Development of a sheep vertebroplasty model for bioceramic materials assessment
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo de conferência |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10174/12506 |
Resumo: | Development of a sheep vertebroplasty model for bioceramic materials assessment Sheep has been widely used as an animal orthopaedic model. Although several studies report anatomic and biomechanical similarities as well as distinctions of ovine lumbar vertebrae when compared to human’s, only a few studies describe its actual use as a vertebroplasty model. Due to distinct anatomic features, sheep lumbar vertebrae pose a challenge when developing a minimally invasive procedure for vertebroplasty material testing, under conditions meant to be the most similar to clinical procedure. The present work describes the development of an appropriate surgical percutaneous vertebroplasty model in the lumbar spine of sheep, applicable in vivo, that minimizes the risk of post-surgical complications. This model was mechanically evaluated ex-vivo regarding its safety, and used to evaluate the injectability and radiopacity of two new bioceramic materials when compared to a commercial bioceramic bone substitute (Cerament™ SpineSupport). Microtomography techniques helped in the development of the model and results assessment. Under fluoroscopic guidance, a defect was created through a bilateral modified parapedicular access in the cranial hemivertebrae of 30 sheep lumbar vertebrae (L4, L5 and L6). The manually drilled defect had an average volume of 1209 ±226 mm3 and allowed the novel materials injection through a standardized injection cannula placed in one of the entrance points. Adequate defect filling was observed with all tested materials. No mechanical failure was observed under loads higher than the physiological. |
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Development of a sheep vertebroplasty model for bioceramic materials assessmentvertebroplastysheepbioceramicsDevelopment of a sheep vertebroplasty model for bioceramic materials assessment Sheep has been widely used as an animal orthopaedic model. Although several studies report anatomic and biomechanical similarities as well as distinctions of ovine lumbar vertebrae when compared to human’s, only a few studies describe its actual use as a vertebroplasty model. Due to distinct anatomic features, sheep lumbar vertebrae pose a challenge when developing a minimally invasive procedure for vertebroplasty material testing, under conditions meant to be the most similar to clinical procedure. The present work describes the development of an appropriate surgical percutaneous vertebroplasty model in the lumbar spine of sheep, applicable in vivo, that minimizes the risk of post-surgical complications. This model was mechanically evaluated ex-vivo regarding its safety, and used to evaluate the injectability and radiopacity of two new bioceramic materials when compared to a commercial bioceramic bone substitute (Cerament™ SpineSupport). Microtomography techniques helped in the development of the model and results assessment. Under fluoroscopic guidance, a defect was created through a bilateral modified parapedicular access in the cranial hemivertebrae of 30 sheep lumbar vertebrae (L4, L5 and L6). The manually drilled defect had an average volume of 1209 ±226 mm3 and allowed the novel materials injection through a standardized injection cannula placed in one of the entrance points. Adequate defect filling was observed with all tested materials. No mechanical failure was observed under loads higher than the physiological.European Materials Research Society Fall Meeting 20142015-01-22T15:07:28Z2015-01-222014-09-15T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjecthttp://hdl.handle.net/10174/12506http://hdl.handle.net/10174/12506porLucena, S, Oliveira, MT, Potes, J, Queiroga, MC, Rehman, S, Dalgarno, K, Ramos, A & Reis, J (2014): Development of a sheep vertebroplasty model for bioceramic materials assessment. European Materials Research Society Fall Meeting 2014, Warsow, Poland, 15-19 September 2014.simnaonaoslucena@uevora.ptmtalves@uevora.ptjacpotes@uevora.ptcrique@uevora.ptsarrawat.rehman@jri-ltd.co.ukkenny.dalgarno@newcastle.ac.uka.ramos@ua.ptjmfcr@uevora.pt206Lucena, SóniaOliveira, Maria TeresaPotes, JoséQueiroga, M. C.Rehman, SarrawatDalgarno, KennethRamos, AntónioReis, Joanainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-03T18:56:49Zoai:dspace.uevora.pt:10174/12506Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:05:54.388040Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Development of a sheep vertebroplasty model for bioceramic materials assessment |
title |
Development of a sheep vertebroplasty model for bioceramic materials assessment |
spellingShingle |
Development of a sheep vertebroplasty model for bioceramic materials assessment Lucena, Sónia vertebroplasty sheep bioceramics |
title_short |
Development of a sheep vertebroplasty model for bioceramic materials assessment |
title_full |
Development of a sheep vertebroplasty model for bioceramic materials assessment |
title_fullStr |
Development of a sheep vertebroplasty model for bioceramic materials assessment |
title_full_unstemmed |
Development of a sheep vertebroplasty model for bioceramic materials assessment |
title_sort |
Development of a sheep vertebroplasty model for bioceramic materials assessment |
author |
Lucena, Sónia |
author_facet |
Lucena, Sónia Oliveira, Maria Teresa Potes, José Queiroga, M. C. Rehman, Sarrawat Dalgarno, Kenneth Ramos, António Reis, Joana |
author_role |
author |
author2 |
Oliveira, Maria Teresa Potes, José Queiroga, M. C. Rehman, Sarrawat Dalgarno, Kenneth Ramos, António Reis, Joana |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Lucena, Sónia Oliveira, Maria Teresa Potes, José Queiroga, M. C. Rehman, Sarrawat Dalgarno, Kenneth Ramos, António Reis, Joana |
dc.subject.por.fl_str_mv |
vertebroplasty sheep bioceramics |
topic |
vertebroplasty sheep bioceramics |
description |
Development of a sheep vertebroplasty model for bioceramic materials assessment Sheep has been widely used as an animal orthopaedic model. Although several studies report anatomic and biomechanical similarities as well as distinctions of ovine lumbar vertebrae when compared to human’s, only a few studies describe its actual use as a vertebroplasty model. Due to distinct anatomic features, sheep lumbar vertebrae pose a challenge when developing a minimally invasive procedure for vertebroplasty material testing, under conditions meant to be the most similar to clinical procedure. The present work describes the development of an appropriate surgical percutaneous vertebroplasty model in the lumbar spine of sheep, applicable in vivo, that minimizes the risk of post-surgical complications. This model was mechanically evaluated ex-vivo regarding its safety, and used to evaluate the injectability and radiopacity of two new bioceramic materials when compared to a commercial bioceramic bone substitute (Cerament™ SpineSupport). Microtomography techniques helped in the development of the model and results assessment. Under fluoroscopic guidance, a defect was created through a bilateral modified parapedicular access in the cranial hemivertebrae of 30 sheep lumbar vertebrae (L4, L5 and L6). The manually drilled defect had an average volume of 1209 ±226 mm3 and allowed the novel materials injection through a standardized injection cannula placed in one of the entrance points. Adequate defect filling was observed with all tested materials. No mechanical failure was observed under loads higher than the physiological. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-09-15T00:00:00Z 2015-01-22T15:07:28Z 2015-01-22 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/conferenceObject |
format |
conferenceObject |
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publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10174/12506 http://hdl.handle.net/10174/12506 |
url |
http://hdl.handle.net/10174/12506 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Lucena, S, Oliveira, MT, Potes, J, Queiroga, MC, Rehman, S, Dalgarno, K, Ramos, A & Reis, J (2014): Development of a sheep vertebroplasty model for bioceramic materials assessment. European Materials Research Society Fall Meeting 2014, Warsow, Poland, 15-19 September 2014. sim nao nao slucena@uevora.pt mtalves@uevora.pt jacpotes@uevora.pt crique@uevora.pt sarrawat.rehman@jri-ltd.co.uk kenny.dalgarno@newcastle.ac.uk a.ramos@ua.pt jmfcr@uevora.pt 206 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
European Materials Research Society Fall Meeting 2014 |
publisher.none.fl_str_mv |
European Materials Research Society Fall Meeting 2014 |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799136544008699904 |