pinheiro, GeraldoCatrina, Anca I.Hannonen, PekkaKiely, PatrickLeeb, BurkhardLie, ElisabethMartinez-osuna, PíndaroMontecucco, Carlomaurizioøstergaard, MikkelWesthovens, ReneZochling, JaneVan der heijde, Désirée2022-11-10T22:13:33Z2012-082012-08-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10application/pdfhttp://hdl.handle.net/10362/145400eng1462-0324PURE: 47673137https://doi.org/10.1093/rheumatology/kes032info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:25:46Zoai:run.unl.pt:10362/145400Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:52:03.780163Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Multinational evidence-based recommendations for pain management by pharmacotherapy in inflammatory arthritis
Integrating systematic literature research and expert opinion of a broad panel of rheumatologists in the 3e initiative
title Multinational evidence-based recommendations for pain management by pharmacotherapy in inflammatory arthritis
spellingShingle Multinational evidence-based recommendations for pain management by pharmacotherapy in inflammatory arthritis
Whittle, Samuel L.
Analgesics
Arthritis
Evidence-based medicine
Rheumatology
Pharmacology (medical)
title_short Multinational evidence-based recommendations for pain management by pharmacotherapy in inflammatory arthritis
title_full Multinational evidence-based recommendations for pain management by pharmacotherapy in inflammatory arthritis
title_fullStr Multinational evidence-based recommendations for pain management by pharmacotherapy in inflammatory arthritis
title_full_unstemmed Multinational evidence-based recommendations for pain management by pharmacotherapy in inflammatory arthritis
title_sort Multinational evidence-based recommendations for pain management by pharmacotherapy in inflammatory arthritis
author Whittle, Samuel L.
author_facet Whittle, Samuel L.
Colebatch, Alexandra N.
Buchbinder, Rachelle
Edwards, Christopher J.
Adams, Karen
Englbrecht, Matthias
Hazlewood, Glen
Marks, Jonathan L.
Radner, Helga
Ramiro, Sofia
Richards, Bethan L.
Tarner, Ingo H.
Aletaha, Daniel
Bombardier, Claire
Landewé, Robert B.
Müller-ladner, Ulf
Bijlsma, Johannes W.J.
Branco, Jaime
Bykerk, Vivian P.
Da rocha castelar pinheiro, Geraldo
Catrina, Anca I.
Hannonen, Pekka
Kiely, Patrick
Leeb, Burkhard
Lie, Elisabeth
Martinez-osuna, Píndaro
Montecucco, Carlomaurizio
østergaard, Mikkel
Westhovens, Rene
Zochling, Jane
Van der heijde, Désirée
author_role author
author2 Colebatch, Alexandra N.
Buchbinder, Rachelle
Edwards, Christopher J.
Adams, Karen
Englbrecht, Matthias
Hazlewood, Glen
Marks, Jonathan L.
Radner, Helga
Ramiro, Sofia
Richards, Bethan L.
Tarner, Ingo H.
Aletaha, Daniel
Bombardier, Claire
Landewé, Robert B.
Müller-ladner, Ulf
Bijlsma, Johannes W.J.
Branco, Jaime
Bykerk, Vivian P.
Da rocha castelar pinheiro, Geraldo
Catrina, Anca I.
Hannonen, Pekka
Kiely, Patrick
Leeb, Burkhard
Lie, Elisabeth
Martinez-osuna, Píndaro
Montecucco, Carlomaurizio
østergaard, Mikkel
Westhovens, Rene
Zochling, Jane
Van der heijde, Désirée
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
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dc.contributor.none.fl_str_mv Centro de Estudos de Doenças Crónicas (CEDOC)
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Whittle, Samuel L.
Colebatch, Alexandra N.
Buchbinder, Rachelle
Edwards, Christopher J.
Adams, Karen
Englbrecht, Matthias
Hazlewood, Glen
Marks, Jonathan L.
Radner, Helga
Ramiro, Sofia
Richards, Bethan L.
Tarner, Ingo H.
Aletaha, Daniel
Bombardier, Claire
Landewé, Robert B.
Müller-ladner, Ulf
Bijlsma, Johannes W.J.
Branco, Jaime
Bykerk, Vivian P.
Da rocha castelar pinheiro, Geraldo
Catrina, Anca I.
Hannonen, Pekka
Kiely, Patrick
Leeb, Burkhard
Lie, Elisabeth
Martinez-osuna, Píndaro
Montecucco, Carlomaurizio
østergaard, Mikkel
Westhovens, Rene
Zochling, Jane
Van der heijde, Désirée
dc.subject.por.fl_str_mv Analgesics
Arthritis
Evidence-based medicine
Rheumatology
Pharmacology (medical)
topic Analgesics
Arthritis
Evidence-based medicine
Rheumatology
Pharmacology (medical)
description Funding Information: Funding: This work was supported by Abbott with an unrestricted educational grant.
publishDate 2012
dc.date.none.fl_str_mv 2012-08
2012-08-01T00:00:00Z
2022-11-10T22:13:33Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/145400
url http://hdl.handle.net/10362/145400
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1462-0324
PURE: 47673137
https://doi.org/10.1093/rheumatology/kes032
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eu_rights_str_mv openAccess
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